Results 21 to 30 of about 7,819 (191)

Synergistic Photothermal-Chemotherapy of Hepatocellular Carcinoma and Cancer Stem Cells via in situ pH-Responsive Hydrogels [PDF]

International Journal of Nanomedicine
Yunchao Wu,1,* Xin Xu,1,* Zhen Zhu,1 Fengyi Du,2 Guojun Zheng1 1Central Laboratory, The Affiliated Changzhou Hospital of Xuzhou Medical University, Changzhou Third People’s Hospital, Changzhou, Jiangsu, 213000, People’s Republic of China;
Wu Y, Xu X, Zhu Z, Du F, Zheng G
doaj   +2 more sources

Type IV Pilus-Mediated Inhibition of Acinetobacter baumannii Biofilm Formation by Phenothiazine Compounds

Microbiology Spectrum, 2023
Infections by pathogenic Acinetobacter species represent a significant burden on the health care system, despite their relative rarity, due to the difficulty of treating infections through oral antibiotics.
Nam Vo, Benjamin S. Sidner, Yafan Yu, Kurt H. Piepenbrink   +3 more
doaj   +1 more source

Thioridazine for dementia.

, 2023
BACKGROUND: Neuroleptic drugs are controversial treatments in dementia, with evidence accumulating that they may hasten clinical decline. Despite these concerns, they are commonly prescribed for elderly and demented patients.
C A Kelly (13591354), Richard Harvey (13090974), V Kirchner (13591429)   +2 more
core   +1 more source

A Carbon Nanocomposite Ionic Liquid Electrode Based on Montmorillonite Nanoclay for Sensitive Voltammetric Determination of Thioridazine

International Journal of Electrochemical Science, 2014
A carbon nanocomposite electrode has been designed by incorporation of montmorillonite nanoclay into the carbon ionic liquid electrode for the electrochemical determination of (10-[2-(1-methyl-2- piperidyl) ethyl]-2-methylthiophenothiazine) (thioridazine)
P.Aberoomand Azar, F. Farjami, M.Saber Tehrani, E. Eslami   +3 more
doaj   +1 more source

Unraveling antibiotic resistance mechanisms in Mycobacterium abscessus: the potential role of efflux pumps

Journal of Global Antimicrobial Resistance, 2022
: Objectives: Mycobacterium abscessus is an opportunistic respiratory pathogen in patients with underlying lung disease. It is infamously known for its low treatment success rates because of its resistance to multiple classes of antibiotics.
Saskia E. Mudde, Jodie A. Schildkraut, Nicole C. Ammerman, Corné P. de Vogel, Jurriaan E.M. de Steenwinkel, Jakko van Ingen, Hannelore I. Bax   +6 more
doaj   +1 more source

A Novel Derivative of Thioridazine Shows Low Toxicity and Efficient Activity against Gram-Positive Pathogens

Antibiotics, 2020
Thioridazine hydrochloride (HCl) has been suggested as a promising antimicrobial helper compound for the treatment of infections with antimicrobial-resistant bacteria.
Nadia S. Jørgensen, Lasse Saaby, Anne M. Andersson, Sofie Kromann, Ehsan Sheikhsamani, Anders Permin, Troels Ronco, Søren W. Svenningsen, Jørn B. Christensen, Rikke H. Olsen   +9 more
doaj   +1 more source

Antibacterial properties of thioridazine

Фармацевтичний журнал, 2019
The emergence and spread of antibiotic-resistant strains of microorganisms reduces the effectiveness of antibiotic therapy and requires finding solutions to problems, one of which is the study of antimicrobial properties in drugs of various ...
N. Hrynchuk, N. Vrynchanu
doaj   +1 more source

Descemet's stripping-automated endothelial keratoplasty for symptomatic thioridazine deposits in the cornea

Taiwan Journal of Ophthalmology, 2017
The aim of this study was to use Descemet's Stripping-automated Endothelial Keratoplasty (DSAEK) as a novel treatment to remove thioridazine corneal deposits. A 53-year-old female presented with a 3-month history of visual loss and glare.
Masoumeh Mohebbi, Hassan Hashemi, Alireza Mahmoudi, Pasha Anvari   +3 more
doaj   +1 more source

Tentative susceptibility testing breakpoint for the neuroleptic drug thioridazine, a treatment option for multi- and extensively drug resistant tuberculosis

International Journal of Mycobacteriology, 2012
Introduction: New drugs against multi-(MDR) and extensively drug (XDR) resistant tuberculosis are urgently needed. While new candidate drugs are being developed, reinvestigation of already approved drugs available for other indications could be of value.
Kristian Angeby, Pontus Juréen, Erja Chryssanthou, Thomas Schön   +3 more
doaj   +1 more source

Factors affecting drug concentrations and QT interval during thioridazine therapy

The objective of this study was to investigate factors affecting steady-state plasma concentrations of thioridazine. A cross-sectional study of patients receiving chronic thioridazine was employed.
Thomas SHL, Daly AK, Thanacoody RHK, Reilly JG, Ferrier IN   +4 more
core   +5 more sources