Results 291 to 300 of about 100,897 (348)

Beyond lipids: Systemic effects of lipoprotein apheresis

open access: yes
Transfusion, EarlyView.
Menatalla Nadim, Yamac Akgun
wiley   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

open access: yesFEBS Open Bio, Volume 16, Issue 2, Page 314-330, February 2026.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul   +3 more
wiley   +1 more source

Levels of procoagulant factors and peak thrombin generation in relation to dementia risk in older adults: The Cardiovascular Health Study. [PDF]

open access: yesThromb Res
Harrington LB   +9 more
europepmc   +1 more source

Surviving stabbing: The physiology of knife crime

open access: yes
Experimental Physiology, EarlyView.
Hugh Montgomery, Mike Tipton
wiley   +1 more source

“Normal” Thrombin Generation

Blood, 1999
We have investigated the influence of alterations in plasma coagulation factor levels between 50% and 150% of their mean values for prothrombin, factor X, factor XI, factor IX, factor VII, factor VIII, factor V, protein C, protein S, antithrombin III (AT-III), and tissue factor pathway inhibitor (TFPI) as well as combinations of extremes, eg, 50 ...
Butenas, S., van't Veer, C., Mann, K. G.
openaire   +3 more sources

Thrombin generation tests

Thrombosis Research, 2011
The recent development of semi-automated methods has revived interest in the thrombin generation test, a global assay that measures the overall tendency of a plasma sample to form thrombin after initiation of coagulation. The thrombin generation curve, which is characterised by a lag phase followed by the formation and subsequent inhibition of thrombin,
Castoldi, Elisabetta, Rosing, Jan
openaire   +3 more sources

Thrombin generation: phenotypic quantitation

Journal of Thrombosis and Haemostasis, 2004
An individual's ability to generate thrombin following tissue factor stimulus was evaluated in 13 healthy male donors in a 6-month study. Thrombin generation in whole blood collected by phlebotomy, contact pathway suppressed by the presence of 100 micro g mL-1 corn trypsin inhibitor, was initiated by the addition of 5 pm tissue factor/10 nm ...
K E, Brummel-Ziedins   +2 more
openaire   +2 more sources

Thrombin Generation

2013
Generation of thrombin has been established as the critical process leading to coagulation in vivo. Indeed, ex vivo markers of thrombin generation in patients have been useful in detecting thrombosis, while many standard global clot-time tests of haemostasis in blood or plasma samples are simple endpoint measures of the potential to generate thrombin ...
Leslie R, Berry, Anthony K C, Chan
openaire   +2 more sources

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