Results 71 to 80 of about 243,553 (260)
Research and Practice in Thrombosis and Haemostasis, 2020 Combined oral contraceptives and factor V Leiden mutation are multiplicative risk factors for venous thromboembolism. However, it remains unknown whether this multiplicative effect is reflected in thrombin generation assays.
Maxime G. Zermatten +3 more
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Coagulation and anticoagulation in idiopathic pulmonary fibrosis [PDF]
, 2015 Idiopathic pulmonary fibrosis (IPF) is an incurable, progressive interstitial lung disease with a prognosis that is worse than that of many cancers. Epidemiological studies have demonstrated a link between IPF and thrombotic vascular events.
Crooks, Michael G., Hart, Simon P.
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Oxidative stress model of lipopolysaccharide combined with thrombin inducing in broiler chicks
Frontiers in Veterinary ScienceLipopolysaccharides (LPS) are commonly used to construct inflammation models. However, poultry have a certain degree of tolerance to LPS due to the lack of thrombin XI and XII in their bodies. Thrombin activation produces clotting factors that can cleave
Huiyu Shi +10 more
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Frontiers in Immunology, 2018 BackgroundThe interaction of coagulation factors has been shown to go beyond their traditional roles in hemostasis and to affect the development of inflammatory diseases.
Kerstin Göbel +5 more
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DiagnosticsBackground. Alterations induced by direct oral anticoagulants (DOACs) or vitamin K antagonists (VKAs) to thromboelastometry and thrombin generation are not well defined.
Armando Tripodi +8 more
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Research in Molecular Medicine, 2021 Background: Recombinant insulin glargine, a long-acting analog of insulin, is expressed as proinsulin in the host cell and, after purification and refolding steps, is processed to mature insulin by using trypsin and carboxypeptidase B. Because of several
Seyyedeh khadijeh Hosseini oula +2 more
doaj
Participation of the hypophyseal-adrenal cortex system in thrombin clearance during immobilization stress [PDF]
Thrombin marked with I-131 resulted in a considerable increase of the thrombined clearance rate in healthy male rats during stress caused by an immobilization lasting 30 minutes, and in an increase of thrombin clearance occurred by a combination of ...
Bazazyan, G. G. +3 more
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Scalable and Accurate Online Feature Selection for Big Data
, 2016 Feature selection is important in many big data applications. Two critical challenges closely associate with big data. Firstly, in many big data applications, the dimensionality is extremely high, in millions, and keeps growing.
Ding, Wei +3 more
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Endothelial protease-activated receptor 4: impotent or important?
Frontiers in Cardiovascular MedicineThe protease thrombin, which increases its levels with various pathologies, can signal through the G protein-coupled receptors protease-activated receptors 1 and 4 (PAR1/PAR4). PAR1 is a high-affinity receptor for thrombin, whereas PAR4 is a low-affinity
Rahul Rajala +4 more
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Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor. [PDF]
, 1992 We recently isolated a cDNA clone encoding a functional platelet thrombin receptor that defined a unique mechanism of receptor activation. Thrombin cleaves its receptor's extracellular amino terminal extension, unmasking a new amino terminus that ...
Coughlin, SR +3 more
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