Results 221 to 230 of about 884,746 (312)

Multidimensional third-generation sequencing of modified DNA bases allows interrogation of complex biological systems. [PDF]

Nat Commun
David SS, Pacheco BA, Kishimoto K, Vantine S, Hu K, Liu H, Davis DL, Tran H, Sallis BF, Ali L, Haynes CM, McCormick BA, Zhu LJ, Flavahan WA.   +13 more
europepmc   +1 more source

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source

Identification of a novel complex variant in a patient involving the α-globin gene cluster by third-generation sequencing. [PDF]

Ann Hematol
Liu H, Du Y, Yang Y, Cui D, Chen L, Zhou C, Wang J.   +6 more
europepmc   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Development and application of sex-specific indel markers for Hippophae salicifolia based on third-generation sequencing. [PDF]

BMC Plant Biol
Zeng Z, Zhang S, Tan X, Tso N, Shang Z, Zhang J, Li W, Wang J, Zhang W, Qiong.   +9 more
europepmc   +1 more source

Molecular typing by third generation, long-read sequencing

Der Anstieg von antibiotikaresistenten Bakterien, im Speziellen das Auftreten von so genannten multiresistenten „Superbugs“, erschwert die Behandlung von Infektionskrankheiten zunehmend. Der derzeitige Goldstandard für die Antibiotika-Resistenztestung sind antimikrobielle Empfindlichkeitstests (antimicrobial susceptibility test, AST), bei dem manuell ...
openaire   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Application of third-generation sequencing technology in the genetic testing of thalassemia. [PDF]

Mol Cytogenet
Li W, Ye Y.
europepmc   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Whole genome study and construction of SHERLOCK detection method for endemic strains of <i>Burkholderia pseudomallei</i> in Hainan based on third-generation sequencing. [PDF]

Microbiol Spectr
Hu J, Xu S, Zeng Z, Gong W, Xu W, Ma Z, Fu S, Li L, Xiao B, Chen X.   +9 more
europepmc   +1 more source