Results 41 to 50 of about 156,099 (292)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Secagem da linguiça calabresa: experimentação e modelagem 3D aplicadas a fornos industriais [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Química, Florianópolis, 2009Esta investigação científica tem por objetivo o desenvolvimento de uma metodologia computacional capaz de ...
Piaia, Julio Cesar Zanchet
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Comparison on Modelling of Drying Kinetics of Granular Polymers PA6 by Diffusion Models and Normalization Method [PDF]

open access: yes, 2012
In this work, the drying behaviour of single granular PA6, hanging in the flow direction of hot air in a drying chamber, was investigated. In the experiments, the air was passed through the chamber at contant very low velocity in the drying chamber of ...
S, Suherman   +2 more
core  

Effect of temperature and mode of drying on bioactive compounds and quality of germinated parboiled rice [PDF]

open access: yes, 2018
[EN] Germinated parboiled rice (GPR) is recognized as a functional food because it is rich in bioactive compounds, especially gamma-aminobutyric acid (GABA).
Nagle, Marcus   +7 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Modeling and simulation of drying operation in PVC powder production line: a pneumatic dryer model [PDF]

open access: yes, 2012
A one-dimensional steady-state model is developed to simulate drying of PVC powder in a pneumatic dryer. In this model, a two-phase continuum model was used to describe the steady-state flow of a dilute dispersed phase (wet PVC powder) and a continuous ...
Ansart, Renaud   +4 more
core  

Effect of hot air temperature on drying kinetics of palmyra (Borassus aethiopum Mart.) seed-sprout fleshy scale slices and quality attributes of its flour

open access: yesJournal of Agriculture and Food Research, 2021
This study investigated the influence of different drying air temperatures (40, 50, 60 and 70 °C) on moisture removal ratio and drying rate of pre-cooked and uncooked palmyra (Borassus aethiopum) seed-sprout fleshy scale (SFS) slices and quality of the ...
Joseph Kudadam Korese   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

PENGERING SUMBER ENERGI BIOMASSA SABUT KELAPA MENINGKATKAN PENGHASILAN PERAJIN IKAN TERI SKALA RUMAH TANGGA

open access: yesAgrointek, 2021
The process of drying anchovy traditionally causes the temperature and drying time to be suboptimal. This affects the income of anchovy fish processing workers.
I Gede Bawa Susana, Ida Bagus Alit
doaj   +1 more source

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