Results 61 to 70 of about 1,835 (171)
PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni +5 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT The coexistence of primary phospholipase A2 receptor positive membranous nephropathy and AA amyloidosis in a patient with chronic hepatitis B is an exceedingly rare triad presenting a profound diagnostic and therapeutic challenge. A 38‐year‐old Ethiopian man with nephrotic syndrome and chronic hepatitis B had dual pathology on renal biopsy ...
Betelhem Abreham +4 more
wiley +1 more source
Journal of Orthopaedic Research, Volume 44, Issue 3, March 2026.ABSTRACT Rotator cuff tear (RCT) is a prevalent age‐related condition whose underlying mechanisms remain poorly understood. This study employed spatial transcriptomics and multiplex immunofluorescence (mIF) to investigate gene expression and spatial heterogeneity in rotator cuff tissues from elderly RCT patients compared to age‐matched controls, aiming
Shiyi Yao +9 more
wiley +1 more source
Examples of positive and negative staining for THSD7A, PLA2R, and IgG4.
, 2015 Positive staining for THSD7A (a, b), PLA2R (e, f), and IgG4 (i, j), and negative staining for THSD7A (c, d), PLA2R (g, h), and IgG4 (k, l) are shown.
Hideo Yasuda (710367) +4 more
core +1 more source
Case Report: THSD7A-Positive Membranous Nephropathy Caused by Tislelizumab in a Lung Cancer Patient
Frontiers in Immunology, 2021 Immune checkpoint inhibitors (ICIs) became the standard treatment for many different kinds of cancers and can result in a variety of immune-related adverse events (irAEs). IrAEs of kidney are uncommon and consists of different pathology types.
Minjiang Chen +5 more
doaj +1 more source
Antigenic Spectrum in Membranous Nephropathy: A Comprehensive Analysis of PLA2R, THSD7A, and NELL-1. [PDF]
Indian J NephrolJain A +9 more
europepmc +3 more sources
Advanced Science, Volume 13, Issue 1, 5 January 2026.Single‐nucleus RNA sequencing of mid‐gestation brains from fetuses with nonsyndromic cleft lip and palate reveals major disruptions in cell composition, cell‐to‐cell signaling, and gene regulation. The transcription factor MEF2C is identified as a central regulator of these changes and shows that lowering MEF2C impairs synapse formation, linking cleft ...
Liu‐Lin Xiong +19 more
wiley +1 more source
, 2019 Membranous nephropathy (MN) is a rare autoimmune kidney disease with an incidence of 1.3/100,000 in Europe yet it is a leading cause of nephrotic syndrome in adults.
Zaghrini, Kristel
core +2 more sources
Aging Cell, Volume 25, Issue 1, January 2026.Our single nuclei RNA sequencing data reveal that long‐term calorie restriction in aged rhesus monkeys reduces neuroinflammation and preserves glial metabolism. In oligodendrocytes, calorie restriction attenuates an immune signature and promotes axonal proximity, while reducing a myelin‐laden microglia population.
Ana T. Vitantonio +13 more
wiley +1 more source
Case Reports in Medicine, Volume 2026, Issue 1, 2026.Immunoglobulin G4–related disease (IgG4‐RD) is a chronic fibroinflammatory disorder affecting multiple organs, including the kidneys. Ulcerative colitis (UC) is an immune‐mediated colonic disease. Their coexistence is uncommon, especially when UC is not IgG4 associated.
Liping Xu +4 more
wiley +1 more source