Complement Mediated Endothelial Damage in Thrombotic Microangiopathies [PDF]
Front Med (Lausanne), 2022 Thrombotic microangiopathies (TMA) constitute a group of different disorders that have a common underlying mechanism: the endothelial damage. These disorders may exhibit different mechanisms of endothelial injury depending on the pathological trigger ...
Palomo, Marta +5 more
core +4 more sources
Etiology and Outcomes of Thrombotic Microangiopathies [PDF]
Clin J Am Soc Nephrol, 2019 International audienceBackground and objectives - Thrombotic microangiopathies constitute a diagnostic and therapeutic challenge. Secondary thrombotic microangiopathies are less characterized than primary thrombotic microangiopathies (thrombotic ...
Lachot, Sébastien +62 more
core +2 more sources
Complement Activation and Thrombotic Microangiopathies. [PDF]
Clin J Am Soc Nephrol, 2019 BACKGROUND AND OBJECTIVES: Atypical hemolytic uremic syndrome is a form of thrombotic microangiopathy caused by dysregulation of the alternative complement pathway.
Torramade-Moix, Sergi +73 more
core +2 more sources
Thrombotic microangiopathies: An update
Hematology, 2006 Thrombotic microangiopathies (TMA) are microvascular occlusive disorders characterized by hemolytic anemia caused by fragmentation of erythrocytes and thrombocytopenia due to increased platelet aggregation and thrombus formation, eventually leading to disturbed microcirculation with reduced organ perfusion.
Massimo Franchini
exaly +3 more sources
Pathogenic cytokines in thrombotic microangiopathies: molecular insights and therapeutic targets [PDF]
Mol MedThrombotic microangiopathies (TMAs) are a heterogeneous group of disorders characterized by endothelial damage, microvascular thrombosis, thrombocytopenia, and microangiopathic hemolytic anemia.
Emmanuel Ifeanyi Obeagu
core +2 more sources
Ten tips for managing complement-mediated thrombotic microangiopathies (formerly atypical hemolytic uremic syndrome): narrative review [PDF]
BMC NephrolComplement-mediated thrombotic microangiopathies (CM-TMA) are rare and life-threatening disorders characterized by microangiopathic hemolytic anemia, thrombocytopenia, and organ damage.
Pilar Musalem
core +2 more sources
HELLP Syndrome and Differential Diagnosis with Other Thrombotic Microangiopathies in Pregnancy [PDF]
Diagnostics (Basel)Thrombotic microangiopathies (TMAs) comprise a distinct group of diseases with different manifestations that can occur in both pediatric and adult patients.
Marzioni, Daniela +7 more
core +2 more sources
Infection frequently triggers thrombotic microangiopathy in patients with preexisting risk factors : a single-institution experience [PDF]
, 2010 Thrombotic microangiopathies are rare conditions characterized by microangiopathic hemolytic anemia, microthrombi, and multiorgan insult. The disorders, which include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura, are often acute and ...
Douglas, Kenneth W. +4 more
core +4 more sources
Clinical surveillance of thrombotic microangiopathies in Scotland, 2003-2005 [PDF]
, 2008 The prevalence, incidence and outcomes of haemolytic uraemic syndrome (HUS) and thrombotic thrombocytopaenic purpura (TTP) are not well established in adults or children from prospective studies. We sought to identify both outcomes and current management
Todd, W.T.A. +3 more
core +4 more sources
Thrombotic microangiopathy in children [PDF]
Pediatric Nephrology, 2022 The syndrome of thrombotic microangiopathy (TMA) is a clinical-pathological entity characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end organ involvement. It comprises a spectrum of underlying etiologies that may differ in children and adults.
Lilian Monteiro P. Palma +4 more
openaire +3 more sources