Results 41 to 50 of about 16,937,278 (294)

Hf(OTf)₄-Catalyzed Three-Component Synthesis of N-Carbamate-Protected β-Amino Ketones

Molecules, 2022
Hafnium(IV) triflate (Hf(OTf)4) has been identified as a potent catalyst for the direct three-component synthesis of β-carbamate ketones. This new method, featuring a low catalyst loading, fast reaction rate, and solvent-free conditions, provided facile ...
Zhen-Zhen Chen, Dong-Zhao Yang, Ying-Ying Dong, Mei Chi, Shou-Zhi Pu, Qi Sun   +5 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

A Scalable Approach to Primary Amines via the Petasis Reaction

Журнал органічної та фармацевтичної хімії
The efficient and scalable synthesis of homoallylic amines is a subject of significant interest due to the potential applications of these compounds in medicinal and synthetic chemistry.
Serhiy V. Ryabukhin, Maksym V. Herasymchuk   +1 more
doaj   +1 more source

EXTRACT OF BARBERRY AS ENTIRELY GREEN CATALYST FOR THE SYNTHESIS OF STRUCTURALLY DIVERSE 3,4,5-SUBSTITUTED FURAN-2(5H)-ONES [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2016
An eco-friendly and environmentally benign synthesis of 3,4,5-substituted furan-2(5H)-ones employing Iranian seedless barberry, known as Zereshk, (Berberis integerrima “Bidaneh”, Berberidaceae) as a biocatalyst, was developed.
Nourallah Hazeri, Razieh Doostmohammadi, Belgheis Adrom, Mojtaba Lashkari, Malek Taher Maghsoodlou   +4 more
doaj   +1 more source

Crystal structure of 4-(naphthalen-2-yl)-2-oxo-6-phenyl-1,2-dihydropyridine-3-carbonitrile

Acta Crystallographica Section E: Crystallographic Communications, 2023
The synthesis and crystal structure of the title compound, C22H14N2O, are described. The title compound was synthesized by a three-component one-pot reaction in DMSO involving chalcone, cyanoacetamide and elemental sulfur as catalyst.
Thai Thanh Thu Bui, Dinh Hung Mac, Pham Quang Trung, Chien Thang Pham   +3 more
doaj   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source

Synthesis and Biological Evaluation of Aminobisphosphonates—Analogues of Incadronate

Proceedings, 2019
Bisphosphonates had been found to act as strong metal ion complexing agents with usefulindustrial and household applications. [...]
Ewa Chmielewska, Jan Kuryszko, Joanna Wietrzyk, Zdzisław Kiełbowicz, Paweł Kafarski   +4 more
doaj   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Synthesis of polyaromatic derivatives of indenopyrrole and investigation of their absorption and emission behaviors

Results in Chemistry
In this work, new derivatives of 2-methyl-dihydroxyindenopyrrole were synthesized using a three-component reaction between polycyclic aromatic amine (1-aminopyrene or 1-aminonaphthalene), ninhydrin and a β-dicarbonyl in the presence of Lewis acid ...
Maedeh Zolfalizadeh, Zarrin Ghasemi, Somayeh Rashtabad Jadidi, Forough Nasuhipur   +3 more
doaj   +1 more source

Some cyano-substituted spiro-linked pyrazolines and pyrrolidines with antimicrobial activity [PDF]

Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология
This work summarizes one-pot synthetic approaches to spiro-fused (di)azoles, which are promising in terms of studying biological activity. Proposed approaches involve condensation reactions of (hetero)cyclic ketones, methylene active moieties, and N ...
Meshcheryakova, Anna A., Borisova, Svetlana Vasilievna, Konstantinova, Ekaterina A., Vidlatskaya, Daria V., Burygin, Gennady L., Sorokin, Vitaly Viktorovich   +5 more
doaj   +1 more source