Results 81 to 90 of about 20,905,469 (291)
Brazilian Journal of Medical and Biological Research, 2005 Cell fate decisions are governed by a complex interplay between cell-autonomous signals and stimuli from the surrounding tissue. In vivo cells are connected to their neighbors and to the extracellular matrix forming a complex three-dimensional (3-D ...
M.I.D. Rossi +8 more
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Editorial: Three-dimensional/3D stem cell culture systems
Frontiers in Cell and Developmental Biology, 2023 Katiucia Batista Silva Paiva +7 more
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Preconditioned Cell Array Optimized for a Three-Dimensional Culture of Hepatocytes
Cell Transplantation, 2009 Three-dimensional culture procedures have attracted attention in various fields of cell biology. A newly developed cell array assisted in the formation of hepatocyte spheroids by two innovations: 1) micropatterning by a hydrophilic polymer, and 2) the ...
Yoshitaka Miyamoto +2 more
doaj +1 more source
Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins
BMC Cancer, 2018 Background Cancer cell resistance to therapeutics can result from acquired or de novo-mediated factors. Here, we have utilised advanced breast cancer cell culture models to elucidate de novo doxorubicin resistance mechanisms.
Carrie J. Lovitt +2 more
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Chapter 5 Three-Dimensional culture for Expansion and Differentiation of Embryonic Stem Cells
, 2011 Chapter 5 Three-Dimensional culture for Expansion and Differentiation of Embryonic Stem ...
待补充 +5 more
core
, 2010 The aim of the study was to investigate whether changes in the pattern of gene copy number and cell cycle were present passing from the two- to the three-dimensional cell culture system.
M.T. Bardella +8 more
core +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Functional validation of cancer stem cell markers in primary human colorectal cancer and established cell lines [PDF]
, 2014 In an increasing number of cancers, CSCs have been defined on the basis of the self-renewal and tumor initiation capacity by functional assays. It has been also suggested that CSC populations might be responsible for chemo- and radio-therapy resistance ...
Muraro, Manuele Giuseppe
core +1 more source