Mesenchymal stromal cell‐and fibroblast‐expressing Linx paralogue (Meflin) is expressed in embryonic meninges and contributes to meningeal homeostasis. In meningiomas, elevated Meflin correlates with higher grade and recurrence. Single‐cell RNA sequencing revealed a Meflin‐high tumor cell subset marked by reduced proliferation, WNT6 expression, and ...
Yukihiro Shiraki +13 more
wiley +1 more source
Thymidine-Inosine Dimer Building Block for Reversible Modification of Synthetic Oligonucleotides. [PDF]
Kolganova NA +6 more
europepmc +1 more source
Targeting Genome Maintenance Defects of Cancers Using Chain‐Terminating Nucleoside Analogs
Nucleoside analogs interfere with DNA replication either by their chain‐terminating properties or by serving as DNA damage on the template. The genome maintenance pathways required to maintain cellular tolerance to each nucleoside analog vary depending on the drug.
Ryotaro Kawasumi +2 more
wiley +1 more source
CRISPR-Cas targeting in <i>Haloferax volcanii</i> promotes within-species gene exchange by triggering homologous recombination. [PDF]
Choudhary DK +3 more
europepmc +1 more source
Maternal TCF12 ensures the competence of fertilisation by controlling the expression of Astl and the proper location of cortical granules. Furthermore, maternal TCF12 maintains the phosphatase activity of PP2A by regulating the expression of Arpp19. Oocyte‐specific deletion of Tcf12 leads to fertilisation defects as well as ZGA failure at the 2‐cell ...
Lan‐Rui Cao +7 more
wiley +1 more source
KRP3 Stability Controls Rice Plant Architecture and Productivity via MPK3‐Mediated Phosphorylation
ABSTRACT Yield is a critical agronomic trait in cereal crops, shaped by factors like tiller and seed number, and seed weight. Understanding the factors governing these traits will help in improving the yield of plants. In this study, we identified an orphan gene, KRP3, belonging to cereal crops as a key regulator of rice plant architecture.
Gopal Banerjee +6 more
wiley +1 more source
Dependence of <i>Mycoplasma bovis</i> on a novel nucleoside transporter for survival in association with host cells. [PDF]
Geng S +10 more
europepmc +1 more source
Host-specificity assessment of feline alphaherpesvirus-1 derived immunocontraceptive candidates in non-feline models. [PDF]
Cottingham E +4 more
europepmc +1 more source
Optimization of <i>q</i> Value for Sensitive Detection of Uridine and Thymidine Nucleosides by MS<sup>3</sup>. [PDF]
Duan Z, Wang C, Wang Y.
europepmc +1 more source
Superiority of Chrysophyllum oliviforme in the green synthesis of highly stable ZnO nanoparticles: metabolomic profiling, quadruple antiviral screening, and comparative MD simulations. [PDF]
Melk MM, El-Sayed AF.
europepmc +1 more source

