TYMP (thymidine phosphorylase) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on TYMP (thymidine phosphorylase), with data on DNA, on the protein encoded, and where the gene is implicated.
Bijnsdorp, IV, Peters, GJ
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Poor Outcome in a Mitochondrial Neurogastrointestinal Encephalomyopathy Patient with a Novel TYMP Mutation: The Need for Early Diagnosis [PDF]
Case Reports in Neurology, 2012 Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a devastating autosomal recessive disorder due to mutations in TYMP, which cause loss of function of thymidine phosphorylase (TP), nucleoside accumulation in plasma and tissues and ...
Mauro Scarpelli +9 more
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Validation of an Immunoassay for Anti-thymidine Phosphorylase Antibodies in Patients with MNGIE Treated with Enzyme Replacement Therapy [PDF]
Molecular Therapy: Methods & Clinical Development, 2018 Erythrocyte encapsulated thymidine phosphorylase is recombinant Escherichia coli thymidine phosphorylase encapsulated within human autologous erythrocytes and is under development as an enzyme replacement therapy for the ultra-rare inherited metabolic ...
Michelle Levene +5 more
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Expression of Thymidine Phosphorylase in Lymph Nodes Involved with Mycosis Fungoides and Sézary Syndrome [PDF]
Advances in Hematology, 2011 Thymidine phosphorylase may be overexpressed in both neoplastic cells and tumor stromal cells in a variety of malignancies. Our study explores thymidine phosphorylase expression in lymph nodes (LNs) from patients with mycosis fungoides (MF) or Sézary ...
Xingcao Nie +4 more
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Comparison of thymidine phosphorylase expression and prognostic factors in gallbladder and bile duct cancer [PDF]
BMC Cancer, 2010 Background Biliary tract cancers have limitations in information about different location-related pathogenesis and clinico-pathological characteristics.
You Young +6 more
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Mycoplasma PneumoniaeThymidine Phosphorylase [PDF]
Nucleosides, Nucleotides and Nucleic Acids, 2014 Mycoplasma pneumoniae (Mpn) is a human pathogen causing acute respiratory diseases and accounts for approximately 30% cases of community-acquired pneumonia. Co-infection with Mycoplasmas compromises the efficacy of anticancer and antiviral nucleoside analog-based drugs due to the presence of Mycoplasma thymidine phosphorylase (TP).
Wang, L. +2 more
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Safety and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase in Mitochondrial Neurogastrointestinal Encephalomyopathy [PDF]
Journal of Clinical Medicine, 2019 Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an ultra-rare autosomal recessive disorder of nucleoside metabolism that is caused by mutations in the nuclear thymidine phosphorylase gene (TYMP) gene, encoding for the enzyme thymidine ...
Bridget Bax +2 more
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Expression and Retention of Thymidine Phosphorylase in Cultured Reticulocytes as a Novel Treatment for MNGIE [PDF]
Molecular Therapy: Methods & Clinical Development, 2020 Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is a rare autosomal metabolic disorder caused by thymidine phosphorylase (TP) deficiency. Successful therapeutic interventions for this disease rely on a means for efficient and long-lasting ...
Marjolein Meinders +5 more
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The cytosol activity of thymidine phosphorylase in endometrial cancer [PDF]
Journal of Experimental & Clinical Cancer Research, 2008 Background Thymidine phosphorylase (TP) is identical with platelet-derived endothelial cell growth factor (PD-ECGF) which promotes angiogenesis. The aim of this study was to evaluate the cytosol activity of TP in tumor samples from patients with ...
Bieńkiewicz Andrzej +3 more
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Thymidine Phosphorylase Gene Expression in Stage III Colorectal Cancer [PDF]
Clinical Medicine Insights: Oncology, 2012 Background The thymidine phosphorylase (TP) enzyme has several tumor-promoting functions. The aim of this study was to explore TP gene expression in relation to clinical and histopathological data obtained from patients with stage III colorectal cancer ...
Elinor B. Lindskog +4 more
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