Results 81 to 90 of about 184,554 (216)

Trans‐resveratrol alleviates inflammation and improves skin barrier function via aryl hydrocarbon receptor pathway in human reconstructed epidermis

International Journal of Cosmetic Science, EarlyView.
In a cytokine‐challenged human epidermal model, trans‐resveratrol reduces inflammation (IL‐1α) and oxidative stress markers (CYP1A1, CYP1B1), while modulating the expression of barrier‐related genes (LOR, OCLN) and differentiation‐associated CASP14. This supports its role as a multifunctional active for sensitive and compromised skin.
Irini M. Dijkhoff, Sandeep Keshavan, Regina G. Daré, Alke Petri‐Fink, Marc Eeman, Agnès Tessier, Barbara Rothen‐Rutishauser   +6 more
wiley   +1 more source

Andrographolide suppresses thymic stromal lymphopoietin in phorbol myristate acetate/calcium ionophore A23187-activated mast cells and 2,4-dinitrofluorobenzene-induced atopic dermatitis-like mice model

, 2016
Chun-xiao Li,* Hua-guo Li,* Hui Zhang,* Ru-hong Cheng, Ming Li, Jian-ying Liang, Yan Gu, Bo Ling, Zhi-rong Yao, Hong Yu Department of Dermatology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of ...
Cheng RH, Ling B, Gu Y, Li CX, Zhang H, Yao ZR, Liang JY, Li HG, Li M, Yu H   +9 more
core  

Immune stimulus exposure as a trigger for the development of chronic pruritus and circulating blood type 2 inflammationCapsule Summary

JAAD International
Background: Chronic pruritus (CP) is a poorly characterized condition associated with intense pruritus without a primary skin eruption. This condition tends to emerge more commonly in older adults, and there is limited research on triggering factors ...
Jaya Manjunath, BS, Viviane Liao, BS, Anusha Kambala, BS, Aaron Bao, BA, Alexander L. Kollhoff, MD, Emily Z. Ma, BS, Brenda Umenita Imo, MS, Hannah Cornman, BS, Sriya V. Reddy, BS, Kevin K. Lee, BS, Weiying Lu, BS, Selina M. Yossef, BA, Madan M. Kwatra, PhD, Shawn G. Kwatra, MD   +13 more
doaj   +1 more source

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review

Immunology, EarlyView.
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann, Henrique R. Dal‐Pizzol, Louise M. Lückmann, Davi E. Salini, Bruna C. Hasckel, Mikaeli Minati, Bruno Kluwe‐Schiavon, Tatiana Barichello   +7 more
wiley   +1 more source

Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach, Ausra Ramanauskaite, Sašo Ivanovski, Pingping Han, Frank Schwarz, Emilio A. Cafferata   +5 more
wiley   +1 more source

Evaluation of Two Induction Protocols for Oclacitinib in Dogs

Veterinary Dermatology, EarlyView.
Background: Oclacitinib is approved for the treatment of canine atopic dermatitis and pruritus. The conventional administration protocol includes twice‐daily oral dosing for 14 days with a subsequent reduction to once‐daily administration. This reduction sometimes leads to an increase in pruritus.
Paulina J. C. Popp, Ralf S. Mueller, Laura Widorn, Laura Udraite‐Vovk, Ulrike Mueller, Tamara Weitzer   +5 more
wiley   +1 more source

Thymic stromal lymphopoietin levels after allogeneic hematopoietic stem cell transplantation

, 2022
Background: Thymic stromal lymphopoietin (TSLP) is an immunoregulatory, Th2-polarizing cytokine produced by epithelial cells. We hypothesized that TSLP affects immune reconstitution after hematopoietic stem cell transplantation (HSCT) leading to ...
Lars Peter Ryder, Dina Leth Møller, Ryder, Lars Peter, Pedersen, Anders Elm, Müller, Klaus, Claus Henrik Nielsen, Katrine Kielsen, Kielsen, Katrine, Anders Elm Pedersen, Klaus Müller, Sengeløv, Henrik, Henrik Sengeløv, Møller, Dina Leth, Nielsen, Claus Henrik   +13 more
core   +1 more source

Cancer‐associated fibroblast heterogeneity across solid and haematological malignancies: Lessons from colorectal cancer and multiple myeloma

The Journal of Physiology, EarlyView.
Abstract figure legend CAF origins and plasticity give rise to distinct phenotypes with immunosuppressive functions in colorectal cancer and multiple myeloma. These distinct CAF phenotypes contribute to immunosuppressive tumour microenvironments through ECM remodelling, cytokine signalling and immune regulation.
Hui Mo, Haoyan Han, Michael O'Dwyer, Eileen Reidy, Aideen E. Ryan   +4 more
wiley   +1 more source

Multifactorial Causes and Consequences of TLSP Production, Function, and Release in the Asthmatic Airway

Biomolecules
Disruption of the airway epithelium triggers a defensive immune response that begins with the production and release of alarmin cytokines. These epithelial-derived alarmin cytokines, including thymic stromal lymphopoietin (TSLP), are produced in response
Danica L. Brister, Hafsa Omer, Christiane E. Whetstone, Maral Ranjbar, Gail M. Gauvreau   +4 more
doaj   +1 more source

Skin tissue expression and serum level of thymic stromal lymphopoietin in patients with psoriasis vulgaris

Dermatology Reports, 2019
Thymic stromal lymphopoietin (TSLP) is known to be associated with allergic diseases. It is also suggested that TSLP has a role in autoimmune diseases such as psoriasis; however, the associated pathways remain unknown.
Oki Suwarsa, Hartati Purbo Dharmadji, Endang Sutedja, Lengga Herlina, Putri Reno Sori, Reti Hindritiani, Reiva Farah Dwiyana, Hendra Gunawan   +7 more
doaj   +1 more source