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Clonogenic Culture of Mouse Thymic Epithelial Cells
2019The thymus plays an essential role in the development and selection of T cells by providing a unique microenvironment that is mainly composed of thymic epithelial cells (TECs). We previously identified stem cells of medullary TECs (mTECs) that are crucial for central tolerance induction using a novel clonogenic culture system.
Miho, Sekai +2 more
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Effects of tacrolimus on rat thymic epithelial cells
Transplantation Proceedings, 2000FK506 is an immunosuppressive agent that was discovered in Japan. Many experiments on organ transplantation have shown the prolongation of allograft survival in animals by treatment with FK506. Previous studies have also shown that FK506 has a remarkable immunosuppressive effect and improves the outcome of liver transplantation.
K, Fujikawa +7 more
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Antibodies to thymic epithelial cells in myasthenia gravis
Journal of Neuroimmunology, 1991The presence of anti-thymus antibodies was investigated in the serum of 36 patients with myasthenia gravis (MG). Using an immunofluorescence technique on frozen thymic sections, we found 45% of patients sera reacting with normal or MG thymuses. Staining was confined to subcapsular and medullary keratin-positive epithelial cells.
D, Safar +3 more
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Replication of cytomegalovirus in human thymic epithelial cells
Medical Microbiology and Immunology, 1989Cytomegalovirus (CMV) has often been cited as a cause of immune suppression in children, yet little is known of the mechanisms through which this agent might affect immune function. We have succeeded in using CMV to productively infect cultured human fetal and infantile thymic epithelial (TE) cells. Morphological changes were apparent by 2-4 days after
K, Numazaki +5 more
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THYMIC EPITHELIAL CELL CONTAINS ACETYLCHOLINE RECEPTOR
The Lancet, 1977E K, Engel +3 more
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Microenvironmental reprogramming of thymic epithelial cells to skin multipotent stem cells
Nature, 2010Paola Bonfanti +2 more
exaly
Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development
Nature, 2018Corey N Miller +2 more
exaly

