Results 81 to 90 of about 4,567,849 (254)

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

The Murine Epithelial Thymic Microenvironment Is Governed by Eph/Ephrin Signalling

Cells
Although the relevance of thymic epithelial cell–thymocyte interactions for thymus function has long been emphasised, the mechanisms that govern the biology of thymic epithelial cells (TECs) are not fully understood.
Sara Montero-Herradón, David Alfaro, Agustín G. Zapata, Javier García-Ceca   +3 more
doaj   +1 more source

Live-cell imaging reveals the relative contributions of antigen-presenting cell subsets to thymic central tolerance

Nature Communications, 2019
Both thymic epithelial cells and dendritic cells present self antigens in the thymus to mediate thymic selection and T cell tolerance. Here the authors quantify, using two-photon live imaging of mouse thymic slices, the relative contribution of these two
J. N. Lancaster, H. M. Thyagarajan, J. Srinivasan, Y. Li, Z. Hu, L. I. R. Ehrlich   +5 more
doaj   +1 more source

Interleukin 7 from maternal milk crosses the intestinal barrier and modulates T-cell development in offspring [PDF]

, 2011
Background Breastfeeding protects against illnesses and death in hazardous environments, an effect partly mediated by improved immune function. One hypothesis suggests that factors within milk supplement the inadequate immune response of the offspring,
Andrew M Prentice, Prentice, Andrew M., Ngom, Pa T., Pa Tamba Ngom, Richard Aspinall, Ngom, Pa Tamba, Prentice, Andrew M, Aspinall, Richard, Andrew M. Prentice   +8 more
core   +2 more sources

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Understanding the Thymic Microenvironment: the Cellular and Molecular Basis of T Cell Development

Central Asian Journal of Medical Sciences, 2016
Objectives: The thymus is a primary lymphoid organ that provides specialized microenvironment for T cell development. A variety of thymic stromal cells form the thymic tissue architecture and critically regulate the development and repertoire selection ...
Takeshi Nitta
doaj   +1 more source

High‐Sugar Diet and Intestinal Diseases: A Shared Microbiota–Barrier–Immunity–Metabolism Axis in Inflammatory Bowel Disease, Food Allergy, and Colorectal Cancer

iNew Medicine, EarlyView.
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang, Yajuan Wu, Huayang Sheng, Shouhong Jiang, Jinping Cheng, Ye Kuang, Miao Liu, Lei Feng, Yanan Sun, Jinzhi Duan   +9 more
wiley   +1 more source

Thymic Neuroblastoma within a Thymic Cyst in an Adult

Case Reports in Oncology, 2012
Case Presentation: A 65-year-old female patient with no clinical manifestations was hospitalized for examination and treatment of an anterior mediastinal tumor found at the time of a regular health checkup.
Yuichiro Ueda, Mitsugu Omasa, Toshihiko Taki, Ryo Okabe, Hiroyuki Cho, Tsuyoshi Shoji, Cheng-long Huang, Yoshiaki Yuba   +7 more
doaj   +1 more source

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

Long-term persistence of functional thymic epithelial progenitor cells in vivo under conditions of low FOXN1 expression.

PLoS ONE, 2014
Normal thymus function reflects interactions between developing T-cells and several thymic stroma cell types. Within the stroma, key functions reside in the distinct cortical and medullary thymic epithelial cell (TEC) types. It has been demonstrated that,
Xin Jin, Craig S Nowell, Svetlana Ulyanchenko, Frances H Stenhouse, C Clare Blackburn   +4 more
doaj   +1 more source