Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284. [PDF]
FEBS LettTuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Di Napoli G +10 more
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Sulfurtransferases and Cystathionine Beta-Synthase Expression in Different Human Leukemia Cell Lines
Biomolecules, 2022 The studies concerned the expression of sulfurtransferases and cystathionine beta-synthase in six human leukemia cell lines: B cell acute lymphoblastic leukemia-B-ALL (REH cells), T cell acute lymphoblastic leukemia-T-ALL (DND-41 and MOLT-4 cells), acute
Halina Jurkowska +3 more
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Antioxidants, 2022 Hydrogen sulfide (H2S) is a toxic gas that has important regulatory functions. In the colon, H2S can be produced and detoxified endogenously. Both too little and too much H2S exposure are associated with inflammatory bowel disease (IBD), a chronic ...
Nathalie Stummer +10 more
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Sulfane sulfur deficiency in malignant cells, increasing the inhibiting action of acetone cyanohydrin in tumor growth [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: To demonstrate the irreversible poisoning action of the acetone cyanohydrin (AC) in malignant cells. METHODS: Thirty male Swiss mice were inoculated with 1x10³ Ehrlich tumor (ET) cells. The mice were divided into three groups (n=10): CG (saline);
Rondon Tosta Ramalho +4 more
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Hypertension and Aging Affect Liver Sulfur Metabolism in Rats
Cells, 2021 Hypertension and age are key risk factors for cardiovascular morbidity and mortality. Hydrogen sulfide (H2S), a gaseous transmitter, contributes significantly to regulating arterial blood pressure and aging processes.
Dominika Szlęzak +4 more
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Proteomic analysis and interactions network in leaves of mycorrhizal and nonmycorrhizal sorghum plants under water deficit [PDF]
PeerJ, 2020 For understanding the water deficit stress mechanism in sorghum, we conducted a physiological and proteomic analysis in the leaves of Sorghum bicolor L.
Víctor Olalde-Portugal +5 more
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Antioxidants, 2019 The antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase (MST, EC 2.8.1.2) is localized in the cytosol and mitochondria, while the evolutionarily-related enzyme, rhodanese (thiosulfate sulfurtransferase, TST, EC 2.8.1.1) is localized in the ...
Noriyuki Nagahara +3 more
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Structural and biochemical characterization of an encapsulin-associated rhodanese from Acinetobacter baumannii. [PDF]
Protein SciAbstract Rhodanese‐like domains (RLDs) represent a widespread protein family canonically involved in sulfur transfer reactions between diverse donor and acceptor molecules. RLDs mediate these transsulfuration reactions via a transient persulfide intermediate, created by modifying a conserved cysteine residue in their active sites.
Benisch R, Giessen TW.
europepmc +2 more sources
Histopathological evaluation of tumor necrosis and volume after cyanogenic chemotherapy [PDF]
Acta Cirúrgica Brasileira, 2014 PURPOSE:To determine the percentage of tumoral necrosis and volume after cyanogenic chemotherapy.METHODS:Histopathological findings of 20 Swiss mice inoculated subcutaneously in the left abdominal wall with 0.05 ml of cell suspension containing 2.5 x 105
Rondon Tosta Ramalho +3 more
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Transcription factor YcjW controls the emergency H2S production in E. coli
Nature Communications, 2019 Hydrogen sulfide (H2S) production in Escherichia coli is controlled by the sulfurtransferase 3MST. Here, the authors describe an alternative mechanism for H2S biosynthesis via activation of the thiosulfate sulfurtransferase PspE, a process mediated by ...
Lyly Luhachack +3 more
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