Mimicking Epithelial Tissues in Three-Dimensional Cell Culture Models
Frontiers in Bioengineering and Biotechnology, 2018 Epithelial tissues are composed of layers of tightly connected cells shaped into complex three-dimensional (3D) structures such as cysts, tubules, or invaginations.
Núria Torras +5 more
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Three-Dimensional Cell Culture Systems in Radiopharmaceutical Cancer Research. [PDF]
Cancers (Basel), 2020 Simple Summary Cancer cells cultured in three-dimensional (3D) model systems exhibit physiologically relevant cell–cell and cell–matrix interactions, gene expression patterns, and signaling cascades as well as heterogeneity and structural complexity that
Doctor A +4 more
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Three-Dimensional Cell Culture: A Breakthrough in Vivo [PDF]
International Journal of Molecular Sciences, 2015 Cell culture is an important tool for biological research. Two-dimensional cell culture has been used for some time now, but growing cells in flat layers on plastic surfaces does not accurately model the in vivo state.
D. Antoni +3 more
semanticscholar +3 more sources
Three Dimensional Culture of Human Renal Cell Carcinoma Organoids. [PDF]
PLoS ONE, 2015 Renal cell carcinomas arise from the nephron but are heterogeneous in disease biology, clinical behavior, prognosis, and response to systemic therapy. Development of patient-specific in vitro models that efficiently and faithfully reproduce the in vivo ...
Cynthia A Batchelder +4 more
doaj +6 more sources
Biopolymer-Based Microcarriers for Three-Dimensional Cell Culture and Engineered Tissue Formation. [PDF]
Int J Mol Sci, 2020 The concept of three-dimensional (3D) cell culture has been proposed to maintain cellular morphology and function as in vivo. Among different approaches for 3D cell culture, microcarrier technology provides a promising tool for cell adhesion ...
Huang L, Abdalla AME, Xiao L, Yang G.
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Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modeling. [PDF]
World J Stem Cells, 2019 Three-dimensional (3D) culture systems are becoming increasingly popular due to their ability to mimic tissue-like structures more effectively than the monolayer cultures.
Chaicharoenaudomrung N +2 more
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Characterization of an Aggregated Three-Dimensional Cell Culture Model by Multimodal Mass Spectrometry Imaging. [PDF]
Anal Chem, 2020 Mass spectrometry imaging (MSI) is an established analytical tool capable of defining and understanding complex tissues by determining the spatial distribution of biological molecules.
Flint LE +9 more
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Three-Dimensional Cell Culture Models to Investigate Oral Carcinogenesis: A Scoping Review. [PDF]
Int J Mol Sci, 2020 Three-dimensional (3-D) cell culture models, such as spheroids, organoids, and organotypic cultures, are more physiologically representative of the human tumor microenvironment (TME) than traditional two-dimensional (2-D) cell culture models.
Chitturi Suryaprakash RT +3 more
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Thermosensitive polymeric matrices for three-dimensional cell culture strategies [PDF]
Acta Biomaterialia, 2011 A completely new strategy for cell culture focusing on the design of three-dimensional (3D) smart surfaces by supercritical fluid technology has been developed. This approach might overcome the limitations on cell expansion and proliferation of currently
Duarte, Ana Rita C. +2 more
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Editorial: Three-dimensional/3D stem cell culture systems
Frontiers in Cell and Developmental Biology, 2023 Katiucia Batista Silva Paiva +7 more
doaj +3 more sources