Transcription factor YcjW controls the emergency H2S production in E. coli
Nature Communications, 2019 Hydrogen sulfide (H2S) production in Escherichia coli is controlled by the sulfurtransferase 3MST. Here, the authors describe an alternative mechanism for H2S biosynthesis via activation of the thiosulfate sulfurtransferase PspE, a process mediated by ...
Lyly Luhachack +3 more
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CoQ deficiency causes disruption of mitochondrial sulfide oxidation, a new pathomechanism associated with this syndrome [PDF]
, 2017 Coenzyme Q (CoQ) is a key component of the mitochondrial respiratory chain, but it also has several other functions in the cellular metabolism. One of them is to function as an electron carrier in the reaction catalyzed by sulfide:quinone oxidoreductase (
Barriocanal-Casado, Eliana +5 more
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H2S, Polysulfides, and Enzymes: Physiological and Pathological Aspects
Biomolecules, 2020 We have been studying the general aspects of the functions of H2S and polysulfides, and the enzymes involved in their biosynthesis, for more than 20 years.
Noriyuki Nagahara, Maria Wróbel
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Conformational studies on Arabidopsis sulfurtransferase AtStr1 with spectroscopic methods [PDF]
, 2007 Sulfurtransferases/rhodaneses (Str) are enzymes widely distributed in archaea, prokaryota and eukaryota, and catalyze the transfer of sulfur from a donor molecule to a thiophilic acceptor substrate.
Bartels, Andrea +3 more
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Antioxidants, 2022 Recently, a CRISPR-Cas9 genome-editing system was developed with introduced sequential ‘driver’ mutations in the WNT, MAPK, TGF-β, TP53 and PI3K pathways into organoids derived from normal human intestinal epithelial cells.
Kelly Ascenção +5 more
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The Quantitative Significance of the Transsulfuration Enzymes for H2S Production in Murine Tissues [PDF]
, 2011 The enzymes of the transsulfuration pathway, cystathionine --synthase (CBS) and cystathionine --lyase (CSE), are important for the endogenous production of hydrogen sulfide (H2S), a gaseous signaling molecule. The relative contributions of CBS and CSE to
Kery V +6 more
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Frontiers in Oncology, 2022 Epigenetic alterations play a pivotal role in cancer treatment outcomes. Using the methylation array data and The Cancer Genome Atlas (TCGA) dataset, we observed the hypomethylation and upregulation of thiosulfate sulfurtransferase–like domain containing
Muhamad Ansar +14 more
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Past, present and future of cyanide antagonism research: From the early remedies to the current therapies. [PDF]
, 2015 This paper reviews milestones in antidotal therapies for cyanide (CN) spanning early remedies, current antidotal systems and research towards next generation therapies. CN has been a part of plant defense mechanisms for millions of years.
Budai, Marianna +3 more
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Allyl sulfur compounds and cellular detoxification system: effects and perspectives in cancer therapy [PDF]
, 2011 Natural organosulfur compounds (OSCs) have been shown to have chemopreventive effects and to suppress the proliferation of tumor cells in vitro through the induction of apoptosis.
Melino, S, Paci, M, Sabelli, R
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In Vivo Anti-inflammatory Activity of Lipoic Acid Derivatives in Mice [PDF]
, 2013 Background: In mammals lipoic acid (LA) and its reduced form dihydrolipoic acid (DHLA) function as cofactors for multienzymatic complexes catalyzing the decarboxylation of α-ketoacids.
Anna Bilska-Wilkosz +10 more
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