Abstract Purpose Treating large cartilage lesions in the knee remains a challenge. While matrix‐associated autologous chondrocyte implantation (MACI) is the gold standard for medium to large lesions, the minced cartilage technique has shown promise in smaller defects. Enhancing this technique with biomaterials has been suggested for larger lesions, but
Johanna Mayr +5 more
wiley +1 more source
The Role of Surfactants in Stabilizing Fluorescence Anisotropy for Protein-Aptamer Binding Affinity Measurements. [PDF]
Samarakoon BR, Bilderback SL, Whelan RJ.
europepmc +1 more source
Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Thrombin generation in HeartMate 3 patients on apixaban and vitamin K antagonists: Variability limits clinical applicability. [PDF]
Van Edom CJ +9 more
europepmc +1 more source
Thrombin Augments LPS‐Induced Human Endometrial Endothelial Cell Inflammation via PAR1 Activation
Mohak Mhatre +4 more
openalex +2 more sources
Thrombin Causes a Marked Delay in Skeletal Myogenesis That Correlates with the Delayed Expression of Myogenin and p21 [PDF]
Denis C. Guttridge +3 more
openalex +1 more source
Glycoprotein Ib activation by thrombin stimulates the energy metabolism in human platelets [PDF]
Corona de la Pena, Norma +4 more
core +3 more sources
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri +2 more
wiley +1 more source
Exploratory Analysis of Coagulation and Fibrinolysis Trajectories After IL-6 Antagonist Therapy in COVID-19: A Case Series. [PDF]
Kovács EH +13 more
europepmc +1 more source

