Three-Component Ring-Expansion Reaction of Indoles Leading to Synthesis of Pyrrolo[2,3‑c]quinolines [PDF]
, 2023 Herein, we have developed an atom- and step-economic three-component cascade reaction that enables a modular platform for the synthesis of pyrrolo[2,3-c]quinoline compounds through ring-expansion/cyclization by way of novel N1–C2 cleavage of indoles. The
Xinping Liu +13 more
core +1 more source
Copper(I) Halide Catalyzed Three-Component Coupling Reaction of Aldehyde, Pyrrolidine and Stannyl- and Silylacetylene [PDF]
, 2013 An efficient three-component coupling reaction of aldehyde, pyrrolidine and tributylstannylacetylene or triphenylsilylacety-lene to generate propargylamines has been developed by using copper(I) halides as promoters ...
Lee, Adam Shih-Yuan +1 more
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Pd-Catalyzed Dearomative Three-Component Reaction of Bromoarenes with Diazo Compounds and Allylborates [PDF]
, 2019 Acatalytic dearomative three-component reaction of bromoarenes with TMS-diazomethane and allyl borate was developed. The key of this assembling reaction is the use of a diazo compound to generate a Pd-π-benzyl intermediate through a Pd-carbenoid species.
Junichiro, Yamaguchi +3 more
core +1 more source
Three-Component Approach to Densely Functionalized Trifluoromethyl Allenols by Asymmetric Organocatalysis [PDF]
, 2023 We have developed a new three-component catalytic coupling reaction of alkynyl boronates, diazomethanes, and aliphatic/aromatic ketones in the presence of BINOL derivatives.
Marie Deliaval (8621637) +7 more
core +1 more source
5-(4-Fluorophenyl)-3-(naphthalen-1-yl)-1-phenyl-1H-pyrazole
Molbank, 2021 A new fluorinated pyrazole, 5-(4-fluorophenyl)-3-(naphthalen-1-yl)-1-phenyl-1H-pyrazole was successfully synthesized via a two-step reaction. Firstly, the synthesis of pyrazoline was performed via one-pot three-component reaction under microwave ...
Jasril Jasril +5 more
doaj +1 more source
Antimony(III) Chloride Catalyzed Direct Three Component One-pot Mannich Reaction
Natural Product Communications, 2009 Antimony(III) chloride catalyzes the three component Mannich type reaction of a variety of in-situ generated Schiff bases generated from aromatic aldehydes and anilines with cyclic/acyclic ketones. The reaction proceeds smoothly at ambient temperature to
Prashant Shukla +2 more
doaj +1 more source
Three-Component Aminoselenation of Arynes [PDF]
, 2019 The three-component coupling of tertiary amines, arynes, and aryl selenium bromide or diaryl diselenide as an electrophilic selenium source allowing the synthesis of 2-selanyl aniline derivatives is reported.
Rahul N. Gaykar (5536235) +3 more
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Microwave-assisted three-component domino reaction: Synthesis of indolodiazepinotriazoles
Beilstein Journal of Organic Chemistry, 2013 A microwave-assisted three-component protocol involving N-1 alkylation of 2-alkynylindoles with epichlorohydrin, ring opening of the epoxide with sodium azide, and an intramolecular Huisgen azide–internal alkyne 1,3-dipolar cycloaddition domino sequence ...
Rajesh K. Arigela +3 more
doaj +1 more source
Benzannulated Bicycles by Three‐Component Aryne Reactions
Angewandte Chemie International Edition, 2011 Triple crown: A pair of three-component coupling reactions between arynes, isocyanides, and either activated alkynes or phenyl esters generates unusual iminoindenones or phenoxy iminoisobenzofurans (see scheme), the latter of which may be advanced to o-ketobenzamides by performing direct hydrolysis.
Allan, Kevin M. +2 more
openaire +3 more sources
Green Chemistry Letters and Reviews, 2023 As an important class of natural products, pyrazole alkaloids have a large number of applications in various aspects such as medicines and pesticides. Due to the special position of its amino group, 3-aminopyrazole is easy to form a hydrogen bond donor ...
Zilin Gao +9 more
doaj +1 more source