Results 31 to 40 of about 3,023 (198)
Supersulfide biology and translational medicine for disease control
British Journal of Pharmacology, EarlyView., 2023 Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu +5 more
wiley +1 more source
Sulfane sulfur deficiency in malignant cells, increasing the inhibiting action of acetone cyanohydrin in tumor growth [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: To demonstrate the irreversible poisoning action of the acetone cyanohydrin (AC) in malignant cells. METHODS: Thirty male Swiss mice were inoculated with 1x10³ Ehrlich tumor (ET) cells. The mice were divided into three groups (n=10): CG (saline);
Rondon Tosta Ramalho +4 more
doaj +1 more source
Hypertension and Aging Affect Liver Sulfur Metabolism in Rats
Cells, 2021 Hypertension and age are key risk factors for cardiovascular morbidity and mortality. Hydrogen sulfide (H2S), a gaseous transmitter, contributes significantly to regulating arterial blood pressure and aging processes.
Dominika Szlęzak +4 more
doaj +1 more source
Proteomic analysis and interactions network in leaves of mycorrhizal and nonmycorrhizal sorghum plants under water deficit [PDF]
PeerJ, 2020 For understanding the water deficit stress mechanism in sorghum, we conducted a physiological and proteomic analysis in the leaves of Sorghum bicolor L.
Víctor Olalde-Portugal +5 more
doaj +2 more sources
Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]
, 2020 Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core +1 more source
The Pol III transcriptome: Basic features, recurrent patterns, and emerging roles in cancer
WIREs RNA, Volume 14, Issue 5, September/October 2023., 2023 The Pol III transcriptome: basic features, recurrent patterns, and emerging roles in cancer. Abstract The RNA polymerase III (Pol III) transcriptome is universally comprised of short, highly structured noncoding RNA (ncRNA). Through RNA–protein interactions, the Pol III transcriptome actuates functional activities ranging from nuclear gene regulation ...
Sihang Zhou, Kevin Van Bortle
wiley +1 more source
Bioactivity and health effects of garlic essential oil: A review
Food Science &Nutrition, Volume 11, Issue 6, Page 2450-2470, June 2023., 2023 This paper reviews the research progress on the composition and bioactivities of garlic essential oil mixtures and the bioactivity of some typical monomeric sulfides in garlic essential oil. The active mechanisms of representative sulfides in garlic essential oil were analyzed, and the applications of garlic essential oil in functional food, food ...
Lei Huang +6 more
wiley +1 more source
Journal of Oncology, Volume 2023, Issue 1, 2023., 2023 Hepatocellular carcinoma (HCC) is a disease with high morbidity, high mortality, and low cure rate. Hyaluronic acid (HA) is widely adopted in tissue engineering and drug delivery. 5‐(4‐Hydroxyphenyl)‐3H‐1, 2‐dithiol‐3‐thione (ADT‐OH) is one of commonly used H2S donors.
Shao-Feng Duan +12 more
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 88, Issue 11, Page 4812-4827, November 2022., 2022 Aims The aim of this study was to determine if any suspected adverse drug reactions (ADRs) observed with the use of angiotensin II receptor blockers (ARBs) could be linked to either (a) their unique respective physicochemical and pharmacological profiles and (b) the recently disclosed suspected carcinogenic manufacturing contaminants found in certain ...
Hamisha Salim, Alan M. Jones
wiley +1 more source