Results 11 to 20 of about 1,212 (144)

Experimental and evolutionary evidence for horizontal transfer of an envelope fusion protein gene between thogotoviruses and baculoviruses [PDF]

Journal of Virology
Baculoviruses are insect-specific viruses with large, double-stranded DNA genomes classified into four genera. Alphabaculoviruses, which infect lepidoptera, are further divided into group I (G1-α) and group II (G2-α). The GP64 protein, essential for cell
Bruno Milhomem Pilati Rodrigues, Luis Janssen, Leonardo Assis da Silva, Suzane Suliane Vitorino Gomes Acacio, Mariana Tigano Magalhães, Bergmann Morais Ribeiro   +5 more
doaj   +2 more sources

DHORI VIRUS (ORTHOMYXOVIRIDAE: THOGOTOVIRUS) INFECTION IN MICE: A MODEL OF THE PATHOGENESIS OF SEVERE ORTHOMYXOVIRUS INFECTION [PDF]

The American Journal of Tropical Medicine and Hygiene, 2007
After intranasal, subcutaneous, or intraperitoneal infection with Dhori virus (DHOV), adult mice developed a fulminant and uniformly fatal illness with many of the clinical and pathologic findings seen in mice infected with H5N1 highly pathogenic avian influenza A virus.
ROSA I. MATEO, Shu‐Yuan Xiao, Hao Lei, Amélia P. A. Travassos da Rosa, Robert B. Tesh   +4 more
openalex   +3 more sources

Involvement of a tick-borne orthomyxovirus matrix protein in vRNP nuclear export [PDF]

Journal of Virology
Thogotoviruses are arthropod-borne viruses belonging to the genus Thogotovirus within the family Orthomyxoviridae. Like other orthomyxoviruses, such as the influenza A viruses (IAV), thogotoviruses replicate in the nucleus.
Vaille A. Swenson, Jack Hemsath, Iris Yousaf, Carla Weisend, Michael A. Barry, Hideki Ebihara, Satoko Yamaoka   +6 more
doaj   +2 more sources

Molecular, serological and in vitro culture-based characterization of Bourbon virus, a newly described human pathogen of the genus Thogotovirus [PDF]

Journal of Clinical Virology, 2015
In June of 2014, a previously healthy man from Kansas with a recent history of tick exposure died from complications related to an illness marked by fever, thrombocytopenia and leukopenia. An isolate was derived from the blood of this patient during the course of diagnostic testing.
Amy J. Lambert, Jason O. Velez, Aaron C. Brault, Amanda E. Calvert, Lesley Bell‐Sakyi, Angela M. Bosco‐Lauth, J. Erin Staples, Olga I. Kosoy   +7 more
openalex   +3 more sources

ANP32 proteins from ticks and vertebrates are key host factors for replication of Bourbon virus across species [PDF]

Journal of Virology
Bourbon virus (BRBV) is a tick-borne virus in the genus Thogotovirus in the Orthomyxoviridae family. BRBV was initially identified as the presumptive causative agent of a fatal human infection in 2014 and has since been identified in ticks in the Midwest,
Zhenyu Zhang, Ishmael D. Aziati, Thomas Nipper, Adrianus C. M. Boon, Andrew Mehle   +4 more
doaj   +2 more sources

Surveillance for Tick-Borne Viruses Near the Location of a Fatal Human Case of Bourbon Virus (Family Orthomyxoviridae: Genus Thogotovirus) in Eastern Kansas, 2015 [PDF]

Journal of Medical Entomology, 2018
Bourbon virus (Family Orthomyxoviridae: Genus Thogotovirus) was first isolated from a human case-patient residing in Bourbon County, Kansas, who subsequently died. Before becoming ill in late spring of 2014, the patient reported several tick bites. In response, we initiated tick surveillance in Bourbon County and adjacent southern Linn County during ...
Harry M. Savage, Marvin S. Godsey, Nicholas A. Panella, Kristen L. Burkhalter, Justin Manford, Ingrid Trevino-Garrison, Anne Straily, Savannah Wilson, Jaden Bowen, Ram K. Raghavan   +9 more
openalex   +3 more sources

Diverse virome and potential pathogens in five tick species from metropolis surroundings of Beijing and Tianjin, China [PDF]

npj Biofilms and Microbiomes
Rapid urbanization and dense populations in metropolitan areas increase the risk of tick-borne disease transmission. We profiled 139 RNA libraries of 1697 adult ticks belonging to Haemaphysalis longicornis, Haemaphysalis concinna, Dermacentor silvarum ...
Wan‑Ying Gao, Xian Xia, Tian‑Hong Wang, Ya‑Ting Liu, Juan Wang, Yu‑Yu Li, Luo-Yuan Xia, Na Jia, Jia-Fu Jiang, Yi Sun, Xiao-Ming Cui, Run‑Ze Ye, Lin Zhao, Wu‑Chun Cao   +13 more
doaj   +2 more sources

Sinu virus, a novel and divergent orthomyxovirus related to members of the genus Thogotovirus isolated from mosquitoes in Colombia

Virology, 2016
The genome and structural organization of a novel insect-specific orthomyxovirus, designated Sinu virus, is described. Sinu virus (SINUV) was isolated in cultures of C6/36 cells from a pool of mosquitoes collected in northwestern Colombia. The virus has six negative-sense ssRNA segments. Genetic analysis of each segment demonstrated the presence of six
María Angélica Contreras-Gutiérrez, Márcio Roberto Teixeira Nunes, Hilda Guzmán, Sandra Uribe, Juan Carlos Gallego-Gómez, Juan David Suaza Vasco, Jedson Ferreira Cardoso, Vsevolod L. Popov, Steven G. Widen, Thomas G. Wood, Nikos Vasilakis, Robert B. Tesh   +11 more
openalex   +5 more sources

Development of a Double-Antigen Sandwich ELISA for Oz Virus and a Seroepidemiological Survey in Wild Boars in Miyazaki, Japan [PDF]

Pathogens
Oz virus, an emerging tick-borne thogotovirus, has been reported to cause fatal human infection in Japan. However, its ecology and geographic distribution remain largely unknown.
Hirohisa Mekata, Mari Yamamoto, Aya Matsuu, Ken Maeda, Haruhiko Isawa, Kentaro Yoshii, Kazumi Umeki, Tamaki Okabayashi   +7 more
doaj   +2 more sources

Molecular Epidemiology and Seroepidemiology of Oz Virus Infection in Ticks and Wild Boars in Ibaraki Prefecture, Japan [PDF]

Microorganisms
Oz virus (OZV), an emerging negative-sense single-stranded RNA virus classified under the family Orthomyxoviridae and genus Thogotovirus, was first isolated from Amblyomma testudinarium ticks in Ehime Prefecture, Japan, in 2013.
Shuichi Osawa, Hirokazu Kimura, Sakurako Abe, Noriko Nagata, Eri Ueno, Hideki Ebihara, Ryusuke Kimura, Tetsuya Furuya   +7 more
doaj   +2 more sources