Results 51 to 60 of about 97,937 (350)
Apixaban Enhances Endogenous Fibrinolysis in Patients with Atrial Fibrillation [PDF]
, 2019 © The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.AIMS: Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which ...
Arachchillage, Deepa RJ +7 more
core +3 more sources
Thrombin generation in vascular tissue [PDF]
Journal of Thrombosis and Haemostasis, 2006 Classically, it is thought that the vast majority of thrombin is generated on the surface of platelets, however, thrombotic events occur in patients despite treatment with potent antiplatelet agents.In freshly harvested left internal mammary artery (IMA) sections, addition of CaCl2 and platelet-poor plasma (PPP) were sufficient to stimulate a profound ...
A, Pathak +6 more
openaire +2 more sources
Thrombosis Journal, 2022 Background Supplementation with antithrombin (AT) concentrates is now common in the treatment of congenital and acquired AT deficiency. However, there is no established consensus on the target and timing of supplementation.
Takumi Tsuchida +3 more
doaj +1 more source
Effects of platelets activated by different agonists on fibrin formation and thrombin generation
Platelets, 2023 Activated platelets possess procoagulant activity expressing on their surface phosphatidylserine (PS), a substrate for assembling coagulation complexes. We examined the effects of platelets activated by different agonists on fibrin formation and thrombin
Ivan A. Muravlev +4 more
doaj +1 more source
Modelling of thrombin generation under flow in realistic left anterior descending geometries [PDF]
, 2017 Currently there are no available methods for prediction of thrombotic complications in Coronary Artery disease. Additionally, blood coagulation tests are mainly performed in a steady system while coagulation in vivo occurs under flow conditions.
Gavaises, M. +2 more
core +2 more sources
Research and Practice in Thrombosis and Haemostasis, 2020 Combined oral contraceptives and factor V Leiden mutation are multiplicative risk factors for venous thromboembolism. However, it remains unknown whether this multiplicative effect is reflected in thrombin generation assays.
Maxime G. Zermatten +3 more
doaj +1 more source
Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]
, 2018 © The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast +66 more
core +2 more sources
Thrombin-generating capacity in patients with von Willebrand’s disease
Haematologica, 2007 Background and Objectives on Willebrand’s disease (VWD) is the most common hereditary bleeding disorder. Its severity can be classified on the basis of von Willebrand factor (VWF) and factor VIII (FVIII) plasma levels and according to the clinical ...
Lucia Rugeri +7 more
doaj +1 more source
Global Thrombosis Test - a possible monitoring system for the effects and safety of dabigatran [PDF]
, 2015 © Otsui et al. 2015BACKGROUND: Dabigatran is an alternative to warfarin (WF) for the thromboprophylaxis of stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran over WF is that monitoring is not required; however, a
Gorog, Diana A +8 more
core +2 more sources
Research and Practice in Thrombosis and Haemostasis, 2021 Introduction Plasma thrombin generation kinetics as measured by the calibrated automated thrombogram (CAT) assay is a predictor of symptomatic venous thromboembolism after trauma.
Michael J. Ferrara +11 more
doaj +1 more source