Results 31 to 40 of about 2,633,554 (103)

Follow-up of thrombin generation after prostate cancer surgery: global test for increased hypercoagulability. [PDF]

PLoS ONE, 2012
Recent studies provided evidence that evaluation of thrombin generation identifies patients at thrombotic risk. Thrombin generation has a central role in hemorrhage control and vascular occlusion and its measurement provides new metrics of these ...
Matyas Benyo, Tibor Flasko, Zsuzsanna Molnar, Adrienne Kerenyi, Zoltan Batta, Tamas Jozsa, Jolan Harsfalvi   +6 more
doaj   +1 more source

Thrombin generation capacity is enhanced by low antithrombin activity and depends on the activity of the related coagulation factors

Thrombosis Journal, 2022
Background Supplementation with antithrombin (AT) concentrates is now common in the treatment of congenital and acquired AT deficiency. However, there is no established consensus on the target and timing of supplementation.
Takumi Tsuchida, Mineji Hayakawa, Shota Kawahara, Osamu Kumano   +3 more
doaj   +1 more source

Effects of platelets activated by different agonists on fibrin formation and thrombin generation

Platelets, 2023
Activated platelets possess procoagulant activity expressing on their surface phosphatidylserine (PS), a substrate for assembling coagulation complexes. We examined the effects of platelets activated by different agonists on fibrin formation and thrombin
Ivan A. Muravlev, Anatoly B. Dobrovolsky, Olga A. Antonova, Svetlana G. Khaspekova, Alexey V. Mazurov   +4 more
doaj   +1 more source

thrombin-Piperidine PDB file

, 2020
PDB file used for thrombin-piperidine ...
Stefan Doerr (748688)
core   +1 more source

Thrombin generation in a woman with heterozygous factor V Leiden and combined oral contraceptives: A case report

Research and Practice in Thrombosis and Haemostasis, 2020
Combined oral contraceptives and factor V Leiden mutation are multiplicative risk factors for venous thromboembolism. However, it remains unknown whether this multiplicative effect is reflected in thrombin generation assays.
Maxime G. Zermatten, Debora Bertaggia Calderara, Alessandro Aliotta, Lorenzo Alberio   +3 more
doaj   +1 more source

Thrombin generation in obstetric haemorrhage [PDF]

The haemostatic system undergoes significant changes during pregnancy, particularly at term, leading to alterations in coagulation factors and anticoagulants.
Freyer Martins Pereira, Julia
core   +6 more sources

The Phosphatase Inhibitor Calyculin-A Impairs Clot Retraction, Platelet Activation, and Thrombin Generation [PDF]

, 2017
The aim of this study was to investigate the effect of the serine/threonine protein phosphatase inhibitor, calyculin-A (CLA), on clot formation and on the procoagulant activity of human platelets. Platelet-rich plasma (PRP) samples were preincubated with
Clemetson, Kenneth John, László Csernoch, Ferenc Erdődi, Kenneth J. Clemetson, Erdődi, Ferenc, Kappelmayer, János, Oláh, Tamás, Tamás Oláh, Beke Debreceni, Ildikó, Renáta Hudák, János Kappelmayer, Csernoch, László, János Vincze, Hudák, Renáta, Vincze, János, Ildikó Beke Debreceni   +15 more
core   +2 more sources

Thrombin generation tests

, 2011
The recent development of semi-automated methods has revived interest in the thrombin generation test, a global assay that measures the overall tendency of a plasma sample to form thrombin after initiation of coagulation.
Castoldi, Elisabetta, Elisabetta Castoldi, Jan Rosing, Rosing, Jan   +3 more
core   +1 more source

Cystamine inhibits thrombin generation.

, 2015
Plasma thrombin generation was triggered by re-calcification and addition of tissue factor and phospholipids, in the presence of cystamine. Thrombin generation was monitored by calibrated automated thrombography.
Maria M. Aleman (730511), Christa I. Devette (730513), Lori A. Holle (730512), Dougald M. Monroe (730514), Katherine G. Stember (647428), Alisa S. Wolberg (695929)   +5 more
core   +1 more source

Thrombin Generation in Zebrafish Blood. [PDF]

, 2016
To better understand hypercoagulability as an underlying cause for thrombosis, the leading cause of death in the Western world, new assays to study ex vivo coagulation are essential.
Schurgers, Evelien, Moorlag, Martijn, Coenraad Hemker, Hemker, Hendric, Theo Lindhout, de Laat, Bas, Lindhout, Theo, Evelien Schurgers, Kelchtermans, Hilde, Bas de Laat, Martijn Moorlag, Hilde Kelchtermans   +11 more
core   +1 more source