Sulfurtransferases and Cystathionine Beta-Synthase Expression in Different Human Leukemia Cell Lines
The studies concerned the expression of sulfurtransferases and cystathionine beta-synthase in six human leukemia cell lines: B cell acute lymphoblastic leukemia-B-ALL (REH cells), T cell acute lymphoblastic leukemia-T-ALL (DND-41 and MOLT-4 cells), acute
Halina Jurkowska +3 more
doaj +1 more source
Discovery of a small molecule allosteric activator of human thiosulfate sulfurtransferase [PDF]
Recent studies showed that thiosulfate sulfurtransferase (TST) is one of the few peripherally expressed genes that has been identified as a genetic risk factor for metabolic health, with clear evidence of a negative correlation with the development of ...
Al Dahmani-Al Zakwani, Zayana +2 more
core +1 more source
Hydrogen sulfide (H2S) is a toxic gas that has important regulatory functions. In the colon, H2S can be produced and detoxified endogenously. Both too little and too much H2S exposure are associated with inflammatory bowel disease (IBD), a chronic ...
Nathalie Stummer +10 more
doaj +1 more source
Sulfane sulfur deficiency in malignant cells, increasing the inhibiting action of acetone cyanohydrin in tumor growth [PDF]
PURPOSE: To demonstrate the irreversible poisoning action of the acetone cyanohydrin (AC) in malignant cells. METHODS: Thirty male Swiss mice were inoculated with 1x10³ Ehrlich tumor (ET) cells. The mice were divided into three groups (n=10): CG (saline);
Rondon Tosta Ramalho +4 more
doaj +1 more source
Hypertension and Aging Affect Liver Sulfur Metabolism in Rats
Hypertension and age are key risk factors for cardiovascular morbidity and mortality. Hydrogen sulfide (H2S), a gaseous transmitter, contributes significantly to regulating arterial blood pressure and aging processes.
Dominika Szlęzak +4 more
doaj +1 more source
Thiosulfate-Cyanide Sulfurtransferase a Mitochondrial Essential Enzyme: From Cell Metabolism to the Biotechnological Applications [PDF]
Thiosulfate: cyanide sulfurtransferase (TST), also named rhodanese, is an enzyme widely distributed in both prokaryotes and eukaryotes, where it plays a relevant role in mitochondrial function. TST enzyme is involved in several biochemical processes such
Arciero, Ilaria +8 more
core +1 more source
Proteomic analysis and interactions network in leaves of mycorrhizal and nonmycorrhizal sorghum plants under water deficit [PDF]
For understanding the water deficit stress mechanism in sorghum, we conducted a physiological and proteomic analysis in the leaves of Sorghum bicolor L.
Víctor Olalde-Portugal +5 more
doaj +2 more sources
Histopathological evaluation of tumor necrosis and volume after cyanogenic chemotherapy [PDF]
PURPOSE:To determine the percentage of tumoral necrosis and volume after cyanogenic chemotherapy.METHODS:Histopathological findings of 20 Swiss mice inoculated subcutaneously in the left abdominal wall with 0.05 ml of cell suspension containing 2.5 x 105
Rondon Tosta Ramalho +3 more
doaj +1 more source
Recently, a CRISPR-Cas9 genome-editing system was developed with introduced sequential ‘driver’ mutations in the WNT, MAPK, TGF-β, TP53 and PI3K pathways into organoids derived from normal human intestinal epithelial cells.
Kelly Ascenção +5 more
doaj +1 more source
Transcription factor YcjW controls the emergency H2S production in E. coli
Hydrogen sulfide (H2S) production in Escherichia coli is controlled by the sulfurtransferase 3MST. Here, the authors describe an alternative mechanism for H2S biosynthesis via activation of the thiosulfate sulfurtransferase PspE, a process mediated by ...
Lyly Luhachack +3 more
doaj +1 more source

