Results 71 to 80 of about 1,675 (176)
Additional file 2: of Expression of THSD7A in neoplasm tissues and its relationship with proteinuria
, 2019 Figure S1. The classification criteria for histochemical staining intensity. A-C is the three categories of THSD7A staining intensity in colorectal cancer tissues: A, 3+; B, 2+; C, 1+.
Gang Xu (219455) +10 more
core +1 more source
, 2015 Immunostaining for THSD7A (a, c, e) and PLA2R (b, d, f) in patients with idiopathic membranous nephropathy (a–d) and secondary membranous nephropathy (e, f). Original magnification: ×400.
Hideo Yasuda (710367) +4 more
core +1 more source
Nephrology, Volume 30, Issue 9, September 2025.ABSTRACT Aim The KDIGO 2021 Glomerular Disease Guidelines provide updated recommendations on the management of glomerular diseases (GD), with substantial advances made in diagnosis, treatment, and improvement of outcomes for people with GD. Methods The Caring for Australians and New Zealanders with kidney Impairment (CARI) Guidelines commentary ...
Bhadran Bose +28 more
wiley +1 more source
Acta Physiologica, Volume 241, Issue 8, August 2025.ABSTRACT Aim Podocytes, highly specialized epithelial cells located in the glomerulus of the kidney, are essential to the filtration barrier that ensures separation of blood and urine. These cells exhibit a unique architecture, characterized by an intricate network of foot processes interconnected by slit diaphragms, which serve as a critical selective
Desiree Loreth +2 more
wiley +1 more source
International Journal of Clinical Practice, 2020 Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in nondiabetic adults. M-type phospholipase A2 receptor (PLA2R), thrombospondin type-1 domain-containing 7A (THSD7A) are known as target podocyte antigens in membranous nephropathy (MN).
Bulent Kaya +4 more
openaire +2 more sources
Contemporary Perspectives on Chronic Renal Disorders
Chronic Diseases and Translational Medicine, Volume 11, Issue 2, Page 89-104, June 2025.ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok +5 more
wiley +1 more source
Frontiers in Immunology, 2020 Idiopathic membranous nephropathy (IMN) is a pathological pattern of glomerular damage caused by an autoimmune response. Immune complex deposition, thickness of glomerular basement membrane, and changes in the podocyte morphology are responsible for the ...
Wenbin Liu +9 more
doaj +1 more source
Biology of the Cell, Volume 117, Issue 6, June 2025.Protrusion‐derived extracellular vesicles (PD‐EVs) driving tumor progression and immune modulation. PD‐EVs arise from dynamic cellular extensions and serve as powerful communication tools. In cancer, they reshape the tumor microenvironment, promote angiogenesis and metastasis, and modulate immune responses, including T cell activation.
Mireia Gomez Duro +4 more
wiley +1 more source
Prediagnostic Appearance of THSD7A Autoantibodies in Membranous Nephropathy
, 2022 Background: Pathogenic autoantibodies against thrombospondin type-1 domain 7A (THSD7A) are present in approximately 3% of patients with membranous nephropathy (MN). Compared to PLA2R antibodies, less is known about THSD7A autoantibodies (AB) due to the relative rarity and lack of a commercially, available quantitative immunoassay.
Burbelo, Peter +8 more
openaire +1 more source
Comparative mapping of single‐cell transcriptomic landscapes in neurodegenerative diseases
Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.Abstract INTRODUCTION Alzheimer's disease (AD), dementia with Lewy bodies (DLB), and Parkinson's disease (PD) represent a spectrum of neurodegenerative diseases (NDDs). Here, we performed the first direct comparison of their transcriptomic landscapes.
E. Keats Shwab +9 more
wiley +1 more source