Results 101 to 110 of about 74,896 (329)

Enhancing the Sensitivity of Colorimetric Aptasensor Through Cd2+‐Thymine Interactions in ssDNA Loops for Food Contaminant Detection

open access: yesFood Safety and Health, EarlyView.
This picture illustrates a novel aptamer‐based colorimetric assay, which demonstrates that high sensitivity, selectivity, and reliability for the rapid detection of cadmium ions (Cd2+) in water. Molecular dynamics (MD) simulations have revealed that the complexes are more stable, with Cd2+ binding more tightly to the thymine (T) within the aptamer loop.
Xuyan Li   +7 more
wiley   +1 more source

γ-PNA PREORGANIZATION: SYNTHESIS OF MODEL DIMER AND ITS STRUCTURE STUDY BY 2D NMR SPECTROSCOPY

open access: yesТонкие химические технологии, 2017
The synthesis of a dimer consisting of γ-thymine chiral monomer based on L-Ala and thymine aeg-PNA monomer (synthesized from deuterated glycine), in which the methylene protons of the pseudopeptide residue were exchanged with deuterium atoms, was ...
A. V. Dezhenkov   +4 more
doaj   +1 more source

A poly(thymine)–melamine duplex for the assembly of DNA nanomaterials

open access: yesNature Materials, 2020
Qian Li   +10 more
semanticscholar   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

The Graphene Oxide Memristive DNA Sensor for Taxonomic Fingerprint

open access: yesMacromolecular Materials and Engineering, EarlyView.
A graphene oxide–based memristive DNA sensor enables rapid, label‐free quantification of nucleotide base composition across 37%–55% GC with strong linear calibration. Delivering results within 2–5 min, the platform combines high sensitivity with minimal sample preparation, offering a practical tool for point‐of‐care diagnostics, genetic fingerprinting,
Konstantin G. Nikolaev   +4 more
wiley   +1 more source

Light‐Guided Molecular Patterning for High‐Throughput Single‐Molecule Mechanical Characterization

open access: yesSmall, EarlyView.
A light‐guided molecular patterning method is presented for high‐throughput single‐molecule characterization. The approach enables scalable and accessible molecular patterning without specialized lithography equipment. Patterned surfaces are compatible with downstream biophysical assays, demonstrated by magnetic tweezers and flow‐based single‐molecule ...
Hansol Choi, Andrew Ward, Wesley P. Wong
wiley   +1 more source

Twists and Turns of Liquid Crystals Unravelled by Small‐Angle Scattering

open access: yesSmall Methods, EarlyView.
X‐ray scattering provides valuable insights into material structure and self‐assembly. This review discusses the use of small‐ and wide‐angle X‐ray scattering (SWAXS) as well as grazing incident SWAXS for examining self‐assembled systems, especially liquid crystals.
Jessie Wong   +2 more
wiley   +1 more source

Advancing Single‐Walled Carbon Nanotubes toward Next‐Generation Electronic Materials: The Critical Roles of Purity and Processability

open access: yesSmall Methods, EarlyView.
Single‐walled carbon nanotubes (SWNTs) are promising for a wide range of applications. In particular, their exceptional electrical conductivity positions them as potential alternatives to traditional metal conductors. This review identifies the key mechanisms governing their conductivity within composites and proposes practical pathways for translating
Xiao Yu, Alex Adronov
wiley   +1 more source

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