Results 71 to 80 of about 184,554 (216)

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Thymic stromal lymphopoietin induction is mediated by the major whey proteins α-lactalbumin and β-lactoglobulin through the NF-κB pathway in immune cells

, 2015
α-Lactalbumin and β-lactoglobulin are two major whey proteins that specifically bind immunoglobulin E and are suspected as major allergens causing cow's milk allergy (CMA).
B Y Park, Y W Park, Jae Min Yoo, M S Nam, S G Jeong, J Y Son, S Y Yoon, Jae Wha Kim   +7 more
core   +1 more source

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

Allergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith, Nicholas P. West, Stanley Du Preez, Hugh A. Sampson, Peter W. Hellings, David Price, Liam O'Mahony, Carina Venter, Cezmi A. Akdis, Gil Yosipovitch   +9 more
wiley   +1 more source

European Guidelines on Eosinophilic Esophagitis: Evidence‐Based Statements and Recommendations for Diagnosis and Management in Children and Adults. Part 1: Diagnosis, Epidemiology and Natural History

Allergy, EarlyView.
The European evidence‐based guidelines on eosinophilic esophagitis (Part 1). This infographic summarizes the methodological framework and core clinical outputs of the updated consensus developed by multidisciplinary experts from EUREOS, EAACI, ESPGHAN, and ESP.
Alfredo J. Lucendo, Javier Molina‐Infante, Ángel Arias, Ulrike von Arnim, Henrik Bergquist, Luc Biedermann, Albert J. Bredenoord, Marie Carlson, Javier Chahuan, Jorge Amil Dias, Thomas Eiwegger, Sara Feo‐Ortega, Sandra L. Garcia‐Dionisio, Matteo Ghisa, Jesús González‐Cervera, Thomas Greuter, Danila Guagnozzi, Carolina Gutiérrez‐Junquera, Lucía Gutiérrez‐Ramírez, Cord Langner, Helen Larsson, Anne Lund Krarup, Salvatore Oliva, Alexandra Papadopoulou, Francesca Racca, Cecilio Santander, Edoardo Vincenzo Savarino, Christoph Schlag, Alain M. Schoepfer, Martin A. Storr, Antonio Tejera‐Muñoz, Noam Zevit, Stephen E. Attwood, Alex Straumann   +33 more
wiley   +1 more source

Inflammatory Mediators Associated With Corticosteroid Responsiveness During Asthma Attacks

Clinical &Experimental Allergy, EarlyView.
ABSTRACT Higher baseline sputum/serum eotaxin‐3 and serum IL‐5 levels were associated with greater FEV1 improvement following OCS during asthma attacks. Corticosteroid‐induced inflammatory modulation differed across T2 phenotypes during asthma attacks.
Carlos Celis‐Preciado, Elsa Ben Hamou Kuijpers, Mohamed‐Ilias Kourid, Simon Leclerc, Martine Duval, Dominic O. Cliche, Félix‐Antoine Vézina, Pierre Larivée, Samuel Lemaire‐Paquette, Philippe Lachapelle, Martin Klein, Simon Couillard   +11 more
wiley   +1 more source

A profibrotic role for thymic stromal lymphopoietin in systemic sclerosis

Annals of the Rheumatic Diseases, 2013
Objective: [corrected] Systemic sclerosis (SSc) is an autoimmune disease characterised by progressive fibrosis. Although SSc shares pathogenetic features with other autoimmune diseases, the participation of profibrotic Th2 cytokines is unique to SSc, but the mechanisms of Th2 skewing are unknown.
Alicia, Usategui, Gabriel, Criado, Elena, Izquierdo, Manuel J, Del Rey, Patricia E, Carreira, Pablo, Ortiz, Warren J, Leonard, José L, Pablos   +7 more
openaire   +4 more sources

Thymic stromal lymphopoietin does not activate human basophils [PDF]

Journal of Allergy and Clinical Immunology, 2018
International ...
Salabert-Le Guen, Nina, Hemont, Caroline, Delbove, Agathe, Poli, Caroline, Braudeau, Cécile, Fantou, Aurelie, Amouriaux, Karine, Bériou, Gaëlle, Martin, Jerome C, Colas, Luc, Soumelis, Vassili, Josien, Regis   +11 more
openaire   +4 more sources

Inhaled dsRNA and rhinovirus evoke neutrophilic exacerbation and lung expression of thymic stromal lymphopoietin in allergic mice with established experimental asthma.

, 2014
Rhinovirus infection or dsRNA stimulation increased thymic stromal lymphopoietin (TSLP), an upstream pro-allergic cytokine, in asthmatic bronchial epithelial cells.
Uller, Lena, Brandelius, Angelica, Brandelius, Angelica,, Akbarshahi, Hamid,, Johnston, S L, Mahmutovic Persson, Irma,, Akbarshahi, Hamid, Glanville, N, Mahmutovic Persson, Irma, Bartlett, N W, Lund University., Uller, Lena,   +11 more
core   +1 more source

Environmental effect on health: Air pollution and smoke

Environmental Disease, 2016
This review has discussed various topics related to environmental health. The major findings highlighted are air pollution, children and adult vulnerability, cytokines related to interleukin-33, thymic stromal lymphopoietin, tobacco smoke related to ...
Marianne Frieri, Krishan Kumar, Anthony Boutin   +2 more
doaj   +1 more source

Toll-like receptor-ligand induced thymic stromal lymphopoietin expression in primary equine keratinocytes. [PDF]

, 2020
BACKGROUND Thymic stromal lymphopoietin (TSLP) plays a key role in the development of allergic inflammation. Little is known about possible triggers of equine TSLP expression. HYPOTHESIS/OBJECTIVES To investigate TSLP expression in equine insect
Chu, Shui Ling, Müller, Eliane Jasmine, Arnaud Galichet, Shui Chu Ling, Cvitas, Iva, Iva Cvitas, Eliane J. Müller, Galichet, Arnaud, Marti, Eliane Isabelle, Eliane Marti, Müller EJ, Cvitas I, Ling SC, Marti E, Galichet A   +14 more
core   +2 more sources