Results 61 to 70 of about 828,765 (377)
Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. [PDF]
, 2015 Exposure to high levels of ionizing radiation (IR) leads to debilitating and dose-limiting gastrointestinal (GI) toxicity. Using three-dimensional mouse crypt culture, we demonstrated that p53 target PUMA mediates radiation-induced apoptosis via a cell ...
Cramer, Julie M +14 more
core +2 more sources
A High-Throughput and Uniform Amplification Method for Cell Spheroids
Micromachines, 2022 Cell culture is an important life science technology. Compared with the traditional two-dimensional cell culture, three-dimensional cell culture can simulate the natural environment and structure specificity of cell growth in vivo. As such, it has become
Liyuan Liu +4 more
doaj +1 more source
Magnetically levitated mesenchymal stem cell spheroids cultured with a collagen gel maintain phenotype and quiescence [PDF]
, 2017 Multicellular spheroids are an established system for three-dimensional cell culture. Spheroids are typically generated using hanging drop or non-adherent culture; however, an emerging technique is to use magnetic levitation.
Berry, Catherine C. +5 more
core +2 more sources
In vitro three-dimensional cell cultures for bone sarcomas
Journal of Bone Oncology, 2021 Bone sarcomas are rare tumour entities that arise from the mesenchyme most of which are highly heterogeneous at the cellular, genetic and epigenetic levels. The three main types are osteosarcoma, Ewing sarcoma, and chondrosarcoma. These oncological entities are characterised by high morbidity and mortality and an absence of significant therapeutic ...
Muñoz-Garcia, Javier +7 more
openaire +4 more sources
Scaffold-free three-dimensional cell culture utilizing micromolded nonadhesive hydrogels
BioTechniques, 2007 Techniques that allow cells to self-assemble into three-dimensional (3-D) spheroid microtissues provide powerful in vitro models that are becoming increasingly popular—especially in fields such as stem cell research, tissue engineering, and cancer ...
Anthony P. Napolitano +7 more
doaj +1 more source
3D Cell Culture in a Self-Assembled Nanofiber Environment. [PDF]
PLoS ONE, 2016 The development and utilization of three-dimensional cell culture platforms has been gaining more traction. Three-dimensional culture platforms are capable of mimicking in vivo microenvironments, which provide greater physiological relevance in ...
Yi Wen Chai +3 more
doaj +1 more source
A Preliminary Study on Using Multi-Nozzle Polymer Deposition System to Fabricate Composite Alginate/Carbon Nanotube Tissue Scaffolds [PDF]
, 2006 Three-dimensional composite alginate/single wall carbon nanotube (SWCNT) scaffolds encapsulated with endothelial cells were fabricated by a multi-nozzle biopolymer freeform deposition system.
Guceri, S. +3 more
core +1 more source
BioSig3D: High Content Screening of Three-Dimensional Cell Culture Models.
PLoS ONE, 2016 BioSig3D is a computational platform for high-content screening of three-dimensional (3D) cell culture models that are imaged in full 3D volume. It provides an end-to-end solution for designing high content screening assays, based on colony organization ...
Cemal Cagatay Bilgin +5 more
doaj +1 more source
Applied Sciences, 2023 The characteristics of 3-dimensional (3D) cultured periodontal ligament stem cells derived from permanent teeth (pPDLSCs) and supernumerary teeth (sPDLSCs) were compared and evaluated in this study.
Heejin Kim +7 more
doaj +1 more source
, 2019 Here, using an integrative experimental and computational approach, Imle et al. show how cell motility and density affect HIV cell-associated transmission in a three-dimensional tissue-like culture system of CD4+ T cells and collagen, and how different ...
Ales, J. +14 more
core +2 more sources