Evidence supporting idarucizumab for the reversal of dabigatran. [PDF]
Idarucizumab is a monoclonal antibody fragment specifically targeted to dabigatran. It has demonstrated prompt and durable reversal of the anticoagulant effects of dabigatran in animal studies and phase 1 studies of young, elderly, and renally impaired ...
Pollack, Charles V.
core +2 more sources
Laboratory Monitoring of Heparin Therapy: Partial Thromboplastin Time or Anti-Xa Assay?
The activated partial thromboplastin time (PTT) is the principal method by which laboratories monitor unfractionated heparin therapy. A review of the experimental basis for heparin monitoring by the PTT reveals significant shortcomings of the assay.
C. M. Lehman, E. L. Frank
semanticscholar +1 more source
A case of amebic colitis: A potentially fatal mimicker of inflammatory bowel disease
ABSTRACT Amebiasis, caused by Entamoeba histolytica, can present diagnostic challenges due to its diverse clinical manifestations and potential for misdiagnosis, particularly in regions with low incidence rates. We report a case of a 9‐year‐old girl initially diagnosed with inflammatory bowel disease but later confirmed to have amebic colitis.
Fadhel Al Ateeqi+2 more
wiley +1 more source
ABSTRACT Hypercoagulability contributes to atherosclerosis (AS) progression in individuals suffering from rheumatoid arthritis (RA), and thromboelastography (TEG) is a valuable diagnostic tool. This hospital‐based cross‐sectional study assessed the clinical efficacy of TEG parameters in detecting hypercoagulability and subclinical AS by purposively ...
Qing‐Lin Zhang+6 more
wiley +1 more source
Fibrin D-dimer, markers of coagulation activation and the risk of major ischaemic heart disease in the Caerphilly Study [PDF]
We have previously reported that plasma fibrin D-dimer (a marker of turnover of cross-linked Fibrin) showed a strong and independent association with incident ischaemic heart disease (IHD) in the Caerphilly Study cohort of 1,998 men a-ed 49-65.
Lowe, G.D.O.+4 more
core +1 more source
Microbiota diversity and differences in the respiratory tract of children with pneumonia
Differences in microbial communities in the upper and lower respiratory tract in patients with pneumonia were investigated in this study by sequencing the 16S rRNA genes in pharyngeal swabs and alveolar lavage fluid. Forty‐three subjects were enrolled in the study, and one upper and one lower respiratory tract sample were collected from each subject ...
Dandan Ge+4 more
wiley +1 more source
Antiphosphatidylserine antibody as a cause of multiple dural venous sinus thromboses and ST-elevation myocardial infarction [PDF]
Objective: Rare disease Background: Antiphospholipid syndrome (APS) is an autoimmune disease characterized by antibodies directed against phos-pholipids on plasma membranes. Through unclear mechanisms, APS confers hypercoagulability.
Marquardt, Caillin W.+2 more
core +1 more source
Beating heart coronary surgery and renal function: a prospective randomised study (Presented at 18th Spring Meeting of the Association of Cardiothoracic Anaesthetists: Selected abstracts, Cambridge, UK. 22 June 2001) [PDF]
Introduction Cardiopulmonary bypass (CPB) is widely regarded as an important contributor to renal failure, a well recognised complication, following coronary artery surgery (CABG).
A Tang+6 more
core +2 more sources
Hematological Changes Post-Hemo and Peritoneal Dialysis Among Renal Failure Patients in Sudan
The objective of the study was to assess the changes that occur in various hematological parameters that may occur in renal failure patients after hemo and peritoneal dialysis sessions.
Mohamed Ali Mohamed+4 more
doaj
Acute Lung Lesion Caused by Microvascular Thrombosis
Objective. To assess a role of pulmonary microvascular thrombosis in the development of acute lung lesion.Material and methods. Experiments were carried out on 60 albino non-inbred male rats.
A. M. Golubev+4 more
doaj +1 more source