Results 41 to 50 of about 109,215 (254)
Thrombotic Microangiopathy and the Kidney [PDF]
Clinical Journal of the American Society of Nephrology, 2017 Thrombotic microangiopathy can manifest in a diverse range of diseases and is characterized by thrombocytopenia, microangiopathic hemolytic anemia, and organ injury, including AKI. It can be associated with significant morbidity and mortality, but a systematic approach to investigation and prompt initiation of supportive management and, in some cases ...
Brocklebank V, Wood KM, Kavanagh D
openaire +3 more sources
Assembly and Activation of Alternative Complement Components on Endothelial Cell-Anchored Ultra-Large Von Willebrand Factor Links Complement and Hemostasis-Thrombosis [PDF]
, 2013 Background: Vascular endothelial cells (ECs) express and release protein components of the complement pathways, as well as secreting and anchoring ultra-large von Willebrand factor (ULVWF) multimers in long string-like structures that initiate platelet ...
Moake, Joel, Turner, Nancy A.
core +2 more sources
A case of refractory thrombotic thrombocytopenic purpura treated with plasmapheresis and rituximab [PDF]
, 2016 Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening disorder with no prevalence or incidence studies in sub-Saharan Africa. Acquired TTP has several causes, all of which lead to decreased activity of von Willebrand factor cleaving ...
Kirui, Nicholas, Sokwala, Ahmed
core +4 more sources
The Differential Diagnosis and Treatment of Thrombotic Microangiopathies. [PDF]
Dtsch Arztebl Int, 2018 Bommer M +3 more
europepmc +2 more sources
Frontiers in Immunology, 2019 Thrombotic microangiopathies (TMAs) are a heterogeneous group of syndromes presenting with a distinct clinical triad: microangiopathic hemolytic anemia, thrombocytopenia, and organ damage.
E. Gavriilaki +2 more
semanticscholar +1 more source
Difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unit
Вестник анестезиологии и реаниматологии, 2019 Atypical hemolytic uremic syndrome (aHUS) is an orphan disease, representing one of thrombotic microangiopathies, the natural course of which leads to an unfavorable outcome often accompanied by multiple organ failure in the onset of the disease ...
N. L. Kozlovskаya +2 more
doaj +1 more source
Histopathological features of thrombotic microangiopathies in renal biopsies [PDF]
Journal of Nephropathology, 2019 Background: Thrombotic microangiopathy (TMA) is a morphologic lesion characterized by thrombi occluding microvasculature related to endothelial injury. Objectives: This study aimed to assess the association between histopathological findings and etiology
Miguel Ernandes Neto +5 more
doaj +1 more source
Plasma resistant atypical hemolytic uremic syndrome associated with a CFH mutation treated with eculizumab: a case report [PDF]
, 2015 INTRODUCTION: Thrombotic microangiopathies are a group of diseases presenting as microangiopathic hemolytic anemia, thrombocytopenia and end-organ dysfunction.
Abdulkadir Unsal +11 more
core +1 more source
Case Reports in Medicine, 2019 Complement-mediated thrombotic microangiopathy is a rare form of thrombotic microangiopathy but has high rates of mortality and morbidity. Effective treatment exists with eculizumab for this condition, but administration of treatment is often delayed ...
Edwin Lu, Willie Moore
doaj +1 more source
Hematology Reports, 2023 Thrombotic thrombocytopenic purpura (TTP) is a potentially life-threatening, rare acute thrombotic microangiopathy (TMA), caused by a severe ADAMTS13 deficiency.
Antonella Bruzzese +15 more
doaj +1 more source