Results 71 to 80 of about 14,349 (139)

Guiding bar motif of thioredoxin reductase 1 modulates enzymatic activity and inhibitor binding by communicating with the co-factor FAD and regulating the flexible C-terminal redox motif

Redox Biology
Thioredoxin reductase (TXNRD) is a selenoprotein that plays a crucial role in cellular antioxidant defense. Previously, a distinctive guiding bar motif was identified in TXNRD1, which influences the transfer of electrons.
Wuyang Shi, Shibo Sun, Haowen Liu, Yao Meng, Kangshuai Ren, Guoying Wang, Minghui Liu, Jiaqi Wu, Yue Zhang, Huang Huang, Meiyun Shi, Weiping Xu, Qiang Ma, Bingbing Sun, Jianqiang Xu   +14 more
doaj   +1 more source

Functional diversity of YbbN/CnoX proteins: Insights from a comparative analysis of three thioredoxin-like oxidoreductases from Pseudomonas aeruginosa, Xylella fastidiosa and Escherichia coli

Redox Biology
YbbN/CnoX are proteins that display a Thioredoxin (Trx) domain linked to a tetratricopeptide domain. YbbN from Escherichia coli (EcYbbN) displays a co-chaperone (holdase) activity that is induced by HOCl.
Diogo de Abreu Meireles, César Henrique Yokomizo, Francisnei Pedrosa Silva, Thiago Motta Venâncio, Maximilia Frazão de Souza Degenhardt, Cristiano Luis Pinto de Oliveira, Luis Eduardo Soares Netto   +6 more
doaj   +1 more source

Crosstalk of thioredoxin system and programmed cell death: from pathophysiology to novel therapy. [PDF]

Redox Biol
Wu Y, Su Y, Pan F, Jin F, Huang H, Deng A, Lu Y, Lu Y, Li T, Du J, Tong X, Li Y.   +11 more
europepmc   +1 more source

1,2,3-Benzoxathiazine-2,2-Dioxides as Inhibitors of Thioredoxin Reductase. [PDF]

ChemMedChem
Ivanova J, Jackeviča L, Sizovs A, Bobrovs R, Žalubovskis R.   +4 more
europepmc   +1 more source

Response of Human Red Blood Cells to Acute and Chronic Oxidant Challenge as Observed Through the Glutathione and Glutathionyl-Hemoglobin Redox Pairs In Vitro and In Vivo. [PDF]

Molecules
Rubino FM.
europepmc   +1 more source

Inflammation and RONS Dysregulation by Redox Enzymes as Mechanistic Links in HIV-1-Cancer Comorbidity. [PDF]

Pathogens
Ang CG, Eyunni S, Chaiken IM.
europepmc   +1 more source

Unveiling the thioredoxin fold: a systematic review and bioinformatic analysis of protein disulfide isomerase and Dsb family proteins. [PDF]

Front Bioinform
Cuevas Ortiz D, Werner K, Frias Mayo MF, Cárdenas Arredondo PA, García Manzano GF, Revilla-Monsalve C, Retana H, Altamirano-Bustamante NF, Altamirano-Bustamante MM.   +8 more
europepmc   +1 more source

Disulfidptosis: The metabolic Achilles' heel of SLC7A11-high tumors and why oncology has missed it. [PDF]

Ann Med Surg (Lond)
Khawar MMH, Naeem I, Safi SU, Khawar M.
europepmc   +1 more source

Recent advances in exploring the composition and evolution of the prokaryotic selenoproteome. [PDF]

Appl Environ Microbiol
Zhang Y, Wang S, Li H, Chen X.
europepmc   +1 more source

Formation of the intradimer disulfide bond in human calprotectin maintains metal-withholding function and tunes proteolytic susceptibility. [PDF]

Chem Sci
Mollo A, Cool EY, Sakar B, Gupta K, Nolan EM.   +4 more
europepmc   +1 more source