Results 41 to 50 of about 1,083,524 (297)

Facile Three-Component Synthesis, Insecticidal and Antifungal Evaluation of Novel Dihydropyridine Derivatives

Molecules, 2018
In an attempt to find the neonicotinoid insecticides, twenty novel dihydropyridine derivatives were designed, “green” synthesized via one pot facile three-component reaction and evaluated for their bioactivities against Tetranychus ...
Guan-Zhou Yang, Xiao-Fei Shang, Pi-Le Cheng, Xiao-Dan Yin, Jia-Kai Zhu, Ying-Qian Liu, Jing Zhang, Zhi-Jun Zhang   +7 more
doaj   +1 more source

EXTRACT OF BARBERRY AS ENTIRELY GREEN CATALYST FOR THE SYNTHESIS OF STRUCTURALLY DIVERSE 3,4,5-SUBSTITUTED FURAN-2(5H)-ONES [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2016
An eco-friendly and environmentally benign synthesis of 3,4,5-substituted furan-2(5H)-ones employing Iranian seedless barberry, known as Zereshk, (Berberis integerrima “Bidaneh”, Berberidaceae) as a biocatalyst, was developed.
Nourallah Hazeri, Razieh Doostmohammadi, Belgheis Adrom, Mojtaba Lashkari, Malek Taher Maghsoodlou   +4 more
doaj   +1 more source

Hf(OTf)₄-Catalyzed Three-Component Synthesis of N-Carbamate-Protected β-Amino Ketones

Molecules, 2022
Hafnium(IV) triflate (Hf(OTf)4) has been identified as a potent catalyst for the direct three-component synthesis of β-carbamate ketones. This new method, featuring a low catalyst loading, fast reaction rate, and solvent-free conditions, provided facile ...
Zhen-Zhen Chen, Dong-Zhao Yang, Ying-Ying Dong, Mei Chi, Shou-Zhi Pu, Qi Sun   +5 more
doaj   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source

Enantioselective Organocatalytic Three-Component Petasis Reaction among Salicylaldehydes, Amines, and Organoboronic Acids [PDF]

, 2012
The catalytic enantioselective three-component Petasis reaction among salicylaldehydes, amines, and organoboronic acids with a newly designed thiourea-binol catalyst is presented. A broad range of alkylaminophenols can be obtained in good yield (up to 92%
Yuan, Wei-Cheng, Han, Wen-Yong, Zhang, Xiao-Mei, Wu, Zhi-Jun, Yuan, WC (reprint author), Chinese Acad Sci, Natl Engn Res Ctr Chiral Drugs, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China.   +4 more
core  

Crystal structure of 4-(naphthalen-2-yl)-2-oxo-6-phenyl-1,2-dihydropyridine-3-carbonitrile

Acta Crystallographica Section E: Crystallographic Communications, 2023
The synthesis and crystal structure of the title compound, C22H14N2O, are described. The title compound was synthesized by a three-component one-pot reaction in DMSO involving chalcone, cyanoacetamide and elemental sulfur as catalyst.
Thai Thanh Thu Bui, Dinh Hung Mac, Pham Quang Trung, Chien Thang Pham   +3 more
doaj   +1 more source

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

NbCl5-catalyzed one-pot Mannich-type reaction: three component synthesis of beta-amino carbonyl compounds [PDF]

, 2007
Three-component Mannich-type reaction of acetophenone, aromatic aldehydes and aromatic amines was catalyzed by NbCl5 at ambient temperature to give various P-amino ketones in high yields, (c) 2007 Elsevier Ltd.
Huang, TK, Lu, XX, Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China., Shi, L, Lu, XX, Wang, R, Li, BG   +5 more
core  

Predicting Three-Component Reaction Outcomes from 40k Miniaturized Reactant Combinations [PDF]

Efficient drug discovery relies on accessing diverse small molecules expediently and reliably. Improvements to reliability through machine learning predictions are hampered by poor availability of high-quality reaction data.
Yu, Takahashi, Iain, Stepek, Julian, Götz, Louis, Bertschi, Bertran, Rubi, Euan, Richards, Yi-Lin, Huang, Jeffrey, Bode   +7 more
core   +1 more source

One-Pot Three-Component Tandem Metathesis/Diels−Alder Reaction [PDF]

, 2016
A tandem enyne, diene-ene metathesis reaction followed by Diels−Alder reaction accomplished a stereoselective three-component reaction protocol with four ...
Hee-Yoon Lee (165448), Hyunsup Tae (3067446), Hyoun Young Kim (3067449), Jaeyoung Lee (786499), Byung Gyu Kim (1484434)   +4 more
core   +1 more source