Results 81 to 90 of about 74,738 (274)

The Relationship Between Blood Lipids, Coagulation Indexes, Blood Homocysteine and Sudden Deafness: A Retrospective Study and Mendelian Randomization Analysis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Certain blood components, including blood lipids, coagulation parameters, and homocysteine, have been suggested to correlate with the incidence and prognosis of sudden sensorineural hearing loss (SSNHL). However, the nature of these associations remains controversial.
Feng‐Xin Yang, Yu‐Wan Song, Yan Wang, Kun Zhao, Hu‐Hui‐Fen He, Jing‐Jing Qiu, Da‐Wei Liu, Bo Li, Yan Sun   +8 more
wiley   +1 more source

Evolutionary Mechanisms of Coagulation Factors in Cetaceans During Aquatic Adaptation

Integrative Zoology, EarlyView.
Compared with Bos taurus, T. truncatus showed shorter prothrombin time and thrombin time but prolonged activated partial thromboplastin time, indicating pathway‐specific remodeling of coagulation. Evolutionary analyses identified 18 positively selected genes and accelerated F11 evolution, while functional assays revealed increased coagulation factor ...
Wenjun Lv, Wanfei Deng, Fei Deng, Shixia Xu, Wenhua Ren   +4 more
wiley   +1 more source

Relationship between lipid metabolism, coagulation and other blood indices and etiology and staging of non-traumatic femoral head necrosis: a multivariate logistic regression-based analysis

Journal of Orthopaedic Surgery and Research
Background To analyze the relationship between lipid metabolism, coagulation function, and bone metabolism and the contributing factor and staging of non-traumatic femoral head necrosis, and to further investigate the factors influencing the blood ...
Ximing Yu, Shilu Dou, Liaodong Lu, Meng Wang, Zhongfeng Li, Dongwei Wang   +5 more
doaj   +1 more source

Prothrombine and activated partial thromboplastin time are prolonged in hepatic cirrhosis

Universa Medicina, 2016
Background Chronic hepatitis and hepatic cirrhosis are chronic liver diseases that cause disorders of liver function, such as the formation of platelets and coagulation factors (prothrombin time/PT and activated partial thromboplastin time/APTT ...
Edward Kurnia Setiawan Limijadi, Lisyani Budi Suromo, Imam Budiwiyono   +2 more
doaj   +1 more source

Some Aspects of Kinetics of the First Stages of Blood Thromboplastin Formation

, 1959
SummaryThe first stages of blood thromboplastin generation were investigated. Plasma Thromboplastin Antecedent, Prephase Accelerator, and Hageman factor are involved in the reactions taking place during the lag period.
U Fisch, F Duckert
core   +1 more source

A Rare Case of Acquired Haemophilia A Following Sigmoid Adenocarcinoma: Case Report and Literature Review

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Acquired haemophilia A (AHA) is a rare complication of malignancy. We report a case of AHA secondary to colorectal cancer which presented as post‐operative bleeding, progressive activated partial thromboplastin time prolongation, precipitous factor VIII (FVIII) decline and inhibitor development.
Benjamin Reardon, Harini Haran, Jennifer Curnow   +2 more
wiley   +1 more source

Abnormal activated partial thromboplastin time and malignancy

, 2011
Malignancy often results in clotting abnormalities. The aetiology of haemostasis problems in cancer is complex, and is still not completely understood. We describe a case of a patient with malignant mesothelioma, who was found to have elevated activated
H Hambley, M Delicata
core   +1 more source

Initial V‐A ECMO Flow‐Index and Its Association With Inflammation, Organ Failure, and Outcomes

Artificial Organs, EarlyView.
Higher initial V‐A ECMO flow‐index was associated with greater shock severity and independently associated with multi‐organ failure. Early hemolysis may partly contribute to this association, particularly in eCPR patients, whereas no significant indirect effect through IL‐6 was observed.
Kostiantyn Kozakov, Zdenek Provaznik, Alois Philipp, Maik Foltan, Christian Schach, Sergey Vasin, Andreas Keyser, Leopold Rupprecht, Christof Schmid, Simon Schopka   +9 more
wiley   +1 more source

Influence of Thromboplastin on the Development of Transplantable Tumors

, 1966
Thromboplastin administration, simultaneous to the inoculation of neoplastic cells (Ehrlich adenocarcinoma in the mouse and reticulosarcoma IRE in the rat), caused a significant shortening of the latent period for tumor development and of the survival ...
Donato Fumarola, Pietro De Rinaldis, Paolo Restuccia   +2 more
core   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source