Results 31 to 40 of about 3,536 (218)

Epidemiology, Outcomes, and Complement Gene Variants in Secondary Thrombotic Microangiopathies. [PDF]

Clin J Am Soc Nephrol, 2023
BACKGROUND: The identification of complement defects as major drivers of primary atypical hemolytic uremic syndrome (HUS) has transformed the landscape of thrombotic microangiopathies (TMAs), leading to the development of targeted therapies and better ...
Werion A, Werion A, Storms P, Zizi Y, Beguin C, Bernards J, Cambier JF, Dahan K, Dierickx D, Godefroid N, Hilbert P, Lambert C, Levtchenko E, Meyskens T, Poiré X, van den Heuvel L, Claes KJ, Morelle J, UCLouvain TMA/HUS Network and KU Leuven TMA/HUS Network.   +18 more
europepmc   +2 more sources

Physiopathological implications of abnormal Arterial Spin Labeling perfusion in thrombotic microangiopathy

Thrombosis Update, 2021
Thrombotic microangiopathies are a group of clinical syndromes characterized by microangiopathic hemolytic anemia, thrombocytopenia and end-organ damage, which can compromise the central nervous system.
Xavier Merchán-del-Hierro, María-Victoria Camino, Gabriel Persi, Carlos Rugilo, María-Pilar Sánchez-de-Paz, Emilia Gatto   +5 more
doaj   +1 more source

Complement Activation and Thrombotic Microangiopathies. [PDF]

Clin J Am Soc Nephrol, 2019
BACKGROUND AND OBJECTIVES: Atypical hemolytic uremic syndrome is a form of thrombotic microangiopathy caused by dysregulation of the alternative complement pathway.
Palomo M, Blasco M, Molina P, Lozano M, Praga M, Torramade-Moix S, Martinez-Sanchez J, Cid J, Escolar G, Carreras E, Paules C, Crispi F, Quintana LF, Poch E, Rodas L, Goma E, Morelle J, Espinosa M, Morales E, Avila A, Cabello V, Ariceta G, Chocron S, Manrique J, Barros X, Martin N, Huerta A, Fraga-Rodriguez GM, Cao M, Martin M, Romera AM, Moreso F, Manonelles A, Gratacos E, Pereira A, Campistol JM, Diaz-Ricart M.   +36 more
europepmc   +2 more sources

Thrombotic Microangiopathies [PDF]

ISRN Hematology, 2012
Thrombotic microangiopathy results from thrombotic occlusion of the microvasculature leading to fragmentation of red blood cells, profound thrombocytopenia, and a microangiopathic hemolytic anemia with elevation of lactate dehydrogenase and negative direct Coomb’s test.
Radhi, Mohamed, Carpenter, Shannon L.
openaire   +2 more sources

Thrombotic Thrombocytopenic Purpura as a Rare Etiopathogenetic Cause of Cerebral Infarction and Extracerebral Thrombosis

Вестник анестезиологии и реаниматологии, 2021
Thrombotic thrombocytopenic purpura is a disease from the group of thrombotic microangiopathies, the early diagnosis of which is a real challenge in clinical practice.
А. R. Аvidzba, V. A. Saskin, E. V. Nedashkovskiy   +2 more
doaj   +1 more source

Thrombotic microangiopathies postrenal transplantation

Indian Journal of Transplantation, 2020
Aims: The aim of the study was to describe 12 cases of thrombotic microangiopathy (TMA) postrenal transplantation and study the causes, treatment, and outcomes.
Kartik Ganesh, Abi M Abraham, Jithin S Kumar, Renu S Paul, Sunita Simon, Nirmal Harshan   +5 more
doaj   +1 more source

COVID-19 and Thrombotic Thrombocytopenic Purpura: A Case Report

International Journal of Hematology-Oncology and Stem Cell Research, 2021
Endothelial injury by toxins, drugs, immune complexes leads to activation of coagulation cascade and thrombosis, which result in platelet consumption and red blood cell injury. These thrombotic microangiopathies can potentially injure numerous organs and
Maryam Darnahal, Hamed Azhdari Tehrani, Mohammad Vaezi, Shirin Haghighi   +3 more
doaj   +1 more source

Complement activation in secondary thrombotic microangiopathies. [PDF]

Nephrol Dial Transplant
Secondary thrombotic microangiopathies (TMAs) represent a heterogeneous group of diseases associated with a high risk of kidney failure and death despite available therapeutic strategies.
Morelle J, Caravaca-Fontan F, Fakhouri F, Frangou E, Bruchfeld A, Floege J, Mirioglu S, Moran SM, Steiger S, Stevens KI, Teng OYK, Aydin S, Java A, Timmermans SAMEG, Kronbichler A.   +14 more
europepmc   +2 more sources

The thrombotic microangiopathies [PDF]

Pediatric Nephrology, 2008
The term thrombotic microangiopathy (TMA) encompasses a group of conditions that are defined by, or result from, a similar histopathological lesion. Hemolytic uremic syndrome (HUS), thrombotic thrombocytopenic purpura (TTP), and several other conditions are associated with TMA.
Copelovitch, Lawrence, Kaplan, Bernard S.   +1 more
openaire   +2 more sources

Near-fatal cocaine intoxication in an infant with thrombotic microangiopathy associated with multiple organ failure

Revista Paulista de Pediatria, 2023
Objective: To report a pediatric case of drug-induced thrombotic microangiopathy caused by cocaine Case description: We report a nine-month-old patient who developed thrombotic microangiopathies after extreme cocaine intoxication, multiple organ ...
Alejandro Donoso Fuentes, Gianfranco Tomarelli Rubio, Camila Ampuero Acuña, Franco Díaz Rubio, Fernando Bracho Milic, Pamela Carrasco Troncoso   +5 more
doaj   +1 more source