Results 61 to 70 of about 15,175 (215)

Distinct clinical characteristics of myeloproliferative neoplasms with calreticulin mutations

Haematologica, 2014
Somatic insertions/deletions in the calreticulin gene have recently been discovered to be causative alterations in myeloproliferative neoplasms. A combination of qualitative and quantitative allele-specific polymerase chain reaction, fragment-sizing ...
Hajnalka Andrikovics, Tunde Krahling, Katalin Balassa, Gabriella Halm, Andras Bors, Magdalena Koszarska, Arpad Batai, Janos Dolgos, Judit Csomor, Miklos Egyed, Andrea Sipos, Peter Remenyi, Attila Tordai, Tamas Masszi   +13 more
doaj   +1 more source

CARDIOVASCULAR RISK IN ESSENTIAL THROMBOCYTHEMIA AND POLYCYTHEMIA VERA: THROMBOTIC RISK AND SURVIVAL

Mediterranean Journal of Hematology and Infectious Diseases, 2020
Thromboembolic and bleeding events pose a severe risk for patients with Polycythemia Vera (PV) and Essential Thrombocythemia (ET). Many factors can contribute to determine the thrombotic event, including the interaction between platelets, leukocytes and ...
Vincenzo Accurso, Marco Santoro, Salvatrice Mancuso, Angelo Davide Contrino, Paolo Casimio, Mariano Sardo, Simona Raso, Florinda Di Piazza, Alessandro Perez, Marco Bono, Antonio Russo, Sergio Siragusa   +11 more
doaj   +1 more source

A case of essential thrombocythemia and ankylosing spondylitis treated with a combination of anagrelide, disease-modifying antirheumatic drugs, and etanercept [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2016
Introduction. A high platelet count, or thrombocytosis, is either a reactive process or a result of a myeloproliferative disorder. Ankylosing spondylitis is a chronic inflammatory rheumatic disease affecting the spine and sometimes peripheral ...
Zeremski Vanja, Savić Aleksandar, Ilić Tatjana, Milošević Ivana, Maksimović Marina, Vučković Biljana   +5 more
doaj   +1 more source

The Underestimated Role of Environmental Factors in the Prevention of Invasive Fungal Disease: Experience From a European Childhood Cancer Centre

Mycoses, Volume 69, Issue 7, July 2026.
ABSTRACT Background Immunocompromised children with hematologic malignancies or undergoing allogeneic haematopoietic stem cell transplantation (HSCT) are at high risk for invasive fungal diseases (IFDs). Reported incidence varies considerably due to heterogeneous diagnostic criteria, antifungal strategies and environmental conditions.
Stefano Malvestiti, Felicia Andresen, Markus Hufnagel, Carsten Speckmann, Brigitte Strahm, Tobias Feuchtinger, Alexander Puzik   +6 more
wiley   +1 more source

The human myeloproliferative disorders: molecular pathogenesis and clonal heterogeneity

, 2010
The classical myeloproliferative disorders (MPD), comprising essential thrombocythaemia (ET), polycythaemia vera (PV) and idiopathic myelofibrosis (IMF), are clonal premalignant haematopoietic neoplasms associated with activating mutations in signalling ...

core   +1 more source

Positive and Negative Cardiovascular Effects of JAK Inhibitors in Inflammation

ACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Chronic inflammation, characteristic of many autoimmune diseases, such as rheumatoid arthritis (RA), or myeloproliferative neoplasms (MPNs), is an independent driver of accelerated cardiovascular (CV) risk, primarily through proinflammatory cytokines that induce atherosclerosis and endothelial dysfunction.
Aliki Zavoriti, Pierre Miossec
wiley   +1 more source

Pyoderma Gangrenosum in a Patient with Essential Thrombocythemia

, 2000
Background: Pyoderma gangrenosum is an uncommon ulcerative condition associated with inflammatory bowel disease, arthritis, and hematologic disease. We report a patient with essential thrombocythemia and pyoderma gangrenosum. Objective: This article is a
Kim W. King, Alexander Murray
core   +1 more source

Systemic mastocytosis and essential thrombocythemia: Case report and literature overview [PDF]

, 2019
Case report of a patient with essential thrombocythemia and mastocytosis and overview of the ...
Sandro Giannini, Giannini S., Fabris, F., Cosi, E., Pizzi, M., Maria Luigia Randi, Mauro Cancian, Marco Pizzi, Randi M. L., Irene Bertozzi, Pizzi M., Cosi E., Cancian M., Cancian, M., Giannini, S., Randi, M. L., Bertozzi, I., Fabris F., Elisabetta Cosi, Bertozzi I., Fabrizio Fabris   +20 more
core   +1 more source

Essential thrombocythemia and acute myocardial infarction treated with rescue coronary angioplasty

Arquivos Brasileiros de Cardiologia, 1999
A 48-year-old man with essential thrombocythemia suffered an extensive anterior acute myocardial infarction; this is a rare association. A pharmacological thrombolysis was performed, without success.
Antonio Esteves Fº, Francisco de Assis Costa, Antonio Augusto Guimarães Lima, Luiz Junya Kajita, Eulógio Emílio Martinez Fº   +4 more
doaj   +1 more source

Cytokine receptor and JAK/STAT pathway mutations in acute myeloid leukemia: Prevalence and clinical impact

Cancer, Volume 132, Issue 11, 1 June 2026.
Abstract Background Mutations in cytokine receptor and JAK/STAT; Cy‐JAK/STAT) signaling genes drive myeloproliferative neoplasms (MPNs) but remain incompletely characterized in acute myeloid leukemia (AML). The authors evaluated the prevalence, clinical presentation, and prognostic significance of Cy‐JAK/STAT pathway mutations in patients with AML and ...
Moath Albliwi, Daniel P. Nurse, Emily C. Zabor, John Hanna, Jessica El‐Asmar, Ameed Bawwab, Hasan Abuamsha, Yomna Abu‐Farsakh, Heya Batah, Asad Rauf, Joy Nakitandwe, David S. Bosler, Prerana Bangalore Parthasarathy, Tyler Alban, Akriti G. Jain, John C. Molina, Sophia Balderman, Abhay Singh, Aaron T. Gerds, Sudipto Mukherjee, Anjali S. Advani, Hetty E. Carraway, Moaath K. Mustafa Ali   +22 more
wiley   +1 more source