Results 121 to 130 of about 308,830 (401)
Advanced Science, EarlyView.Ultrasound (US)‐treated nanocomposite ‘lever’ hydrogels reprogrammed wound reactive oxygen species (ROS) levels and promoted wound healing in infected diabetic foot ulcers. Abstract Diabetic foot ulcers (DFUs) are a complex mixture of neuropathy, peripheral arterial disease, and infection, where excessive reactive oxygen species (ROS) exacerbates ...
Yuting Shen +16 more
wiley +1 more source
Journal of molecular medicine, 2013 Thrombin is the protease involved in blood coagulation. Its deregulation can lead to hemostatic abnormalities, which range from subtle subclinical to serious life-threatening coagulopathies, i.e., during septicemia. Additionally, thrombin plays important
S. Danckwardt, M. Hentze, A. Kulozik
semanticscholar +1 more source
Percutaneous Thrombin Injection for the Treatment of Post-Procedural Iatrogenic Pseudoaneurysms
대한영상의학회지, 2019 Purpose To report our clinical experience of thrombin injection for iatrogenic pseudoaneurysms of peripheral arteries with or without balloon dilatation and coil embolization as adjunctive techniques.
Sohee Park +5 more
doaj +1 more source
Cells, 2019 The aim of this study was to compare the acute effects of thrombin and brain-derived neurotrophic factor (BDNF) on spontaneous miniature endplate potentials (MEPPs) and multiquantal evoked endplate potentials (EPPs) in mouse neuromuscular junctions (NMJs)
Alexander Gaydukov +6 more
doaj +1 more source
Galpha 12 and Galpha 13 Are Phosphorylated during Platelet Activation [PDF]
, 1996 The ubiquitously expressed G-proteins G12 and G13 whose function is currently not clear have been shown to be activated in platelet membranes through receptors that stimulate platelet aggregation. We used intact human platelets to determine whether alpha
Hu, Yi-Hui +2 more
core
Advanced Science, EarlyView.3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang +17 more
wiley +1 more source
Journal of Biological Chemistry, 2013 Background: Thrombin-cleaved PAR1 reveals a tethered ligand that can transactivate PAR2. Results: The thrombin-activated PAR1-PAR2 heterodimer displays unique trafficking behavior, recruitment of β-arrestins to endosomes, and signaling responses compared
Huilan Lin, J. Trejo
semanticscholar +1 more source
Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis
Advanced Science, EarlyView.In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li +6 more
wiley +1 more source
Thrombin inhibitory activity of some polyphenolic compounds
Medicinal Chemistry Research, 2013 Thrombin, also known as an active plasma coagulation factor II, belongs to the family of serine proteases and plays a crucial role in blood coagulation process.
M. Bijak +7 more
semanticscholar +1 more source
Src kinase inhibition decreases thrombin-induced injury and cell cycle re-entry in striatal neurons
Neurobiology of Disease, 2008 Since Src kinase inhibitors decrease brain injury produced by intracerebral hemorrhage (ICH) and thrombin is activated following ICH, this study determined whether Src kinase inhibitors decrease thrombin-induced brain injury.
Da-Zhi Liu +6 more
doaj