Results 71 to 80 of about 1,835 (171)
Additional file 1: of Expression of THSD7A in neoplasm tissues and its relationship with proteinuria
Table S1. Detailed information about patients with positive urinary protein M, male; F, female. Table S2. Correlation between urinary protein and THSD7A staining intensity of in colorectal cancer group.
Gang Xu (219455) +10 more
core +1 more source
Cortical RORβ is required for layer 4 transcriptional identity and barrel integrity
Retinoic acid-related orphan receptor beta (RORβ) is a transcription factor (TF) and marker of layer 4 (L4) neurons, which are distinctive both in transcriptional identity and the ability to form aggregates such as barrels in rodent somatosensory cortex.
Erin A Clark +12 more
doaj +1 more source
Introduction The association between membranous nephropathy (MN) and malignant neoplasms has been extensively studied in recent decades and is well established in the literature. Although PLA2R is the main target antigen in primary MN, there remain uncertainties regarding a possible connection between malignancy and anti‐PLA2R positivity.
Fabiano Bichuette Custodio +5 more
wiley +1 more source
Additional file 2: of Expression of THSD7A in neoplasm tissues and its relationship with proteinuria
Figure S1. The classification criteria for histochemical staining intensity. A-C is the three categories of THSD7A staining intensity in colorectal cancer tissues: A, 3+; B, 2+; C, 1+.
Gang Xu (219455) +10 more
core +1 more source
This is the first detailed report of spontaneous remission of late relapsing membranous nephropathy (MN) after previous immunosuppressant‐induced remission. In March 2004, a 52‐year‐old Hispanic male presented with severe nephrotic syndrome with proteinuria of 13 g/24 h. The workup for infectious and autoimmune diseases was unrevealing.
Yangming Cao, Poorani Gurumallesh Prabu
wiley +1 more source
Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in nondiabetic adults. M-type phospholipase A2 receptor (PLA2R), thrombospondin type-1 domain-containing 7A (THSD7A) are known as target podocyte antigens in membranous nephropathy (MN).
Bulent Kaya +4 more
openaire +2 more sources
Exostosin‐2 (EXT2)‐associated membranous nephropathy (MN) represents a subgroup of immune complex‐mediated renal diseases, where transplantation may facilitate clearance of immune deposits. We present a successful kidney transplantation from a 19‐year‐old deceased donor with previously undiagnosed EXT2‐associated MN into a 75‐year‐old male recipient ...
Mike Fruscione +7 more
wiley +1 more source
Prediagnostic Appearance of THSD7A Autoantibodies in Membranous Nephropathy
Background: Pathogenic autoantibodies against thrombospondin type-1 domain 7A (THSD7A) are present in approximately 3% of patients with membranous nephropathy (MN). Compared to PLA2R antibodies, less is known about THSD7A autoantibodies (AB) due to the relative rarity and lack of a commercially, available quantitative immunoassay.
Burbelo, Peter +8 more
openaire +1 more source
The current study characterized temporal changes in glomerular gene expression, pathology, and biomarkers in a mouse model of hypertension‐accelerated diabetic kidney disease (DKD). Progressive albuminuria and glomerulosclerosis were paralleled by dynamic transcriptomic changes associated withmetabolic dysfunction, extracellular matrix remodeling, and ...
Adam B. Marstrand‐Jørgensen +8 more
wiley +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source

