Results 11 to 20 of about 16,647 (226)
Thymic stromal lymphopoietin blocks early stages of breast carcinogenesis [PDF]
Journal of Clinical Investigation, 2016 Advances in the field of cancer immunology, including studies on tumor-infiltrating CD8(+) cytotoxic T lymphocytes (CTLs), have led to new immunotherapeutics with proven efficacy against late-stage cancers.
Cipolat +14 more
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Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitis [PDF]
Nature Medicine, 2013 Eosinophilic esophagitis (EoE) is a food allergy-associated inflammatory disease characterized by esophageal eosinophilia. Current management strategies for EoE are nonspecific, and thus there is a need to identify specific immunological pathways that could be targeted to treat this disease. EoE is associated with polymorphisms in the gene that encodes
Noti, Mario +29 more
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Thymic stromal lymphopoietin controls hair growth [PDF]
Stem Cell Reports, 2022 Skin tissue regeneration after injury involves the production and integration of signals by stem cells residing in hair follicles (HFSCs). Much remains unknown about how specific wound-derived factors modulate stem cell contribution to hair growth. We demonstrate that thymic stromal lymphopoietin (TSLP) is produced in response to skin injury and during
Shannon, Jessica L. +5 more
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Медицинский вестник Юга России, 2022 Objective: to investigate correlation between thymic stromal lymphopoietin and bronchial asthma course and control in patients of different age groups.
A. V. Kamaev +5 more
doaj +1 more source
Jornal de Pediatria, 2020 Objective: To investigate the differential expression of the thymic stromal lymphopoietin isoforms, short and long, and discern their biological implications under eosinophilic gastroenteritis.
Hongmei Guo +3 more
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Thymic stromal lymphopoietin [PDF]
Annals of the New York Academy of Sciences, 2010 Thymic stromal lymphopoietin (TSLP) is an epithelial cell‐derived cytokine expressed in skin, gut, lungs, and thymus. TSLP signals via a TSLP receptor (TSLPR), a heterodimer of the IL‐7 receptor α chain and the TSLPR chain. The TSLPR chain is closely related to the common receptor γ chain that is expressed on a wide range of cell types in the adaptive ...
Rui, He, Raif S, Geha
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Role of thymic stromal lymphopoietin in allergy and beyond. [PDF]
Nat Rev Immunol, 2023 Ebina-Shibuya R, Leonard WJ.
europepmc +2 more sources
Thymic Stromal Lymphopoietin and Cancer [PDF]
The Journal of Immunology, 2014 Abstract Originally shown to promote the growth and activation of B cells, thymic stromal lymphopoietin (TSLP) is now known to have wide-ranging effects on both hematopoietic and nonhematopoietic cell lineages. These include dendritic cells, basophils, mast cells, B cells, epithelial cells, and CD4+, CD8+, and NK T cells. Although TSLP’s
Emma, Lo Kuan, Steven F, Ziegler
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TSLP and asthma: fellow travelers [PDF]
Exploration of Asthma & Allergy, 2023 The incidence of asthma, a heterogeneous inflammatory disease affecting over 300 million people worldwide, continues to increase in developed countries.
David El-Qutob, Antonio Letran
doaj +1 more source
Use of the complex of models of regression for analysis of the factors that determine the severity of bronchial asthma [PDF]
, 2020 Background: According to an International Study of Asthma and Allergies in Childhood (ISAAC), the prevalence of asthma in children of 6-7 years old has increased by 10%, and at the age of 13-14 years by 16% over the last decade.
Kozhyna, Olga S., Pihnastyi, O. M.
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