Results 291 to 300 of about 100,897 (348)
Beyond lipids: Systemic effects of lipoprotein apheresis
Transfusion, EarlyView.
Menatalla Nadim, Yamac Akgun
wiley +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Two cases of Factor XI deficiency: Use of Thrombin Generation Assays (TGA) to detect a non-bleeding phenotype. [PDF]
Sucker C +3 more
europepmc +1 more source
Levels of procoagulant factors and peak thrombin generation in relation to dementia risk in older adults: The Cardiovascular Health Study. [PDF]
Harrington LB +9 more
europepmc +1 more source
Houston, we have a problem: Coagulation concerns during long‐term spaceflight
Experimental Physiology, EarlyView.
Lewis Fall, Damian M. Bailey
wiley +1 more source
Surviving stabbing: The physiology of knife crime
Experimental Physiology, EarlyView.
Hugh Montgomery, Mike Tipton
wiley +1 more source
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Blood, 1999
We have investigated the influence of alterations in plasma coagulation factor levels between 50% and 150% of their mean values for prothrombin, factor X, factor XI, factor IX, factor VII, factor VIII, factor V, protein C, protein S, antithrombin III (AT-III), and tissue factor pathway inhibitor (TFPI) as well as combinations of extremes, eg, 50 ...
Butenas, S., van't Veer, C., Mann, K. G.
openaire +3 more sources
We have investigated the influence of alterations in plasma coagulation factor levels between 50% and 150% of their mean values for prothrombin, factor X, factor XI, factor IX, factor VII, factor VIII, factor V, protein C, protein S, antithrombin III (AT-III), and tissue factor pathway inhibitor (TFPI) as well as combinations of extremes, eg, 50 ...
Butenas, S., van't Veer, C., Mann, K. G.
openaire +3 more sources
Thrombosis Research, 2011
The recent development of semi-automated methods has revived interest in the thrombin generation test, a global assay that measures the overall tendency of a plasma sample to form thrombin after initiation of coagulation. The thrombin generation curve, which is characterised by a lag phase followed by the formation and subsequent inhibition of thrombin,
Castoldi, Elisabetta, Rosing, Jan
openaire +3 more sources
The recent development of semi-automated methods has revived interest in the thrombin generation test, a global assay that measures the overall tendency of a plasma sample to form thrombin after initiation of coagulation. The thrombin generation curve, which is characterised by a lag phase followed by the formation and subsequent inhibition of thrombin,
Castoldi, Elisabetta, Rosing, Jan
openaire +3 more sources
Thrombin generation: phenotypic quantitation
Journal of Thrombosis and Haemostasis, 2004An individual's ability to generate thrombin following tissue factor stimulus was evaluated in 13 healthy male donors in a 6-month study. Thrombin generation in whole blood collected by phlebotomy, contact pathway suppressed by the presence of 100 micro g mL-1 corn trypsin inhibitor, was initiated by the addition of 5 pm tissue factor/10 nm ...
K E, Brummel-Ziedins +2 more
openaire +2 more sources
2013
Generation of thrombin has been established as the critical process leading to coagulation in vivo. Indeed, ex vivo markers of thrombin generation in patients have been useful in detecting thrombosis, while many standard global clot-time tests of haemostasis in blood or plasma samples are simple endpoint measures of the potential to generate thrombin ...
Leslie R, Berry, Anthony K C, Chan
openaire +2 more sources
Generation of thrombin has been established as the critical process leading to coagulation in vivo. Indeed, ex vivo markers of thrombin generation in patients have been useful in detecting thrombosis, while many standard global clot-time tests of haemostasis in blood or plasma samples are simple endpoint measures of the potential to generate thrombin ...
Leslie R, Berry, Anthony K C, Chan
openaire +2 more sources

