Results 51 to 60 of about 1,083,524 (297)

A Scalable Approach to Primary Amines via the Petasis Reaction

Журнал органічної та фармацевтичної хімії
The efficient and scalable synthesis of homoallylic amines is a subject of significant interest due to the potential applications of these compounds in medicinal and synthetic chemistry.
Serhiy V. Ryabukhin, Maksym V. Herasymchuk   +1 more
doaj   +1 more source

Phase Angle as an Early Functional Biomarker of Cancer‐Related Fatigue in Pediatric Oncology: A Prospective Longitudinal Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior, Luiz Claudio Barreto Silva Neto, Fabiano Kenji Haraguchi, Letícia Batista de Azevedo, Marcelo Brenner Nascimento Carlini, Raphael Manhães Pessanha, Mariana Rabello Laignier, Wesley Rocha Grippa, Tania Mara Lopes Bitti Bortolini, Gláucia Zouain‐Figueiredo, Regina Aparecida Garcia de Lima, Liliana Vasquez   +11 more
wiley   +1 more source

Multicomponent Reaction Discovery: Three-Component Synthesis of Spirooxindoles [PDF]

, 2016
The Lewis acid-catalyzed, three-component reaction of isatin and two 1,3-dicarbonyl compounds is reported. Reactions proceed with high efficiency under mild reaction conditions and with good functional group tolerance to afford spirooxindole ...
John A. Porco (1307085), Srinivas Kalidindi (2321008), Bo Liang (450389), Corey R. J. Stephenson (1328196)   +3 more
core   +5 more sources

Synthesis and Biological Evaluation of Aminobisphosphonates—Analogues of Incadronate

Proceedings, 2019
Bisphosphonates had been found to act as strong metal ion complexing agents with usefulindustrial and household applications. [...]
Ewa Chmielewska, Jan Kuryszko, Joanna Wietrzyk, Zdzisław Kiełbowicz, Paweł Kafarski   +4 more
doaj   +1 more source

Multicomponent Reaction Discovery: Three-Component Synthesis of Spirooxindoles [PDF]

Organic Letters, 2010
The Lewis acid-catalyzed, three-component reaction of isatin and two 1,3-dicarbonyl compounds is reported. Reactions proceed with high efficiency under mild reaction conditions and with good functional group tolerance to afford spirooxindole pyranochromenedione derivatives.
Bo, Liang, Srinivas, Kalidindi, John A, Porco, Corey R J, Stephenson   +3 more
openaire   +2 more sources

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Palladium-Catalyzed Three-Component Selective Aminoallylation of Diazo Compounds [PDF]

, 2022
In spite of the valuable perspective on rapid accessing α,α-disubstituted α-amino acid derivatives, a three-component reaction of diazo compounds, amines and allyl esters remains as an unexplored challenge, probably because of the fore-seeable side ...
Pengcheng, Ou, Lei, Zhu, Yinghua, Yu, Liyao, Ma, Xueliang, Huang   +4 more
core   +1 more source

Synthesis of polyaromatic derivatives of indenopyrrole and investigation of their absorption and emission behaviors

Results in Chemistry
In this work, new derivatives of 2-methyl-dihydroxyindenopyrrole were synthesized using a three-component reaction between polycyclic aromatic amine (1-aminopyrene or 1-aminonaphthalene), ninhydrin and a β-dicarbonyl in the presence of Lewis acid ...
Maedeh Zolfalizadeh, Zarrin Ghasemi, Somayeh Rashtabad Jadidi, Forough Nasuhipur   +3 more
doaj   +1 more source

Some cyano-substituted spiro-linked pyrazolines and pyrrolidines with antimicrobial activity [PDF]

Известия Саратовского университета. Новая серия: Серия Химия. Биология. Экология
This work summarizes one-pot synthetic approaches to spiro-fused (di)azoles, which are promising in terms of studying biological activity. Proposed approaches involve condensation reactions of (hetero)cyclic ketones, methylene active moieties, and N ...
Meshcheryakova, Anna A., Borisova, Svetlana Vasilievna, Konstantinova, Ekaterina A., Vidlatskaya, Daria V., Burygin, Gennady L., Sorokin, Vitaly Viktorovich   +5 more
doaj   +1 more source

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley, Ryleigh Krueger, Kellie Joyce, James Stanley, Mary Waskerwitz‐Freyer, Marielle Klunder, David J. Hoogstra   +6 more
wiley   +1 more source