Results 31 to 40 of about 1,675 (176)

First Report of Daratumumab Therapy in Refractory THSD7A-Positive Membranous Nephropathy. [PDF]

Kidney Int Rep
Ribes D, Faguer S.
europepmc   +3 more sources

A membranous nephropathy variant mimicking minimal change disease. [PDF]

J Pathol Clin Res
Abstract This study characterizes a novel disease pattern of membranous nephropathy (MN) that exhibits overlapping clinicopathological features with minimal change disease (MCD), termed ‘MCD‐like MN’. Patients with histologically confirmed MN showing sparse and segmental subepithelial electron‐dense deposits (EDD) but clinically resembling MCD were ...
Pan C, Xiang S, Jiang M, Li Y, Huang B, Ye T, Du Y, Tang X, Yuan Y.   +8 more
europepmc   +2 more sources

Clinical significance of the determination of antibodies to thrombospondin type 1 containing domain 7A (THSD7A) in membranous nephropathy

Терапевтический архив, 2023
Background. Membranous nephropathy (MN) is an immunocomplex glomerular disease, which is the most common cause of nephrotic syndrome in adults. Numerous studies have established that autoantibodies against the target podocyte autoantigens, including the ...
Patimat A. Kakhsurueva, Elena S. Kamyshova, Irina N. Bobkova, Ekaterina V. Stavrovskaya, Tatiana E. Rudenko, Elena Y. Andreeva   +5 more
doaj   +1 more source

Profile of Indian Patients With Membranous Nephropathy

Kidney International Reports, 2020
Introduction: The majority of primary membranous nephropathy (MN) cases are no longer considered idiopathic with the discovery of the podocytic autoantigens: phospholipase A2 receptor (PLA2R) and thrombospondin type 1 domain–containing 7A (THSD7A ...
Priyadarsani Subramanian, Hemanth Kumar, Bipin Tiwari, Adarsh Barwad, Soumita Bagchi, Arvind Bagga, Sanjay Kumar Agarwal, Amit Kumar Dinda, Geetika Singh   +8 more
doaj   +1 more source

Antigenic Spectrum in Membranous Nephropathy: A Comprehensive Analysis of PLA2R, THSD7A, and NELL-1. [PDF]

Indian J Nephrol
Jain A, Tiwari V, Gupta A, Gupta P, Deb R, Bhargava V, Malik M, Gupta A, Bhalla AK, Rana DS.   +9 more
europepmc   +3 more sources

Upregulated LncZBTB39 in preeclampsia and Its effects on trophoblast invasion and migration via antagonizing the inhibition of miR-210 on THSD7A expression [PDF]

, 2020
ObjectivePre-eclampsia (PE) is a major cause of maternal morbidity and mortality, but its etiology remains to be elucidated. Accumulating evidence suggests that placental long noncoding RNAs (lncRNAs) might contribute to the pathogenesis of pre-eclampsia.
Kilby, Mark, Tian, Jing
core   +4 more sources

Investigation of Genomic and Transcriptomic Risk Factors of Clopidogrel Response in African Americans. [PDF]

Clin Pharmacol Ther
Clopidogrel, an anti‐platelet drug, is used to prevent thrombosis after percutaneous coronary intervention. Clopidogrel resistance results in recurring ischemic events, with African Americans (AA) suffering disproportionately. The aim of this study was to discover novel biomarkers of clopidogrel resistance in African Americans using genome and ...
Yang G, Alarcon C, Chanfreau C, Lee NH, Friedman P, Nutescu E, Tuck M, O'Brien T, Gong L, Klein TE, Chang KM, Tsao PS, Meltzer DO, Lynch JA, Million Veteran Program, Tuteja S, Perera MA.   +16 more
europepmc   +2 more sources

THSD7A expression: a novel immunohistochemical determinant in predicting overall survival of metastatic renal cell carcinoma treated with targeted therapy

, 2022
Background: The association of thrombospondin type 1 domain-containing 7A (THSD7A) expression, a novel angiogenesis-related marker, with survival outcomes of tumors including renal cell carcinoma (RCC) remains to be clarified.
KÖSEMEHMETOĞLU, KEMAL, Sahin, Taha Koray, GÜVEN, DENİZ CAN, Gundogdu, Fatma, YETER, HACI HASAN, DİZDAR, ÖMER, Erman, Mustafa, Yuce, Deniz, KERTMEN, NEYRAN, AKSOY, SERCAN, Yalcin, Suayib, Aktepe, OKTAY HALİT   +11 more
core   +1 more source

Primary Membranous Nephropathy With Enhanced Staining of Exostosin 1/Exostosin 2 in the Glomeruli: A Report of 2 Cases

Kidney Medicine, 2021
Technological advances have allowed the discovery of 6 subtypes of membranous nephropathy based on target antigens: M-type phospholipase A2 receptor (PLA2R), thrombospondin type 1 domain-containing 7A (THSD7A), neural epidermal growth factor-like 1 ...
Takamasa Iwakura, Chiemi Ema, Taichi Sato, Shinsuke Isobe, Tomoyuki Fujikura, Naro Ohashi, Akihiko Kato, Hideo Yasuda   +7 more
doaj   +1 more source

Highly Expressing SCARA5 Promotes Proliferation and Migration of Esophageal Squamous Cell Carcinoma

Journal of Immunology Research, 2022
Background. Thrombospondin type 1 domain-containing 7A (THSD7A) was reported to play a procancer role in esophageal squamous cell carcinoma (ESCC). The aim of the study was to screen the downstream functional genes of THSD7A and explore their functions ...
Kawuli Jumai, Tangjuan Zhang, Bingzhang Qiao, Julaiti Ainiwaer, Haiping Zhang, Zhichao Hou, Idris Awut, Madinyat Niyaz, Liwei Zhang, Ilyar Sheyhidin   +9 more
doaj   +1 more source