Results 221 to 230 of about 18,386 (273)

Ribosomal Proteins in Cell Biology and Cancer

MedComm – Oncology, Volume 5, Issue 2, June 2026.
The functions of ribosomal proteins (RPs) extend beyond the conventional translation process, as they also regulate gene expression, stress responses, and disease progression. Dysregulation of RPs contributes to the onset and progression of various diseases, including cancer and ribosomopathies, underscoring their dual role as critical disease ...
Ao Zhang, Zeguang Sun, Xinyang Song, Xikun Zhou, Jing Li   +4 more
wiley   +1 more source

Human Protein Z as the Second Known Heme-Binding Protein from the Endogenous Blood Coagulation Inhibitor System. [PDF]

Chembiochem
Lindemann P, Hopp MT.
europepmc   +1 more source

Optimizing Venous Thromboembolism Prophylaxis in Burn Patients Using Enoxaparin Through PBPK Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 6, June 2026.
ABSTRACT Burn injuries cause physiological changes that alter enoxaparin pharmacokinetics, often leading to inadequate exposure and suboptimal venous thromboembolism (VTE) prophylaxis. Current weight‐based dosing and anti‐Xa monitoring provide limited guidance for dose optimization across burn severities.
Sabiha Rahman Mim, Venkata K. Yellepeddi, Francine J. Azeredo   +2 more
wiley   +1 more source

Ursodeoxycholic acid mitigates cerebral ischemia/reperfusion injury by inhibiting thrombin-induced lipid peroxidation through activation of ALDH3A1. [PDF]

Redox Biol
Liu A, Yang T, Li Z, Luo R, Zhu C, Du S, Chen W, Duan J.   +7 more
europepmc   +1 more source

Dynamic Switchable and Transient DNA Condensates Driven by Aptamer‐Ligand or Ion‐Nucleobase Bridged Complexes

Small, Volume 22, Issue 31, 2 June 2026.
Switchable or transient formation and dissociation of the phase‐separated DNA microdroplets generated by metal ions or aptamer‐ligand complexes crosslinking Y‐shaped DNA frameworks and dynamically separated by counter ligands eliminating the bridging metal ions or biocatalysts degrading the aptamer‐ligand complexes, are introduced.
Yichen Han, Yang Sung Sohn, Rachel Nechushtai, Fan Xia, Fujian Huang, Yunlong Qin, Itamar Willner   +6 more
wiley   +1 more source

Computational analysis of the structural and functional impact of the deleterious nsSNPs in the human <i>F2R</i> gene and their implications in glioma. [PDF]

Biochem Biophys Rep
Arosh SM, Hosen MR, Hosen MI, Rahman A.
europepmc   +1 more source

Dual‐Network Reconfigurable Powder Adhesive With Bidirectional Synergy: Concurrent Reinforcement of Tissue Sealing and Coagulation for Hemostatic Tissue Repair

Small Structures, Volume 7, Issue 6, June 2026.
A mechano‐adaptive dual‐network powder adhesive integrates a reconfigurable polyelectrolyte matrix with a thrombin‐activated fibrin network, enabling ultrafast self‐gelation, robust sealing (180.7 mmHg), and bidirectional procoagulant/prohealing synergy.
Wei Zhang, Huarong Shao, Lanqing Wang, Zhaofan Yang, Yuanzhen Su, Guanyu Jin, Xiuhua Zhang, Peixue Ling, Liwei Mi, Shixian Lv, Fei Liu   +10 more
wiley   +1 more source

Discovery and optimization of marstacimab, a human monoclonal antibody targeting tissue factor pathway inhibitor for the treatment of hemophilia A and B. [PDF]

MAbs
Jin M, Hett S, Jasuja R, Rakhe S, Narula J, Tam A, Apgar JR, Juo ZS, Mosyak L, Holsti M, Joyce A, Hurst S, Webster R, Lin L, Stahl M, Pittman DD, Bloom L.   +16 more
europepmc   +1 more source

Higher sensitivity to ouabain‐induced toxicity in human induced pluripotent stem cell‐derived cardiomyocytes than human adult heart tissue despite similar Na+/K+‐ATPase pump current amplitudes

British Journal of Pharmacology, Volume 183, Issue 11, Page 3093-3110, June 2026.
Abstract Background and Purpose Human induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CM) have gained interest as a pharmacological model but their immaturity leads to uncertainty regarding translation. We studied the key player in maintaining ionic homeostasis, the Na+/K+‐ATPase (NKA), in hiPSC‐CM.
Djemail Ismaili, Paavo Virtanen, Junsoo Im, Paul Brunnbauer, Umber Saleem, Muhammed Ikbal Sönmez, Carl Schulz, Margaret Nandudu, Joris Winters, Cristina E. Molina, Johannes Petersen, Monika Stoll, Ulrich Schotten, Arne Hansen, Thomas Eschenhagen, Jussi T. Koivumäki, Torsten Christ   +16 more
wiley   +1 more source

Fibrin Gel as a Versatile Biomaterial Platform in the Biomedical Landscape: Chemical, Physical, and Biological Insights. [PDF]

Gels
Caria S, Petiti J, Ruocco G, Mino L, Romeo R, Romeo R, Viada G, Revel L, Picollo F, Chiono V, Divieto C.   +10 more
europepmc   +1 more source