Results 81 to 90 of about 1,835 (171)

Idiopathic Membranous Nephropathy: Glomerular Pathological Pattern Caused by Extrarenal Immunity Activity

Frontiers in Immunology, 2020
Idiopathic membranous nephropathy (IMN) is a pathological pattern of glomerular damage caused by an autoimmune response. Immune complex deposition, thickness of glomerular basement membrane, and changes in the podocyte morphology are responsible for the ...
Wenbin Liu, Chang Gao, Zhiyuan Liu, Haoran Dai, Zhendong Feng, Zhaocheng Dong, Yang Zheng, Yu Gao, Xuefei Tian, Baoli Liu   +9 more
doaj   +1 more source

Genetics of Response to ECT, TMS, Ketamine and Esketamine

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 198, Issue 7, Page 88-102, October 2025.
ABSTRACT Treatment‐resistant mood disorders are often managed with intensive interventions that include electroconvulsive therapy (ECT), transcranial magnetic stimulation (TMS), ketamine, and esketamine, but the role of genetics in clinical response to those interventions is yet to be clearly determined.
Clio E. Franklin, Murat Altinay, Kala Bailey, Mahendra T. Bhati, Brent R. Carr, Susan K. Conroy, Khurshid Khurshid, William M. McDonald, Brian J. Mickey, James W. Murrough, Sean M. Nestor, Thomas Nickl‐Jockschat, Irving M. Reti, Gerard Sanacora, Nicholas T. Trapp, Biju Viswanath, Jesse H. Wright, Peter P. Zandi, James B. Potash   +18 more
wiley   +1 more source

Clinicopathological features in membranous nephropathy with cancer: A retrospective single-center study and literature review

The International Journal of Biological Markers, 2019
Background: Membranous nephropathy is the most common glomerular disease related to malignancy. However, it is difficult to distinguish between true malignancy-related membranous nephropathy and idiopathic membranous nephropathy coincident with cancer ...
Dan Zhang, Chong Zhang, Fan Bian, Wenzhu Zhang, Gengru Jiang, Jun Zou   +5 more
doaj   +1 more source

Circulating Antibodies against Thrombospondin Type-I Domain-Containing 7A in Chinese Patients with Idiopathic Membranous Nephropathy

, 2017
Background and objectives Thrombospondin type-I domain containing 7A (THSD7A) was recently identified as the target antigen in about 10% of patients with M-type phospholipase A2 receptor (PLA2R) negative membranous nephropathy in European and North ...
Liu, Gang, Probst, Christian, Cui, Zhao, Pierre Ronco, Wang, Xin, Ronco, Pierre, Hanna Debiec, Fang Wang, Zhao Cui, Xin Wang, Ming-hui Zhao, Lu, Jie, Qu, Zhen, Jia Wang, Debiec, Hanna, Jie Lu, Li-qiang Meng, Zhen Qu, Christian Probst, Yi-miao Zhang, Wang, Jia, Wang, Fang, Gang Liu, Xu-yang Cheng, Cheng, Xu-Yang, Zhao, Ming-Hui, Meng, Li-Qiang, Zhang, Yi-Miao   +27 more
core   +1 more source

Effects of phospholipase A2 receptor and thrombospondin type-1 domain-containing 7A expression in glomerular basement membranes on treatment response and renal outcome in membranous nephropathy

, 2021
Background: The aim of this study was to define the clinicopathologic features of phospholipase A2 receptor (PLA2R) and/or thrombospondin type-1 domain-containing 7A (THSD7A) associated membranous nephropathy(MN) focusing on their impact to disease ...
Karacalik, Ceren, Eraslan, Esra, GÜZ, GALİP, IŞIK GÖNÜL, İPEK, YETER, HACI HASAN, ÖĞÜT, BETÜL, Yeter, Hasan H., Ipek Isik Gonul, Betul Ogut, Hasan H. Yeter, Galip Guz, Esra Eraslan, Ceren Karacalik   +12 more
core   +1 more source

The Efficacy of Cyclophosphamide Combined with Prednisone in Membranous Nephropathy Patients with Different Cytochrome P450 2B6 Gene Polymorphisms and Analysis of Factors Influencing the Efficacy

Drug Design, Development and Therapy, 2022
Min Zhang,1 Yao Lv,2 Haokui Liu3 1Department of Nephrology, Bayannur Hospital, Bayannur, Inner Mongolia, People’s Republic of China; 2Department of Orthopedics, the Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong, People ...
Zhang M, Lv Y, Liu H
doaj  

Aquaporin 1 elicits cell motility and coordinates vascular bed formation by downregulating thrombospondin type‐1 domain‐containing 7A in glioblastoma

Cancer Medicine, 2020
Background Aquaporin (AQP) 1 expression has been linked with tumor malignancy but its role in glioblastoma (GBM), a lethal glioma, remains to be clarified. Methods AQP1 expression was examined in 33 human GBM specimens by immunohistochemistry. GBM cells (
Masahiro Oishi, Seiichi Munesue, Ai Harashima, Mitsutoshi Nakada, Yasuhiko Yamamoto, Yasuhiko Hayashi   +5 more
doaj   +1 more source

Human anti-thrombospondin type 1 domain-containing 7A antibodies induce membranous nephropathy through activation of lectin complement pathway

, 2018
To investigate whether the human anti-thrombospondin type 1 domain-containing 7A (THSD7A) antibody-induced membranous nephropathy (MN) is mediated by activating lectin complement pathway.
Zheng Wang, Yanna Dou, Lu Wen, Zhanzheng Zhao   +3 more
core   +1 more source

Characteristics of idiopathic membranous nephropathy (MN) patients with enhanced granular expression of thrombospondin type-1 domain-containing 7A (THSD7A) or M-type phospholipase A2 receptor (PLA2R) in the glomeruli.

, 2015
Characteristics of idiopathic membranous nephropathy (MN) patients with enhanced granular expression of thrombospondin type-1 domain-containing 7A (THSD7A) or M-type phospholipase A2 receptor (PLA2R) in the glomeruli.
Hideo Yasuda (710367), Satoshi Baba (540358), Naro Ohashi (168272), Akihiko Kato (798462), Takamasa Iwakura (798461)   +4 more
core   +1 more source

Additional file 3: Figure S2. of Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway

, 2016
The approach of construct thsd7a transgenic zebrafish. Representative image is the flow chart of making transgenic fish construct. PCR amplified cassette containing GFP was flanked by target homologous BAC sequence indicated by gray box.
Lawrence Liu (3458792), Min-Hsuan Lin (113008), Jie-Peng Jiang (3458795), Li-En Jao (3458801), Yung-Jen Chuang (186923), Yi-Ching Huang (3458798), Zih-Yin Lai (3458804)   +6 more
core   +1 more source