Results 21 to 30 of about 3,536 (218)

Extrarenal manifestations of complement mediated thrombotic microangiopathies

Frontiers in Pediatrics, 2014
Thrombotic microangiopathies (TMA) are rare but severe disorders, characterized by endothelial cell activation and thrombus formation leading to hemolytic anemia, thrombocytopenia and organ failure.
Johannes eHofer, Alejandra eRosales, Caroline eFischer, Thomas eGiner   +3 more
doaj   +2 more sources

Thrombotic microangiopathies: An update

Hematology, 2006
Thrombotic microangiopathies (TMA) are microvascular occlusive disorders characterized by hemolytic anemia caused by fragmentation of erythrocytes and thrombocytopenia due to increased platelet aggregation and thrombus formation, eventually leading to disturbed microcirculation with reduced organ perfusion.
Massimo Franchini
exaly   +3 more sources

Diagnostic Testing for Differential Diagnosis in Thrombotic Microangiopathies [PDF]

Turkish Journal of Hematology, 2019
Thrombotic microangiopathies (TMAs) are multiple disease entities with different etiopathogeneses, characterized by thrombocytopenia, microangiopathic hemolytic anemia (MAHA) with schistocytosis, variable symptoms including fever, and multi-organ failure
Gina Zini, Raimondo De Cristofar
doaj   +2 more sources

Emerging Novel Etiology for Thrombotic Microangiopathies: COVID-19 Infection

Turkish Journal of Nephrology, 2022
Kübra Kaynar, Beyhan Güvercin, Gülcan Varol, Nilay Turan, Alirıza Pektaş   +4 more
doaj   +2 more sources

Thrombotic microangiopathies: First report of 294 cases from a single institution experience in Argentina [PDF]

EJHaem, 2021
Celia Dos Santos, Juvenal Paiva, Maria Fabiana Alberto   +2 more
exaly   +2 more sources

Immune-mediated thrombotic thrombocytopenic purpura plasma induces calcium- and IgG-dependent endothelial activation: correlations with disease severity

Haematologica, 2022
Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by a severe ADAMTS13 deficiency due to the presence of anti-ADAMTS13 auto-antibodies, with subsequent accumulation of circulating ultra-large von Willebrand factor (VWF ...
Edwige Tellier, Agnès Widemann, Raphaël Cauchois, Julien Faccini, Marie Lagarde, Marion Brun, Philippe Robert, Stéphane Robert, Richard Bachelier, Pascale Poullin, Elien Roose, Karen Vanhoorelbeke, Paul Coppo, Françoise Dignat-George, Gilles Kaplanski   +14 more
doaj   +1 more source

Etiology and Outcomes of Thrombotic Microangiopathies. [PDF]

Clin J Am Soc Nephrol, 2019
International audienceBackground and objectives - Thrombotic microangiopathies constitute a diagnostic and therapeutic challenge. Secondary thrombotic microangiopathies are less characterized than primary thrombotic microangiopathies (thrombotic ...
Bayer G, von Tokarski F, Thoreau B, Bauvois A, Barbet C, Cloarec S, Mérieau E, Lachot S, Garot D, Bernard L, Gyan E, Perrotin F, Pouplard C, Maillot F, Gatault P, Sautenet B, Rusch E, Buchler M, Vigneau C, Fakhouri F, Halimi JM.   +20 more
europepmc   +2 more sources

Pathogenic cytokines in thrombotic microangiopathies: molecular insights and therapeutic targets. [PDF]

Mol Med
Thrombotic microangiopathies (TMAs) are a heterogeneous group of disorders characterized by endothelial damage, microvascular thrombosis, thrombocytopenia, and microangiopathic hemolytic anemia.
Obeagu EI.
europepmc   +2 more sources

Thrombotic microangiopathy in children [PDF]

Pediatric Nephrology, 2022
The syndrome of thrombotic microangiopathy (TMA) is a clinical-pathological entity characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end organ involvement. It comprises a spectrum of underlying etiologies that may differ in children and adults.
Lilian Monteiro P. Palma, Maria Helena Vaisbich-Guimarães, Meera Sridharan, Cheryl L. Tran, Sanjeev Sethi   +4 more
openaire   +3 more sources

Pitfalls of Thrombotic Microangiopathies in Children: Two Case Reports and Literature Review. [PDF]

Diagnostics (Basel), 2023
Thrombotic microangiopathy can present itself in the form of several clinical entities, representing a real challenge for diagnosis and treatment in pediatric practice.
Mocanu A, Bogos RA, Lazaruc TI, Cianga AL, Lupu VV, Ioniuc I, Alecsa M, Lupu A, Ivanov AV, Miron IC, Starcea IM.   +10 more
europepmc   +2 more sources