Results 181 to 190 of about 62,555 (239)

Induction of an antiviral response by interferon requires thymidine kinase.

, 1983
John A. Lewis, Elena Mengheri, Mariano Estéban   +2 more
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Baculovirus Replication: Stimulation of Thymidine Kinase and DNA Polymerase Activities in Spodoptera frugiperda Cells Infected with Trichoplusia ni Nuclear Polyhedrosis Virus

, 1981
D. C. Kelly
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Effect of in vitro Mutations in a Vaccinia Virus Early Promoter Region Monitored by Herpes Simplex Virus Thymidine Kinase Expression in Recombinant Vaccinia Virus

, 1987
Barbara E.H. Coupar, D. B. Boyle, G W Both   +2 more
openalex   +1 more source

Association of thymidine kinase-1 with prostate cancer

Asian Journal of Surgery
Changyi Jiang, Wenting Zhou, Linhui Wang, Changxing Ke   +3 more
doaj  

Correlation of the Virus Sequence Content and Biological Properties of Cells Carrying the Herpes Simplex Virus Type 2 Thymidine Kinase Gene

, 1982
A. C. Minson, Susanne Bell, Kenneth F. Bastow   +2 more
openalex   +1 more source

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The thymidine phosphorylating kinases

Biochimica et Biophysica Acta, 1961
Abstract The pattern of the phosphorylation reactions when supernatant fractions from leukaemic spleen and lymph nodes of mice are incubated with an ATP regenerating system and [2- 14 C]thymidine has been studied. The results indicate that TDP is not an intermediate in the formation of TTP, the latter compound being formed by pyrophosphate addition ...
P.A. Bianchi, J. A. V. Butler, A.R. Crathorn, K.V. Shooter   +3 more
openaire   +4 more sources

Mitochondrial Thymidine Kinase Inhibitors [PDF]

Current Topics in Medicinal Chemistry, 2005
Mitochondrial thymidine kinase or TK-2 belongs to the family of mammalian deoxynucleoside kinases (dNKs) that catalyze the phosphorylation of deoxynucleosides to their corresponding deoxynucleoside monophosphates by gamma-phosphoryl transfer of ATP.
Federico Gago, Eva-María Priego, Ana-Isabel Hernández, Fátima Rodríguez-Barrios, María-Jesús Pérez-Pérez, María-José Camarasa, Jan Balzarini   +6 more
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Thymidine Kinases in Archaea

Nucleosides, Nucleotides and Nucleic Acids, 2006
Twenty-six fully sequenced archaeal genomes were searched for genes coding for putative deoxyribonucleoside kinases (dNKs). We identified only 5 human-like thymidine kinase 1 genes (TK1s) and none for non-TK1 kinases. Four TK1s were identified in the Euryarchaea and one was found in the Crenarchaea, while none was found in Nanoarchaeum.
Michael P. B. Sandrini, Anders R. Clausen, Jure Piškur, A Matakos   +3 more
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Mitochondrial-specific thymidine kinase

Archives of Biochemistry and Biophysics, 1973
Abstract Thymidine kinase activity has been demonstrated in purified mitochondria prepared from animal tissue, wild-type tissue culture cells, and BrdU-resistant cell lines. The BrdU-resistant cell lines lack a soluble cytoplasmic thymidine kinase present in wild-type cells, but continue to exhibit the minor mitochondrial activity.
Barbara J. Meyer, Arnold J. Berk, David A. Clayton   +2 more
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Thymidine Kinase in Megaloblastic Anaemia

British Journal of Haematology, 1976
Summary. Thymidine kinase has been measured in phytohaemagglutinin (PHA)‐stimulated lymphocytes from 13 normal subjects and eight patients with megaloblastic anaemia. The levels in normal subjects ranged from 0.20 to 2.10 units/mg protein (mean 0.903 units/mg protein) and in megaloblastic anaemia from 2.99 to 9.97 units/mg protein (mean 5.76 units/mg ...
A. V. Hoffbrand, J. W. L. Hooton
openaire   +3 more sources