Results 41 to 50 of about 3,536 (218)

Role of plasma exchange in postpartum microangiopathies: An experience from a tertiary care center

open access: yesAsian Journal of Transfusion Science, 2019
BACKGROUND: Postpartum microangiopathies are rare but are associated with high maternal and fetal mortality requiring early diagnosis and prompt treatment to improve the outcome.
Rekha Hans   +6 more
doaj   +1 more source

Syndromes of Thrombotic Microangiopathy [PDF]

open access: yesNew England Journal of Medicine, 2014
This review article covers the diverse pathophysiological pathways that can lead to microangiopathic hemolytic anemia and a procoagulant state with or without damage to the kidneys and other organs.
Koemhoff, Martin   +2 more
openaire   +7 more sources

Pathogenesis of Thrombotic Microangiopathies [PDF]

open access: yesAnnual Review of Pathology: Mechanisms of Disease, 2007
Profound thrombocytopenia and microangiopathic hemolytic anemia characterize thrombotic microangiopathy, which includes two major disorders: thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). TTP has at least three types: congenital or familial, idiopathic, and nonidiopathic.
X Long, Zheng, J Evan, Sadler
openaire   +2 more sources

Thrombotic Microangiopathy and the Kidney [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2017
Thrombotic microangiopathy can manifest in a diverse range of diseases and is characterized by thrombocytopenia, microangiopathic hemolytic anemia, and organ injury, including AKI. It can be associated with significant morbidity and mortality, but a systematic approach to investigation and prompt initiation of supportive management and, in some cases ...
Brocklebank V, Wood KM, Kavanagh D
openaire   +3 more sources

Difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unit

open access: yesВестник анестезиологии и реаниматологии, 2019
Atypical hemolytic uremic syndrome (aHUS) is an orphan disease, representing one of thrombotic microangiopathies, the natural course of which leads to an unfavorable outcome often accompanied by multiple organ failure in the onset of the disease ...
N. L. Kozlovskаya   +2 more
doaj   +1 more source

Histopathological features of thrombotic microangiopathies in renal biopsies [PDF]

open access: yesJournal of Nephropathology, 2019
Background: Thrombotic microangiopathy (TMA) is a morphologic lesion characterized by thrombi occluding microvasculature related to endothelial injury. Objectives: This study aimed to assess the association between histopathological findings and etiology
Miguel Ernandes Neto   +5 more
doaj   +1 more source

Utility of Different Scoring Systems for the Diagnosis of Thrombotic Microangiopathies

open access: yes, 2023
Objective: To investigate the appropriateness of Bentley and plasmic scores and ADAMTS-13 activity to distinguish between primary thrombotic microangiopathies (TMA) syndromes and other thrombotic microangiopathies, as well as primary thrombotic ...
Yilmaz, Seda   +2 more
core   +1 more source

The PLASMIC Score May Be Useful in the Early Diagnosis of Complement-Mediated Thrombotic Microangiopathy via Early Exclusion of Thrombotic Thrombocytopenic Purpura

open access: yesCase Reports in Medicine, 2019
Complement-mediated thrombotic microangiopathy is a rare form of thrombotic microangiopathy but has high rates of mortality and morbidity. Effective treatment exists with eculizumab for this condition, but administration of treatment is often delayed ...
Edwin Lu, Willie Moore
doaj   +1 more source

Safe and Effective Administration of Caplacizumab in COVID-19-Associated Thrombotic Thrombocytopenic Purpura

open access: yesHematology Reports, 2023
Thrombotic thrombocytopenic purpura (TTP) is a potentially life-threatening, rare acute thrombotic microangiopathy (TMA), caused by a severe ADAMTS13 deficiency.
Antonella Bruzzese   +15 more
doaj   +1 more source

Cancer and Thrombotic Microangiopathy [PDF]

open access: yesJournal of Oncology Practice, 2016
Cancer-Associated Thrombotic Microangiopathy Thrombotic microangiopathy (TMA) is a general term that describes the clinical features of thrombocytopenia and microangiopathic hemolytic anemia, in conjunction with a raised lactate dehydrogenase level, reticulocytosis, and often hyperbilirubinemia.
openaire   +2 more sources

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