Results 61 to 70 of about 2,633,554 (103)

Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIba.

, 2015
BACKGROUND: Platelets are essential for maintaining haemostasis and play a key role in the pathogenesis of cardiovascular disease. Upon ligation of platelet receptors through subendothelial matrix proteins, intracellular reactive oxygen species (ROS) are
E. Gardiner (23305693), Pat Metharom (23340427), J. Hamilton (1599490), J. Arthur (23305696), N. Carrim (23322985), R. Andrews (2731252), Michael Berndt (23285713), N. Moran (23401801)   +7 more
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Thrombin generation assays (TGAs)

, 2017
In recent years, there has been a revival of interest in a time-honored tool of the clotting trade: the thrombin generation curve or thrombin generation (TG) assay (TGA) as we now call it.
Erik Berntorp, Gian Luca Salvagno, Berntorp, Erik, Salvagno, Gian Luca   +3 more
core   +1 more source

Monitoring platelet dependent thrombin generation in mice

, 2010
Calibrated automated thrombin generation assay was adapted to measure thrombin generation in platelet rich plasma from mice. Vena cava phlebotomy appeared the best technique for blood sampling.
Hemker, H. Coenraad, Henri M.H. Spronk, Yesim Dargaud, Dargaud, Yesim, Ten Cate, Hugo, Peter Leenders, Hugo Ten Cate, Leenders, Peter, H. Coenraad Hemker, Spronk, Henri M. H.   +9 more
core   +1 more source

Elevated tissue factor pathway inhibitor delays thrombin generation in COVID-19 but is not associated with clinical outcomes

Blood Vessels, Thrombosis & Hemostasis
: Plasma levels of tissue factor pathway inhibitor (TFPI) are elevated in many patients with COVID-19 but the role of TFPI in COVID-19 coagulopathy remains elusive.
Alicia S. Eustes, Meena Kumari Palani Kumar, Julie A. Peterson, Alan E. Mast, Steven R. Lentz, Sanjana Dayal   +5 more
doaj   +1 more source

USE OF THROMBIN GENERATION ASSAY FOR THE EVALUATION OF COAGULATION AND ANTICOAGULANT ACTIVITY OF HEMOSTASIS SYSTEM IN PATIENTS WITH ABDOMINAL SEPSIS

Вестник хирургии имени И.И. Грекова, 2018
Generally recognized factor, which complicates the course of sepsis, is the development of hypercoagulation syndrome. The increase of thrombin coagulation indicates on the elevation of risk of thrombus formation in microcirculation vessels, which could ...
Kh. A. Gamzatov, D. V. Gurzhy, S. M. Lazarev, Yu. A. Namestnikov, A. A. Lerner, L. P. Papayan, O. G. Golovina, E. A. Khait, O. A. Smirnova, O. Yu. Matvienko   +9 more
doaj   +1 more source

Rhodostomin Inhibits Thrombin-Enhanced Adhesion of Ros 17/2.8 Cells through the Blockade of αvβ3 Integrin

, 2008
Osteosarcoma is a very malignant bone tumor which has a high metastatic potential and usually lead to poor prognosis. The adhesion of tumor cells to the endothelium or extracellular matrix (ECM) is an essential step in the metastatic cascade.
YANG, RONG-SEN;TANG, CHIH-HSIN;YEH, CHIA-HSIN;HUANG, TUR-FU, 楊榮森;湯智昕;葉嘉新;黃德富   +1 more
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Thrombin generation after cariopulmonary bypass

, 2010
Thrombin ist das Schlüsselenzym der Gerinnung. Prothrombotische Komplikationen wie Schlaganfälle und Herzinfarkte, sind nach Herzoperationen häufig.
Englhard, Anna Sophie
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Analysis of thrombin generation in plasma [PDF]

, 1994
Thrombin is the central enzyme of haemostasis. Information on the production and inhibition of thrombin in plasma is important for evaluating the state of the coagulation system.
Hemker, H. Coenraad, Willems, George, Kessels, Han   +2 more
core   +2 more sources

Thrombin generation in ischemic stroke

Stroke is a leading cause of adult disability and mortality worldwide. Thrombosis is central to cerebral vascular occlusion that causes stroke therefore targeting coagulation remains at the centre of stroke treatment and prevention. Thrombin is a central
Falcione, Sarina R.
core   +1 more source

The effect of combined oral contraceptives on thrombin generation assessed on ST Genesia– a paired clinical study

Thrombosis Journal
Background Treatment with combined oral contraceptives (COC) is associated with an increased risk of venous thromboembolism. Several changes of coagulant and anticoagulant factors induced by ethinyloestradiol during treatment with COC, have been ...
Jesper Strandberg, Inger Lise Gade, Jette Nybo, Janus Nikolaj Laust Thomsen, Søren Risom Kristensen   +4 more
doaj   +1 more source