Results 31 to 40 of about 67,161 (291)

Association Between the Use of Pre- and Post-thrombolysis Anticoagulation With All-Cause Mortality and Major Bleeding in Patients With Pulmonary Embolism

Frontiers in Cardiovascular Medicine, 2022
ObjectiveTo explore the comparative clinical efficacy and safety outcomes of anticoagulation before (pre-) or following (post-) thrombolytic therapy in systemic thrombolytic therapy for pulmonary embolism (PE).MethodsPubMed, the Cochrane Library, EMBASE,
Jiang-Shan Tan, Ningning Liu, Ningning Liu, Song Hu, Yan Wu, Xin Gao, Ting-Ting Guo, Xin-Xin Yan, Fu-Hua Peng, Lu Hua   +9 more
doaj   +1 more source

Tissue plasminogen activator dose and pulmonary artery pressure reduction in catheter directed thrombolysis of submassive pulmonary embolism. [PDF]

, 2019
PURPOSE:The purpose of this study is to assess the incremental effect of tissue plasminogen activator (t-PA) dose on pulmonary artery pressure (PAP) and bleeding during catheter directed thrombolysis (CDT) of submassive pulmonary embolism (PE). MATERIALS
Gaba, Ron C, Liu, Li, Lokken, R Peter, Patel, Darshan C   +3 more
core   +2 more sources

Is primary angioplasty cost effective in the UK? Results of a comprehensive decision analysis [PDF]

, 2007
Objective: To assess the cost effectiveness of primary angioplasty, compared with medical management with thrombolytic drugs, to achieve reperfusion after acute myocardial infarction ( AMI) from the perspective of the UK NHS.
Abrams, Keith, Asseburg, Christian, de Belder, Mark, Fenwick, Elisabeth, Palmer, Stephen, Sculpher, Mark, Vergel, Yolanda Bravo   +6 more
core   +2 more sources

Transcranial Histotripsy Clot and Tissue Ablation for Intracerebral Hemorrhage Evacuation and Other Brain Applications

, 2023
STROKE: Vascular and Interventional Neurology, EarlyView.
Jonathan Sukovich, Zhen Xu, Aditya S. Pandey   +2 more
wiley   +1 more source

Total Thiols and MDA Levels in Patients with Acute Myocardial Infarction Before and After Reperfusion Therapy [PDF]

, 2010
Background: Reactive oxygen species have been implicated in the pathogenesis of ischemic and reperfusion injury. In the current work we have measured malondialdehyde (MDA), total thiols, total CK, CK-MB and AST in ECG proven acute myocardial infarction ...
Babu, Suresh, Mungli, Prakash, Shetty, Jeevan K   +2 more
core   +1 more source

rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]

, 2014
BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy, Eastwood, Jo-Ann, Gylys, Karen, Meyer, Dawn M, Zivin, Justin A   +4 more
core   +3 more sources

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Systemic Thrombolytic Therapy Alone and in Combination with Mechanical Revascularization in Acute Ischemic Stroke in Two Children

Case Reports in Neurology, 2011
Thrombolytic therapy is not recommended for acute ischemic stroke (AIS) in patients under the age of 18 and published experience is limited. In this case report, we describe two children treated with systemic thrombolytic therapy.
B. Modrau, L. Sørensen, N.J. Bartholdy, P. von Weitzel-Mudersbach, G. Andersen, P.V. Rasmussen   +5 more
doaj   +1 more source

In silico assessment of histotripsy-induced changes in catheter-directed thrombolytic delivery

Frontiers in Physiology, 2023
Introduction: For venous thrombosis patients, catheter-directed thrombolytic therapy is the standard-of-care to recanalize the occluded vessel. Limitations with thrombolytic drugs make the development of adjuvant treatments an active area of research ...
Kenneth B. Bader, Katia Flores Basterrechea, Samuel A. Hendley   +2 more
doaj   +1 more source

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani, Dylan N. Wolman, Tyler M. Bielinski, Nitin Goyal, Jeremy B. Rhoten, Mahesh V. Jayaraman, Christian T. Sidebottom, Bradley A. Gross, Alhamza R. Al‐Bayati, Mohamed F. Doheim, Matthew K. Tobin, Anoop Chinthala, Avi Gajjar, Justin Mascitelli, Matthew R. Webb, Jan‐Karl Burkhardt, Kyle W. Scott, Visish Srinivasan, Daniel Tonetti, Manisha Koneru, David J. Altschul, Dhrumhil Vaishnav, Sumeet Multani, Thana Theofanis, William J. Ares, Je Yeong Sone, Ramin Zand, Sasan Bahrami, Jiang Li, Gary Defilipp, Dale Strong, Radmehr Torabi, Krisztina Moldovan, Kelsey E. Kline, Clemens M. Schirmer, Raul G. Nogueira, Alexandra R. Paul, Bradley N. Bohnstedt, Philipp Hendrix   +38 more
wiley   +1 more source