Results 81 to 90 of about 10,319 (186)
Integrated Immune, Epithelial and Lipid Pathways in NSAID‐Exacerbated Respiratory Disease
Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.ABSTRACT NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic inflammatory disorder characterized by asthma, chronic rhinosinusitis with nasal polyps and respiratory reactions to cyclooxygenase‐1 inhibiting nonsteroidal anti‐inflammatory drugs (NSAID).
Piotr Szatkowski, Lucyna Mastalerz
wiley +1 more source
Chinese Medical Journal, 2018 Objective: Allergic airway diseases (AADs) are a group of heterogeneous disease mediated by T-helper type 2 (Th2) immune response and characterized with airway inflammation and remodeling, including allergic asthma, allergic rhinitis, and chronic ...
Xiu-Juan Yao +2 more
doaj +1 more source
Gamma Delta T Cells in Shrimp Allergy Express a Unique Cytotoxic Cytokine Profile
Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.ABSTRACT Shellfish allergy is the most common food allergy in adults and the third most common in children. γδ T cells have been identified as playing a critical role in antigen tolerance in allergic diseases in mouse models. In humans, γδ T cells may play a regulatory role in peanut immunotherapy, and their role in shrimp allergy remains unclear.
Brenda Bin Su +9 more
wiley +1 more source
TSLP‐targeting therapy: Beyond allergy?
Clinical and Translational Medicine, 2023 Risa Ebina‐Shibuya, Warren J. Leonard
doaj +1 more source
The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta +2 more
wiley +1 more source
OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 8, Page 1318-1331, August 2026.OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta +4 more
wiley +1 more source
Thymic Stromal Lymphopoietin (TSLP)
Current allergy and asthma reportsPurpose of the Review: Thymic stromal lymphopoietin (TSLP) is increasingly recognized for its pivotal role in the pathogenesis of various epithelial-driven chronic inflammatory diseases. This review navigates the existing evidence on TSLP, with a particular focus on asthma, before delving into the current understanding of its role in chronic ...
de Corso, Eugenio +8 more
openaire +1 more source
Potential of alarmin-targeted bispecific and combination therapies in airway disease
Frontiers in AllergyThymic stromal lymphopoietin (TSLP), IL-33, and IL-25 are epithelial-derived proinflammatory alarmin cytokines that drive inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease (COPD).
H. Kiyomi Komori, Hector Ortega
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Clinical, Cosmetic and Investigational Dermatology, 2022 Yu-qing Hu, Jian-zhong Zhang Department of Dermatology, Peking University People’s Hospital, Beijing, People’s Republic ChinaCorrespondence: Jian-zhong Zhang, Tel +86-10-88325472, Fax +86-10-68318386, Email rmzjz@126.comBackground: Bullous pemphigoid (BP)
Hu YQ, Zhang JZ
doaj
The last step to achieve barrier damage control
Frontiers in ImmunologyHeterogeneity characterises inflammatory diseases and different phenotypes and endotypes have been identified. Both innate and adaptive immunity contribute to the immunopathological mechanism of these diseases and barrier damage plays a prominent role ...
Ilaria Baglivo +5 more
doaj +1 more source