Results 31 to 40 of about 828,765 (377)
Biomedicines, 2022 Ovarian cancer (OC) is the leading cause of death from gynecological malignancies. Despite great advances in treatment strategies, therapeutic resistance and the gap between preclinical data and actual clinical efficacy justify the necessity of ...
Iason Psilopatis +4 more
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Three-Dimensional Cell Cultures in Toxicology [PDF]
Biotechnology and Genetic Engineering Reviews, 2009 Toxicity testing with animals is expensive, ethically controversial, and not always predictive of the human response. Cell-based assays are regarded as an alternative. However, conventional two-dimensional cell cultures do not reproduce the tissue architecture in vivo, and do not forecast organ-specific toxicity.
Francesco, Pampaloni, Ernst, Stelzer
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Recent Advances in Three-Dimensional Stem Cell Culture Systems and Applications
Stem Cells International, 2021 Cell culture is one of the most core and fundamental techniques employed in the fields of biology and medicine. At present, although the two-dimensional cell culture method is commonly used in vitro, it is quite different from the cell growth ...
Xiaowen Wu +4 more
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Three-dimensional cell culture technique and pathophysiology [PDF]
Advanced Drug Delivery Reviews, 2014 Three-dimensional (3D) tissue constructs consisting of human cells have opened a new avenue for tissue engineering, pharmaceutical and pathophysiological applications, and have great potential to estimate the dynamic pharmacological effects of drug candidates, metastasis processes of cancer cells, and toxicity expression of nano-materials, as a 3D ...
Michiya, Matsusaki +2 more
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Investigating the Role of Surface Materials and Three Dimensional Architecture on In Vitro Differentiation of Porcine Monocyte-Derived Dendritic Cells [PDF]
, 2016 In vitro generation of dendritic-like cells through differentiation of peripheral blood monocytes is typically done using two-dimensional polystyrene culture plates.
Brogaard, Louise +8 more
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Three-dimensional human airway epithelial cell cultures [PDF]
Journal of Cystic Fibrosis, 2004 An epithelial airway-derived 3-D cell culture model is described. The long lifetime of this model, compared to monolayer cultures of primary cells, allows many experiments with material from one single patient to be performed.
Ulrich, M., Döring, G.
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Mxi1 influences cyst formation in three-dimensional cell culture [PDF]
BMB Reports, 2012 Cyst formation is a major characteristic of ADPKD and iscaused by the abnormal proliferation of epithelial cells. Renalcyst formation disrupts renal function and induces diversecomplications.
Yeon Joo Yook +9 more
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Three-dimensional culture may promote cell reprogramming [PDF]
Organogenesis, 2013 Stem cells reside in stem cells niches, which maintain the balance of self-renewal and differentiation of stem cells. In stem cell niches, cell-cell, cell-extracellular matrix interactions and diffusible signals are important elements. However, another pivotal element is that localized and diffusible signals are all organized as three-dimensional (3-D)
Jin, Han +5 more
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Three dimensional microcarrier system in mesenchymal stem cell culture: a systematic review
Cell & Bioscience, 2020 Stem cell-based regenerative medicine is a promising approach for tissue reconstruction. However, a large number of cells are needed in a typical clinical study, where conventional monolayer cultures might pose a limitation for scale-up.
Benson Koh +6 more
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Current Approaches to Three-Dimensional Cell Culture System
Namık Kemal Tıp Dergisi, 2020 Two-dimensional (2D) cell culture is a valuable method for cell-based research, However, it may provide unpredictable, misleading data on in vivo responses.
Elif POLAT
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