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Structure of salicylaldehyde thiosemicarbazone

Acta Crystallographica Section C Crystal Structure Communications, 1988
C8H9N3OS, monoclinic, C2/c, a = 14.206 (3), b = 14.244 (4), c = 10.457 (4) A, beta = 116.18(2) degrees, V = 1898.9 (8) A3, Z = 8, Dm = 1.387, D chi = 1.366 g cm-3, lambda(Mo K alpha) = 0.71069 A, mu = 2.90 cm-1, F(000) = 816.0, T = 298 K, final R = 0.0429 for 1322 observed reflections. The S and hydrazinic N atoms lie trans.
D, Chattopadhyay   +4 more
openaire   +2 more sources

Hydroxyphenyl thiosemicarbazones as inhibitors of mushroom tyrosinase and antibrowning agents.

Food Chemistry, 2020
Tyrosinase is a metalloenzyme involved in o-hydroxylation of monophenols and oxidation of o-diphenols to o-quinones, with formation of brown or black pigments (melanines).
M. Carcelli   +8 more
semanticscholar   +1 more source

Biodistribution of 59Fe-thiosemicarbazones

International Journal of Nuclear Medicine and Biology, 1982
The 59Fe-iron(II) chelates of 2-formylpyridine thiosemicarbazone (I), 5-dimethylamino-2-formylpyridine thiosemicarbazone (II), and 5-hydroxy-2-formylpyridine thiosemicarbazone (III) were prepared and their biodistribution determined in normal rats. Early accumulation of these complexes occurred in the liver, muscle and pelt with lesser amounts in the ...
R N, Hanson, M A, Davis
openaire   +2 more sources

Semicarbazones and thiosemicarbazones. VII. Structure of 2-hydroxyacetophenone thiosemicarbazone

Acta Crystallographica Section C Crystal Structure Communications, 1988
Cristallisation dans P 21n avec affinement jusqu'a 0,042. L'atome S est situe en trans par rapport a l'atome N du groupe hydrazine.
M. Soriano-García   +2 more
openaire   +1 more source

Synthesis, cytotoxicity and antimalarial activities of thiosemicarbazones and their nickel (II) complexes

, 2020
A series of Schiff base metal complexes with the formulations [Ni(L1)2] (4), [Ni(L2)2] (5) and [Ni(L3)2] (6), (where 1 or L1 = fluorene-2-carboxaldehyde thiosemicarbazone, 2 or L2 = fluorene-2-carboxaldehyde-4-methyl-thiosemicarbazone and 3 or L3 ...
Savina Savir   +7 more
semanticscholar   +1 more source

Synthesis and comparison of antileishmanial and cytotoxic activities of S-(−)-limonene benzaldehyde thiosemicarbazones with their R-(+)-analogues

Journal of Molecular Structure, 2019
In this study, we explore a series of novel potential antiprotozoal S-(−)-limonene-based benzaldehyde thiosemicarbazones were synthesised and their activity effective against the extracellular promastigote form of Leishmania amazonensis examined ...
Diogo Noin De Oliveira   +2 more
exaly   +2 more sources

Anticancer activity of the thiosemicarbazones that are based on di-2-pyridine ketone and quinoline moiety.

European journal of medicinal chemistry, 2019
Thiosemicarbazones (TSC) are a subclass of iron-chelating agents that are believed to have an anticancer activity. The high potential for the application of this compound class can be illustrated by a fact that three TSC have entered clinical trials. The
A. Mrozek-Wilczkiewicz   +4 more
semanticscholar   +1 more source

Synthesis and characterization of new thiosemicarbazones, as potent urease inhibitors: In vitro and in silico studies.

Bioorganic chemistry (Print), 2019
A new series of N-substituted thiosemicarbazones (3a-u) bearing 2-naphthyl and dihydrobenzofuranyl scaffolds were synthesized in good to excellent yields (78-95%). The synthesized compounds were characterized by advanced spectroscopic techniques, such as
Muhammad Islam   +11 more
semanticscholar   +1 more source

Semicarbazones and thiosemicarbazones, XIII: Study of the hydrolysis of coordinated thiosemicarbazones

Monatshefte f�r Chemie Chemical Monthly, 1991
The hydrolysis of coordinated thiosemicarbazones was studied. It was found that the nickel(II) ion promotes the reaction. Steric and electronic influences were found. The hydrolysis ofATSC in the trigonal bipyramid compounds [M(ATSC)2Cl]Cl [M=Fe(II), Co(II), Ni(II)], is higher with the Ni(II) complex, the compound with the shorterM-N distance.
Armando Cabrera   +3 more
openaire   +1 more source

Synthesis, antibacterial activity and docking studies of substituted quinolone thiosemicarbazones

Phosphorus Sulfur and Silicon and the Related Elements, 2019
Fifteen 2-quinolone thiosemicarbazone derivatives of which eleven were new, were synthesized at room temperature. The key intermediate was the quinolone carbaldehyde, from which thiosemicarbazones were formed by the reaction of thiosemicarbazides with ...
Hogantharanni Govender   +3 more
semanticscholar   +1 more source

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