Results 41 to 50 of about 1,835 (171)

Highly Expressing SCARA5 Promotes Proliferation and Migration of Esophageal Squamous Cell Carcinoma

Journal of Immunology Research, 2022
Background. Thrombospondin type 1 domain-containing 7A (THSD7A) was reported to play a procancer role in esophageal squamous cell carcinoma (ESCC). The aim of the study was to screen the downstream functional genes of THSD7A and explore their functions ...
Kawuli Jumai, Tangjuan Zhang, Bingzhang Qiao, Julaiti Ainiwaer, Haiping Zhang, Zhichao Hou, Idris Awut, Madinyat Niyaz, Liwei Zhang, Ilyar Sheyhidin   +9 more
doaj   +1 more source

First Report of Daratumumab Therapy in Refractory THSD7A-Positive Membranous Nephropathy. [PDF]

Kidney Int Rep
Ribes D, Faguer S.
europepmc   +3 more sources

SCARA5 Is Overexpressed in Prostate Cancer and Linked to Poor Prognosis

Diagnostics, 2023
Prostate cancer is one of the most common malignancies worldwide, showing a wide range of clinical behaviors. Therefore, several treatment options arise out of the diagnosis “prostate cancer”. For this reason, it is desirable to find novel prognostic and
Fidelis Andrea Flockerzi, Johannes Hohneck, Matthias Saar, Rainer Maria Bohle, Phillip Rolf Stahl   +4 more
doaj   +1 more source

THSD7A expression: a novel immunohistochemical determinant in predicting overall survival of metastatic renal cell carcinoma treated with targeted therapy

, 2021
Background: The association of thrombospondin type 1 domain-containing 7A (THSD7A) expression, a novel angiogenesis-related marker, with survival outcomes of tumors including renal cell carcinoma (RCC) remains to be clarified.
KÖSEMEHMETOĞLU, KEMAL, Sahin, Taha Koray, GÜVEN, DENİZ CAN, Gundogdu, Fatma, YETER, HACI HASAN, DİZDAR, ÖMER, Erman, Mustafa, Yuce, Deniz, KERTMEN, NEYRAN, AKSOY, SERCAN, Yalcin, Suayib, Aktepe, OKTAY HALİT, Fatma Gundogdu, Neyran Kertmen, Deniz Yuce, Haci Hasan Yeter, Taha Koray Sahin, Suayib Yalcin, Oktay Halit Aktepe, Omer Dizdar, Sercan Aksoy, Mustafa Erman, Kemal Kosemehmetoglu, Deniz Can Guven   +23 more
core   +1 more source

Prevalence of neural epidermal growth factor-like 1- and exostosin 1/exostosin 2-associated membranous nephropathy: a single-center retrospective study in Japan

Scientific Reports, 2022
Membranous nephropathy (MN) is the leading cause of nephrotic syndrome in adults. We previously reported that the prevalence of phospholipase A2 receptor (PLA2R)- and thrombospondin type 1 domain containing 7A (THSD7A)-associated MN patients in Japan is ...
Takamasa Iwakura, Chiemi Ema, Shinsuke Isobe, Tomoyuki Fujikura, Naro Ohashi, Akihiko Kato, Hideo Yasuda   +6 more
doaj   +1 more source

Mechanisms of Primary Membranous Nephropathy

Biomolecules, 2021
Membranous nephropathy (MN) is an autoimmune disease of the kidney glomerulus and one of the leading causes of nephrotic syndrome. The disease exhibits heterogenous outcomes with approximately 30% of cases progressing to end-stage renal disease.
Yan Gu, Hui Xu, Damu Tang
doaj   +1 more source

Clinical Study of THSD7A, SOD2 and AR Antigens in Idiopathic Membranous Nephropathy [PDF]

, 2021
Abstract Background To explore the expression of THSD7A, SOD2 and AR podocyte antigens in the renal tissue of patients with idiopathic membranous nephropathy (IMN) and its clinical diagnostic value in IMN. Method This study retrospectively collected 150 renal tissue specimens and clinical data of patients undergoing renal biopsy in the ...
Honggang Wang, Tingting Zhao, Jianwei Dong, Yan Zhou, Jing Huang, Caifeng Gao, Lei Chen, Jiatong Li, Rong Wang, Bing Chen   +9 more
openaire   +1 more source

Recurrent membranous nephropathy with a possible alteration in the etiology: a case report

BMC Nephrology, 2021
Background Phospholipase A2 receptor 1 (PLA2R1) and thrombospondin type-1 domain-containing 7A (THSD7A) are the two major pathogenic antigens for membranous nephropathy (MN).
Ayumi Matsumoto, Isao Matsui, Keiji Mano, Hitoshi Mizuno, Yusuke Katsuma, Seiichi Yasuda, Karin Shimada, Kazunori Inoue, Takashi Oki, Tadashi Hanai, Keiko Kojima, Tetsuya Kaneko, Yoshitaka Isaka   +12 more
doaj   +1 more source

Refractory THSD7A membranous nephropathy with severe asthma related to eosinophilia

Clinical Nephrology, 2019
We report a case of a 50-year-old Japanese man with a history of pediatric asthma diagnosed with nephrotic syndrome after 4 years of relapsing asthma with severe eosinophilia. Thrombospondin type-1 domain-containing 7A membranous nephropathy (THSD7A-MN) was diagnosed based on histological evaluation.
Tomo, Suzuki, Shu, Ushimaru, Daisuke, Uchida, Shiika, Watanabe, Daisuke, Ichikawa, Junki, Koike, Hidehiko, Mizuguchi, Hiroo, Kawarazaki, Yugo, Shibagaki   +8 more
openaire   +3 more sources

Determination of Anti-Phospholipase A2 and Anti-Thrombospondin Type 1 Domain-Containing Protein 7A in Latin Patients with Membranous Nephropathy

Diagnostics, 2022
Primary membranous nephropathy (MN) is caused by antibodies against podocyte antigens, especially the type M receptor of phospholipase A2 (PLA2R) and thrombospondin type-1 domain containing 7 A (THSD7A).
Ligia C. Battaini, Otavio T. Ranzani, Lia J. Marçal, Leila Antonangelo, Lecticia B. Jorge, Cristiane D. Bitencourt, Victoria Woronik, Denise M. A. Malheiros, Luis Yu   +8 more
doaj   +1 more source