Results 161 to 170 of about 17,263,040 (272)

From isotopologues to isotopomers: advances in mass spectrometry‐based positional 13C analysis in plants

New Phytologist, EarlyView.
Workflow of gas chromatography coupled to mass spectrometry (GC‐MS)‐based 13C‐labelling analysis of plant metabolites. Summary Carbon fluxes throughout metabolic networks can be investigated experimentally through 13C‐isotope labelling experiments (13C‐ILE) and 13C‐metabolic flux analysis (13C‐MFA).
Valéria F. Lima, Jônatas G.S.B. Oliveira, Luisa Wittemeier, Joachim Kopka, Danilo M. Daloso   +4 more
wiley   +1 more source

Epigenomic Cascades Across Organs in Metabolic Dysfunction–Associated Steatotic Liver Disease: New Therapeutic Horizons

Obesity Reviews, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is the most common chronic liver disorder worldwide, affecting approximately one‐third of the population and increasing the risk of severe hepatic and cardiovascular complications.
Shurui Yang, Zhongyu Huang, Sanchun Tan, Fengxia Liang, Li Chen   +4 more
wiley   +1 more source

Biomarkers Correlating With the Development of Oral Squamous Cell Carcinoma From Leukoplakia

Oral Diseases, EarlyView.
ABSTRACT Background We assessed protein biomarkers expressed in oral leukoplakia (OL) that are associated with the risk of transformation into oral squamous cell carcinoma (OSCC). Methods Tissue sections of OL transforming into OSCC (leuko‐ca), the corresponding OSCC and OL that did not progress to OSCC (leuko‐nonca) were analyzed with global relative ...
Daniel Giglio, Divya Ganesh, Bishwa Prakash Bhattarai, Tine Merete Søland, Jonas Sundberg, Annika Thorsell, Jenny Öhman, Dipak Sapkota, Bengt Hasséus   +8 more
wiley   +1 more source

Cytotoxic, chemosensitizing and radiosensitizing effects of curcumin based on thioredoxin system inhibition in breast cancer cells: 2D vs. 3D cell culture system. [PDF]

Exp Ther Med, 2021
El Feky SE, Ghany Megahed MA, Abd El Moneim NA, Zaher ER, Khamis SA, Ali LMA.   +5 more
europepmc   +1 more source

Single‐Nucleus Transcriptome Analysis Provides New Insights Into B Chromosome Elimination in Sorghum

Plant Biotechnology Journal, EarlyView.
ABSTRACT B chromosomes are supernumerary entities found in many plant species, with some exhibiting tissue‐specific elimination. In Sorghum purpureosericeum, extensive B chromosome elimination occurs during embryogenesis affecting most of the embryonic organs, leaving the B chromosome maintained mainly in limited regions of meristems.
T. Bojdová, P. Abaffy, L. Valihrach, M. Karafiátová, J. Bartoš   +4 more
wiley   +1 more source

Thioredoxin system modulates metabolic and stomatal responses to elevated CO₂ in Arabidopsis. [PDF]

New Phytol
da Fonseca-Pereira P, Mélo Neto DF, Monteiro-Batista RC, Coelho DG, Lana-Costa J, de Souza LP, Krahnert I, Daloso DM, Gago J, Fernie AR, Araújo WL, Nunes-Nesi A.   +11 more
europepmc   +1 more source

Libertellenone H, a Natural Pimarane Diterpenoid, Inhibits Thioredoxin System and Induces ROS-Mediated Apoptosis in Human Pancreatic Cancer Cells. [PDF]

Molecules, 2021
Zhang W, Zhu Y, Yu H, Liu X, Jiao B, Lu X.   +5 more
europepmc   +1 more source

Complex Redundancy between the Mammalian Thioredoxin and Glutathione Systems in Cell Proliferation and Tumorigenesis Thesis [PDF]

, 2009
Mandal, Pankaj Kumar
core   +1 more source

Redox‐regulated signalling of adaptations to contractile activity in skeletal muscle: Implications for age‐related muscle weakness

Experimental Physiology, EarlyView.
Abstract Skeletal muscle adaptation to contractile activity is modulated by redox signalling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). Early research framed ROS as deleterious byproducts of exercise, but subsequent studies have established their roles as signalling molecules involved in mitochondrial biogenesis,
Malcolm J. Jackson
wiley   +1 more source

Thioredoxin system dysregulation and calpain activation drive myocardial disulfidptosis via pathological disulfide bonds remodeling. [PDF]

Cell Death Discov
Tang A, Chen B, Zhang W, Gong Z, Jin M, Xu X, Shi Y, Chen W.   +7 more
europepmc   +1 more source