Results 71 to 80 of about 3,896,793 (331)

Thrombin generation assays for global evaluation of the hemostatic system: perspectives and limitations

Revista Brasileira de Hematologia e Hemoterapia, 2017
The existing techniques to evaluate hemostasis in clinical laboratories are not sensitive enough to detect hypercoagulable and mild hypocoagulable states.
R. Duarte, C. Ferreira, D. R. Rios, H. Reis, M. Carvalho   +4 more
semanticscholar   +1 more source

Enhanced plasma thrombin generation and MP-induced thrombin generation in patients with high CAC.

, 2016
(A) In patients with high CAC compared to patients with low CAC TATc level as a marker of thrombin generation in plasma were higher. (C) TATc level correlated with CAC Score.
Ralf Westenfeld (309533), Gülsüm Erkilet (2580877), Patric Kröpil (581138), Tobias Zeus (655476), Patrick Horn (47116), Malte Kelm (45981), Christian Heiss (446842), Leon Schurgers (560257), Verena Veulemans (309535)   +8 more
core   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Prothrombin conversion accelerates with increasing age in women but not in men: findings from the Moli-sani Cohort Study

Research and Practice in Thrombosis and Haemostasis
Background: The thrombin dynamics method has been used as an add-on analysis method for the thrombin generation test over the past years to study the balance between pro- and anticoagulant pathways.
Amalia De Curtis, Romy de Laat-Kremers, Simona Costanzo, Augusto Di Castelnuovo, Marisa Ninivaggi, Chiara Cerletti, Giovanni de Gaetano, Maria Benedetta Donati, Licia Iacoviello, Bas de Laat, Licia Iacoviello, Giovanni de Gaetano, Maria Benedetta Donati, Chiara Cerletti, Marialaura Bonaccio, Americo Bonanni, Simona Costanzo, Amalia De Curtis, Augusto Di Castelnuovo, Alessandro Gialluisi, Francesco Gianfagna, Mariarosaria Persichillo, Jos Vermylen, Renzo Pegoraro, Antonio G. Spagnolo, Deodato Assanelli, Livia Rago, Simona Costanzo, Sabatino Orlandi, Teresa Panzera, Augusto Di Castelnuovo, Marialaura Bonaccio, Francesca Bracone, Simona Costanzo, Giuseppe Di Costanzo, Simona Esposito, Alessandro Gialluisi, Anwal Ghulam, Francesco Gianfagna, Martina Morelli, Maria Loreto Muñoz Venegas, Antonietta Pepe, Emilia Ruggiero, Amalia De Curtis, Concetta Civitillo, Alisia Cretella, Sara Magnacca, Mariarosaria Persichillo, Francesca Bracone, Giuseppe Di Costanzo, Martina Morelli, Americo Bonanni   +51 more
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Thrombin generation correlates with disease duration in multiple sclerosis (MS): Novel insights into the MS-associated prothrombotic state

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2017
Background Thrombin is well recognised for its role in the coagulation cascade but it also plays a role in inflammation, with enhanced thrombin generation observed in several inflammatory disorders.
Martin EM Parsons, Karen O’Connell, Seamus Allen, Karl Egan, Paulina B Szklanna, Christopher McGuigan, Fionnuala Ní Áinle, Patricia B Maguire   +7 more
doaj   +1 more source

Antiplatelet agents can promote two-peaked thrombin generation in platelet rich plasma: mechanism and possible applications. [PDF]

PLoS ONE, 2013
BACKGROUND: Thrombin generation assay is a convenient and widely used method for analysis of the blood coagulation system status. Thrombin generation curve (TGC) is usually bell-shaped with a single peak, but there are exceptions.
Ivan D Tarandovskiy, Elena O Artemenko, Mikhail A Panteleev, Elena I Sinauridze, Fazoil I Ataullakhanov   +4 more
doaj   +1 more source

A review of commercially available thrombin generation assays

Research and Practice in Thrombosis and Haemostasis, 2017
Essentials Overview of the three commercial thrombin generation methods. Description of the sample preparation, data management, and analysis. Description of the similarities and differences in regards to substrates results.
J. Kintigh, P. Monagle, V. Ignjatovic
semanticscholar   +1 more source

Thrombin generation assay parameters.

, 2018
Thrombin generation assay parameters.
Nicola Pozzi (2866730), Piotr Zalicki (5587076), Kevin M. Short (5587079), David C. Williams (2680522), Matthew Rienzo (1997911), M. Angels Estiarte (2354884), Lev Igoudin (5587073), Enrico Di Cera (2495530), Mohanram Sivaraja (2004994), Kenneth Lin (1547371), Timothy P. Shiau (2516746), Anirban Datta (225408), Stephanie S. Chang (5466101), Daniel M. Clemens (5587070), David B. Kita (5587082)   +14 more
core   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source