Results 41 to 50 of about 2,633,554 (103)

Thrombin generation correlates with disease duration in multiple sclerosis (MS): Novel insights into the MS-associated prothrombotic state

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2017
Background Thrombin is well recognised for its role in the coagulation cascade but it also plays a role in inflammation, with enhanced thrombin generation observed in several inflammatory disorders.
Martin EM Parsons, Karen O’Connell, Seamus Allen, Karl Egan, Paulina B Szklanna, Christopher McGuigan, Fionnuala Ní Áinle, Patricia B Maguire   +7 more
doaj   +1 more source

Semi-automated thrombin dynamics applying the ST Genesia thrombin generation assay

Frontiers in Cardiovascular Medicine, 2022
BackgroundThe haemostatic balance is an equilibrium of pro- and anticoagulant factors that work synergistically to prevent bleeding and thrombosis.
Audrey Carlo, Qiuting Yan, Qiuting Yan, Hugo Ten Cate, Romy De Laat-Kremers, Romy De Laat-Kremers, Bas De Laat, Bas De Laat, Marisa Ninivaggi   +8 more
doaj   +1 more source

Thrombin generation - a potentially useful biomarker of thrombotic risk in Philadelphia-negative myeloproliferative neoplasms

Biomedical Papers, 2017
The diagnosis of essential thrombocythemia and polycythemia vera is often made during a thrombotic event which can be serious. Philadelphia-negative chronic myeloproliferative neoplasia patients have an increased thrombotic risk.
Romeo-Gabriel Mihaila
doaj   +1 more source

Inhibition of thrombin generation 12 hours after intake of direct oral anticoagulants

Research and Practice in Thrombosis and Haemostasis, 2020
Background The residual antithrombotic activity 12 hours after intake of direct oral anticoagulants (DOACs) is of clinical relevance in the setting of bleeding or urgent surgery.
Michael Metze, Christian Pfrepper, Tristan Klöter, Stephan Stöbe, Roland Siegemund, Thomas Siegemund, Elvira Edel, Ulrich Laufs, Sirak Petros   +8 more
doaj   +1 more source

Enhanced plasma thrombin generation and MP-induced thrombin generation in patients with high CAC.

, 2016
(A) In patients with high CAC compared to patients with low CAC TATc level as a marker of thrombin generation in plasma were higher. (C) TATc level correlated with CAC Score.
Ralf Westenfeld (309533), Gülsüm Erkilet (2580877), Patric Kröpil (581138), Tobias Zeus (655476), Patrick Horn (47116), Malte Kelm (45981), Christian Heiss (446842), Leon Schurgers (560257), Verena Veulemans (309535)   +8 more
core   +1 more source

Overview of thrombin generation parameters.

, 2022
Overview of thrombin generation parameters.
Astrid van Hylckama Vlieg (335532), Carolina E. Touw (12152623), Ype de Jong (602387)   +2 more
core   +1 more source

Thrombin generation assay parameters.

, 2018
Thrombin generation assay parameters.
Nicola Pozzi (2866730), Piotr Zalicki (5587076), Kevin M. Short (5587079), David C. Williams (2680522), Matthew Rienzo (1997911), M. Angels Estiarte (2354884), Lev Igoudin (5587073), Enrico Di Cera (2495530), Mohanram Sivaraja (2004994), Kenneth Lin (1547371), Timothy P. Shiau (2516746), Anirban Datta (225408), Stephanie S. Chang (5466101), Daniel M. Clemens (5587070), David B. Kita (5587082)   +14 more
core   +1 more source

Recurrent venous thromboembolism: association with thrombin generation and d-dimer

Research and Practice in Thrombosis and Haemostasis
Background: In patients with a first event of venous thromboembolism (VTE) clinicians must decide when to stop anticoagulation, evaluating the risk of recurrent thrombosis.
Eugenia Biguzzi, Kristien Winckers, Tilman M. Hackeng, Frits R. Rosendaal, Astrid van Hylckama Vlieg   +4 more
doaj   +1 more source

Thrombin Generation in Chinese Pregnant Women and the Effect of Insulin Use on Thrombin Generation in Patients with GDM

Clinical and Applied Thrombosis/Hemostasis, 2019
Pregnancy is a hypercoagulable state associated with an increased risk of venous thrombosis. Calibrated automated thrombogram (CAT) is a test to monitor the thrombin generation (TG), a laboratory marker of thrombosis risk, and increases during normal ...
Feng Dong MM, Longhao Wang MM, Chengbin Wang MD   +2 more
doaj   +1 more source

Thrombin generation on coated discs.

, 2015
Thrombin generation for discs coated with either ApoA-I-, ApoB-, Isotype- or no antibody (empty discs), compared to thrombin generation in absence of a disc (negative control). (n = 4).
Leo H. Koole (538507), Aart C. Strang (714400), Allard C. van der Wal (33616), Paul P. Tak (23064), Erik S. G. Stroes (213339), Joris I. Rotmans (530517), Robbert J. de Winter (372354), Carlie J. M. de Vries (631854), Menno L. W. Knetsch (714401), Radjesh J. Bisoendial (714402)   +9 more
core   +1 more source