Results 91 to 100 of about 1,675 (176)

Membranous Nephropathy and Anti-Podocytes Antibodies: Implications for the Diagnostic Workup and Disease Management [PDF]

, 2018
The discovery of circulating antibodies specific for native podocyte antigens has transformed the diagnostic workup and greatly improved management of idiopathic membranous nephropathy (iMN).
Goujon, Jean-Michel, Agnieszka Pozdzik, Fahd Touzani, Pozdzik, Agnieszka, Touzani, Fahd, Wissing, Karl Martin, Brochériou, Isabelle, David, Cristina, Isabelle Brochériou, Karl Martin Wissing, Cristina David, Jean Michel Goujon   +11 more
core   +1 more source

Genome-Wide Association and Functional Studies Identify SCML4 and THSD7A as Novel Susceptibility Genes for Coronary Artery Disease

, 2018
Objective— The genetic contribution to coronary artery disease (CAD) remains largely unclear. We combined genetic screening with functional characterizations to identify novel loci and candidate genes for CAD.
Yan Yao, Feng Jiang, Zhijun Sun, Yundai Chen, Dao Wen Wang, Bin Zhao, Ke Xu, Chun Song, Xiangfeng Lu, Heribert Schunkert, Shuhan Tian, Wen-Jing Wang, Yuehua Ma, Gangqiong Liu, Jie Dong, Lijuan Jin, Can Chen, Fan Yang, Guyan Zheng, Changhua Wang, Linyao Zeng, Jian Guo, Yanjun Cui, Shenghan Chen, Chong Wu, Wei Lei, Jianfeng Zhong, Xueli Yang, Lei Zhou, Shenghuang Wang, Jeanette Erdmann, Hanbin Cui, Shu Zhang, Wenjiang Chen, Yang Li, Xiao-Li Tian, Shaoqi Rao, Dongfeng Gu, Hu Ding, Shian Huang, Jianli Sun, Han Yan   +41 more
core   +1 more source

Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in CD46 and other loci

Epigenetics
The cortical epigenetic clock was developed in brain tissue as a biomarker of brain aging. As one way to identify mechanisms underlying aging, we conducted a GWAS of cortical age.
Francine Grodstein, Bernardo Lemos, Jingyun Yang, Katia de Paiva Lopes, Ricardo A. Vialle, Nicholas Seyfried, Yanling Wang, Gemma Shireby, Eilis Hannon, Alan Thomas, Keeley Brookes, Jonathan Mill, Philip L. De Jager, David A. Bennett   +13 more
doaj   +1 more source

Additional file 2: Figure S1. of Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway

, 2016
Comprehensive in situ hybridization analysis of thsd7a expression to different neuronal markers. The expression of different neuronal markers include nestin (progenitor cells of nervous system)、olig2 (oligodendrocyte)、gfap (glial fibrillary acidic ...
Lawrence Liu (3458792), Min-Hsuan Lin (113008), Jie-Peng Jiang (3458795), Li-En Jao (3458801), Yung-Jen Chuang (186923), Yi-Ching Huang (3458798), Zih-Yin Lai (3458804)   +6 more
core   +1 more source

Characteristics of idiopathic membranous nephropathy (MN) patients with enhanced granular expression of thrombospondin type-1 domain-containing 7A (THSD7A) or M-type phospholipase A2 receptor (PLA2R) in the glomeruli.

, 2015
Characteristics of idiopathic membranous nephropathy (MN) patients with enhanced granular expression of thrombospondin type-1 domain-containing 7A (THSD7A) or M-type phospholipase A2 receptor (PLA2R) in the glomeruli.
Hideo Yasuda (710367), Satoshi Baba (540358), Naro Ohashi (168272), Akihiko Kato (798462), Takamasa Iwakura (798461)   +4 more
core   +1 more source

Vascular threads and nephron nests: exploring the association between Takayasu arteritis and membranous nephropathy

European Journal of Case Reports in Internal Medicine
Takayasu arteritis (TA) primarily causes ischaemic nephrosclerosis but can occasionally be associated with glomerulopathy. We report a case of a female in her twenties with PLA2-negative, THSD7A-positive membranous nephropathy (MN) refractory to ...
Sameen Aamer, Anand Rajan, Swati Arora
doaj   +1 more source

THSD7A, the second autoantigen in membranous nephropathy : new diagnostic test and identification of the immunodominant epitopes

, 2019
La glomérulonéphrite extra–membraneuse (GEM) est une maladie auto–immune rénale rare et une des causes principales de syndrome néphrotique chez l'adulte.
Zaghrini, Kristel
core  

Human anti-thrombospondin type 1 domain-containing 7A antibodies induce membranous nephropathy through activation of lectin complement pathway

, 2018
To investigate whether the human anti-thrombospondin type 1 domain-containing 7A (THSD7A) antibody-induced membranous nephropathy (MN) is mediated by activating lectin complement pathway.
Zheng Wang, Yanna Dou, Lu Wen, Zhanzheng Zhao   +3 more
core   +1 more source

Novel ELISA for thrombospondin type 1 domain-containing 7A autoantibodies in membranous nephropathy

, 2019
International audienceAutoantibodies against phospholipase A2 receptor 1 (PLA2R1) and thrombospondin type 1 domain-containing 7A (THSD7A) are emerging as biomarkers to classify membranous nephropathy (MN) and to predict outcome or response to treatment ...
Lonnbro-Widgren, Jennie, Ghiggeri, Gianmarco, Jourde-Chiche, Noemie, Seitz-Polski, Barbara,, Cui, Zhao, Zaghrini, Christelle, Nystrom, Jenny, Ronco, Pierre, Seitz-Polski, Barbara, Seitz, Mariat, Christophe, Payre, Christine, Wetzels, Jack F.M., Rigby, Emma, Seitz-Polski, Barbara, van de Logt, Anne-Els, Beck, Laurence, Justino, Joana, Dolla, Guillaume, Booth, Caroline, Debiec, Hanna, Lambeau, Gérard   +20 more
core   +1 more source

ISEV2025 Abstract Book

Journal of Extracellular Vesicles, Volume 14, Issue S1, October 2025.
wiley   +1 more source